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Brought to you by The NOMIS & Science Young Explorer Award VOLUME 383 | ISSUE 6684 | 16 FEB 2024 Editorial Editorial Science communication at scale By H. Holden Thorp Read more News In Brief News at a glance Read more In Depth  |  Science and the Media Jury rules noted climate scientist was defamed By Paul Voosen Verdict punishes bloggers who compared Michael Mann’s work to molestation Read more In Depth  |  Astronomy X-ray survey bolsters theory of universe’s expansion By Daniel Clery eROSITA telescope shows galaxies’ “clumpiness” matches predicted effect of dark energy, dark matter Read more In Depth  |  Science Policy What’s at stake for science in ‘abortion pill’ case By Meredith Wadman Supreme Court decision this summer could gut FDA’s authority over drugs Read more In Depth  |  Atmospheric Science Giant solar farms could provoke rainclouds in the desert By Paul Voosen Updrafts from dark solar panels could fuel storms Read more In Depth  |  Ecology Diet explains Serengeti grazers’ predictable migration By Elizabeth Pennisi Each species’ dining habits set the table for the next wave Read more Feature A river in flux By Daniel Grossman Extreme flooding and droughts may be the new norm for the Amazon, challenging its people and ecosystems Read more Insights Expert Voices Design national framework climate laws to enable low-carbon resilient transformation By Navroz K. Dubash Read more Perspective  |  Molecular Biology Telomerase misbehaves after a breakup By Nausica Arnoult, Thomas R. Cech Suppressing telomerase action at broken DNA preserves genome integrity Read more Perspective  |  Medicine HIV cure: The daunting scale of the problem By Janet D. Siliciano, Robert F. Siliciano Cure strategies are confounded by basic reservoir biology Read more Perspective  |  Immunology Decoding the autoantibody reactome By Jillian R. Jaycox, Yile Dai, et al. Autoantibodies influence a wide range of conditions beyond autoimmune diseases Read more Perspective  |  Plant Science Mixed-organism enzyme in plant defense By Elisha Thynne, Bostjan Kobe Plants commandeer a pathogen’s virulence factor to bolster immunity Read more Policy Forum  |  Ecology Conflation of reforestation with restoration is widespread By Catherine L. Parr, Mariska te Beest, et al. Across Africa, vast areas of nonforest are threatened by inappropriate restoration in the form of tree planting Read more Books et al.  |  History of Science The end of the auk By Mark V. Barrow An anthropologist recounts how a pair of 19th-century naturalists traced an elusive bird’s extinction in real time Read more Books et al.  |  Science and Society Managing expectations By Michael Travisano A political scientist urges readers to embrace the chaos and complexity of life Read more Letter Fund two extremely large US telescopes By Patrick McCarthy, Robert P. Kirshner, et al. Read more Letter Florida law undercuts US leadership in science By Thomas P. Kimbis Read more Letter Ethical treatment of Iran’s research animals By Atarodsadat Mostafavinia, Seyed K. Ghoreishi Read more Research Research Highlights In Science Journals By Sacha Vignieri, Marc S. Lavine, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Keith T. Smith, Mattia Maroso, et al. Editors’ selections from the current scientific literature Read more Research Article  |  IMMUNOLOGY The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity By Pankaj Sharma, Xiaolong Zhang, et al. Immunological B cells found within a specialized tissue structure express a lipid that augments antibody-mediated immunity. Read more Research Article  |  METABOLISM Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG By Jie Chen, Yabo Zhou, et al. The glycogenesis metabolite UDPG antagonizes lipogenesis and promotes storage of glucose carbon as glycogen in hepatocytes. Read more Research Article  |  PLANT SCIENCE Paired plant immune CHS3-CSA1 receptor alleles form distinct hetero-oligomeric complexes By Yu Yang, Oliver J. Furzer, et al. Pairs of intracellular immune receptors heterodimerize and oligomerize to activate immunity in plants. Read more Research Article  |  ANTIBIOTICS An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance By Kelvin J. Y. Wu, Ben I. C. Tresco, et al. A synthetic molecule preorganized for bacterial ribosome binding is highly effective against multi-drug-resistant bacteria Read more Research Article  |  OCEAN OXYGEN Oxygen rise in the tropical upper ocean during the Paleocene-Eocene Thermal Maximum By Simone Moretti, Alexandra Auderset, et al. Oxygenation of the low-latitude tropical North Pacific Ocean increased during the Paleocene-Eocene Thermal Maximum despite high global temperatures. Read more Research Article  |  PLANT IMMUNITY A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity By Yu Xiao, Guangzheng Sun, et al. A plant immunity protein interacts with a fungal cell wall–degrading enzyme to create immunogenic compounds. Read more Research Article  |  BATTERIES Superionic lithium transport via multiple coordination environments defined by two-anion packing By Guopeng Han, Andrij Vasylenko, et al. Ordering of sulfide and iodide builds a fast transport path of diverse lithium coordination geometries and anion neighbors. Read more Research Article  |  PHYSICAL CHEMISTRY Roaming in highly excited states: The central atom elimination of triatomic molecule decomposition By Zhenxing Li, Yan-lin Fu, et al. Roaming for photodissociation of sulfur dioxide in highly excited states was observed experimentally and confirmed theoretically. Read more Research Article  |  PHOTOCHEMISTRY Accelerated photochemical reactions at oil-water interface exploiting melting point depression By Ya-Ming Tian, Wagner Silva, et al. Melting point depression liquefies solid reactants to facilitate their photochemical coupling on the surface of water. Read more Research Article  |  CATALYSIS Electrically driven proton transfer promotes Brønsted acid catalysis by orders of magnitude By Karl S. Westendorff, Max J. Hülsey, et al. Electrochemical potential can shift protonation equilibria to accelerate acid-catalyzed reactions by up to 100,000-fold. Read more Research Article  |  MOLECULAR BIOLOGY ATR blocks telomerase from converting DNA breaks into telomeres By Charles G. Kinzig, George Zakusilo, et al. Human telomerase threatens genome integrity by adding telomeres to broken chromosomes and is held in check by ATR kinase signaling. Read more Research Article  |  LAYERED MATERIALS Water-induced strong isotropic MXene-bridged graphene sheets for electrochemical energy storage By Jiao Yang, Mingzhu Li, et al. Nanoconfined water induces alignment of strong, isotropic macroscopic graphene sheets for electrochemical energy storage. Read more Research Article  |  ECOLOGY Eco-evolutionary emergence of macroecological scaling in plankton communities By Jonas Wickman, Elena Litchman, et al. Eco-evolutionary dynamics informed by allometric scaling can predict large-scale patterns across planktonic food webs. Read more Research Article  |  ECOLOGY Interplay of competition and facilitation in grazing succession by migrant Serengeti herbivores By T. Michael Anderson, Staci A. Hepler, et al. A camera-trap survey, GPS-collared herbivores, and fecal DNA analysis elucidate the timing, arrival order, and interactions of migratory grazers. Read more Careers Working Life Exams with empathy By Jan Philipp Röer Read more Essay Essay  |  Immunology Protons are the new first responders By Bingxu Liu Human STING’s newfound function as a channel expands our understanding of immunity Read more Essay  |  Immunology Stem cells in disguise By Gabriele Casirati Epitope editing can empower targeted cancer immunotherapies Read more Essay  |  Immunology Who goes there? By Carla Nowosad How B cells assess risk in the intestine Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. 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