Graphical abstract

Highlights

► MYC controls up to 15% of all genes. ► MYC activates gene expression by recruiting multiple cofactors. ► A prime target of MYC is the C-terminal domain of polymerase II. ► MYC activates paused polymerase and promotes processivity.

Highlights

► NRDRA2, a novel isoform of the humanDHRS4gene, was identified in mRNA and protein. ► NRDRA2 localized in the nuclei. ► The nuclear localization signal in NRDRA2 was confirmed to be functional. ► NRDRA2 lost the catalytic activity as a retinol dehydrogenase/reductase.

Highlights

► We investigated the association of four microRNA polymorphisms in Korean RSA patients. ► We could find the relation between four microRNA polymorphisms and occurrence of RSA. ► Four microRNA polymorphisms may contribute to incidence of RSA.

Highlights

► We identify two polymorphic regions in the C-terminal of avian vasotocin receptor. ► Some species of passerine birds exhibit intra-specific polymorphism. ► The level of genetic variation differs between passerine and non-passerine birds. ► Indels affect the pattern of predicted palmitoylation sites in C-terminus of AVT2R.

Highlights

► Isolation of homeologous cellulose syntheases 2 from allotetraploid cotton. ► Evolutionary studies of GhCesA2 homeologs between diploid and polyploid cottons. ► Characterization of temporal and spatial expression patterns of GhCesA2 homeologs.

Highlights

► Novel associations of rs2943634 (2q36.3) with ischemic stroke and adiponectin. ► Association between rs2943634 and high density lipoprotein cholesterol. ► We subscribe lack of association between rs2943634 and myocardial infarction.

Highlights

► AM fungal symbiosis with 80% plant roots used as alternatives for P fertilizers.► Trichoderma harzianumis a helper organism for symbiosis, signaling pathway??. ► To extend this association to all plants, elucidation of genes/proteins is necessary. ► mRNA DD approach, detect genes in plant induced byTrichodermaexcretes. ► Major finding, over-expression AM gene, contribution in initiation of colonization.

Highlights

► Analysis of the mitogenome ofGomphocerus tibetanusUvarov, 1935

Highlights

► The commercial kits used Column based silica not suitable for the recovery of RNA from the biofilm positive bacteria. ► We have improved a low-cost effective method of cell wall disruption for the potential biofilm pathogenS. aureus, without the need for a bead glass or the enzyme, which employs the use of phenol protocol with only three steps. ► This method can be used in conjunction with the commercial RNA kits that use silica-based column and yields high concentration and highest integrity of recovered RNA.

Highlights

►We cloned the full-length cDNA of sheep α-TTP gene from sheep liver for the first time. ►Dietary vitamin E levels did not affect α-TTP mRNA expression significantly. ►Sheep α-TTP protein was lower when supplemented with high vitamin E levels while it was higher in response to low dietary vitamin E levels.

Highlights

► Association of myostatin gene SNPs with obesity was performed in Chinese people. ► Total 11 SNPs in MSTN gene were identified. ► The A allele carriers in rs3791783 have an increased susceptibility to obesity. ► Participants with AA genotype in rs3791783 will have much higher BW, BMI and WC.