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Current Issue of Nature


Current Issue : Nature

Current Issue

Volume 546 Number 7656 pp7-180

1 June 2017

About the cover

The diversity of life on Earth is breathtaking — but it is also under serious threat. Potentially beneficial relationships, such as that between the zebra and red-billed oxpecker shown on the cover, abound, but other, potently destructive relationships are challenging species, habitats and ecosystems as never before. In this week’s issue, Nature explores some of the key themes in biodiversity and conservation. The Insight delves deeply into the processes that shape and sustain the rich variety of life on the planet and the accelerating rate at which this diversity is being eroded. Crucially, it also explores ways to stave off further losses and protect ecosystems as well as the myriad benefits of such conservation efforts. Elsewhere, a News Feature reveals how thinking about functional units in ecosystems can be more useful than simply cataloguing species. Two Comment articles tackle the issues of land access and the parlous state of taxonomy. And two Letters consider how diversity influences ecosystem functioning and the scope for disproportionate gains in biodiversity from relatively small expansions in protected areas. There are clear gains to be made by shrewd policymaking and local engagement — but the clock is ticking. Cover image: Richard Du Toit/Minden/NGC

This Week

Editorials

Top

World View

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Research Highlights

Top

Seven Days

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    News in Focus

    Feature

    Top

    comment

    Books and Arts

    Top
    • Genome editing: That's the way the CRISPR crumbles

      Nathaniel Comfort finds heroism but little nuance in Jennifer Doudna's account of her co-discovery.

      • Review of A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution
        Jennifer A. Doudna & Samuel H. Sternberg
    • Books in brief

      Barbara Kiser reviews five of the week's best science picks.

    • Art: Under Mona Lisa's smile

      Philip Ball is intrigued by an analysis of Leonardo's iconic painting.

      • Review of Mona Lisa: The People and the Painting
        Martin Kemp & Giuseppe Pallanti

    Careers

    Features

    Top

    Columns

    Top
    • Paths of glory

      Look past the academia treadmill, says Ushma S. Neill.

      • Ushma S Neill

    naturejobs job listings and advertising features

    Futures

    Specials

    Toolbox

    Top
    • Software simplified

      Containerization technology takes the hassle out of setting up software and can boost the reproducibility of data-driven research.

      • Andrew Silver

    Insight: Biodiversity

    Insight: Biodiversity

    research

    Articles

    Top
    • Blocking FSH induces thermogenic adipose tissue and reduces body fat

      • Peng Liu
      • Yaoting Ji
      • Tony Yuen
      • Elizabeth Rendina-Ruedy
      • Victoria E. DeMambro
      • Samarth Dhawan
      • Wahid Abu-Amer
      • Sudeh Izadmehr
      • Bin Zhou
      • Andrew C. Shin
      • Rauf Latif
      • Priyanthan Thangeswaran
      • Animesh Gupta
      • Jianhua Li
      • Valeria Shnayder
      • Samuel T. Robinson
      • Yue Eric Yu
      • Xingjian Zhang
      • Feiran Yang
      • Ping Lu
      • Yu Zhou
      • Ling-Ling Zhu
      • Douglas J. Oberlin
      • Terry F. Davies
      • Michaela R. Reagan
      • Aaron Brown
      • T. Rajendra Kumar
      • Solomon Epstein
      • Jameel Iqbal
      • Narayan G. Avadhani
      • Maria I. New
      • Henrik Molina
      • Jan B. van Klinken
      • Edward X. Guo
      • Christoph Buettner
      • Shozeb Haider
      • Zhuan Bian
      • Li Sun
      • Clifford J. Rosen
      • Mone Zaidi

      An antibody against the pituitary hormone Fsh reduces adiposity and increases thermogenesis in ovariectomized mice or mice fed a high-fat diet.

    • Ensemble cryo-EM elucidates the mechanism of translation fidelity

      • Anna B. Loveland
      • Gabriel Demo
      • Nikolaus Grigorieff
      • Andrei A. Korostelev

      Structural ensembles of the 70S ribosome bound to cognate or near-cognate charged tRNAs in complex with EF-Tu illustrate the crucial role of the nucleotide G530 in decoding of mRNA, and demonstrate that translational fidelity results from direct control of GTPase by the decoding centre.

    • Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

      • Yi-Lynn Liang
      • Maryam Khoshouei
      • Mazdak Radjainia
      • Yan Zhang
      • Alisa Glukhova
      • Jeffrey Tarrasch
      • David M. Thal
      • Sebastian G. B. Furness
      • George Christopoulos
      • Thomas Coudrat
      • Radostin Danev
      • Wolfgang Baumeister
      • Laurence J. Miller
      • Arthur Christopoulos
      • Brian K. Kobilka
      • Denise Wootten
      • Georgios Skiniotis
      • Patrick M. Sexton

      Volta phase-plate cryo-electron microscopy reveals the structure of the full-length calcitonin receptor in complex with its peptide ligand and Gαsβγ.

      See also

    Letters

    Top
    • Electric-field control of tri-state phase transformation with a selective dual-ion switch

      • Nianpeng Lu
      • Pengfei Zhang
      • Qinghua Zhang
      • Ruimin Qiao
      • Qing He
      • Hao-Bo Li
      • Yujia Wang
      • Jingwen Guo
      • Ding Zhang
      • Zheng Duan
      • Zhuolu Li
      • Meng Wang
      • Shuzhen Yang
      • Mingzhe Yan
      • Elke Arenholz
      • Shuyun Zhou
      • Wanli Yang
      • Lin Gu
      • Ce-Wen Nan
      • Jian Wu
      • Yoshinori Tokura
      • Pu Yu

      Materials are described here that can change their crystalline phase in response to the electrically controlled insertion or extraction of oxygen and hydrogen ions, giving rise to three distinct phases with different optical, electrical and magnetic properties.

      See also
    • Femtosecond response of polyatomic molecules to ultra-intense hard X-rays

      • A. Rudenko
      • L. Inhester
      • K. Hanasaki
      • X. Li
      • S. J. Robatjazi
      • B. Erk
      • R. Boll
      • K. Toyota
      • Y. Hao
      • O. Vendrell
      • C. Bomme
      • E. Savelyev
      • B. Rudek
      • L. Foucar
      • S. H. Southworth
      • C. S. Lehmann
      • B. Kraessig
      • T. Marchenko
      • M. Simon
      • K. Ueda
      • K. R. Ferguson
      • M. Bucher
      • T. Gorkhover
      • S. Carron
      • R. Alonso-Mori
      • J. E. Koglin
      • J. Correa
      • G. J. Williams
      • S. Boutet
      • L. Young
      • C. Bostedt
      • S.-K. Son
      • R. Santra
      • D. Rolles

      Upon exposure to ultra-intense, hard X-ray pulses, polyatomic molecules containing one heavy atom reach a much higher degree of ionization than do individual heavy atoms, contrary to previous assumptions.

    • Extreme hydrothermal conditions at an active plate-bounding fault

      • Rupert Sutherland
      • John Townend
      • Virginia Toy
      • Phaedra Upton
      • Jamie Coussens
      • Michael Allen
      • Laura-May Baratin
      • Nicolas Barth
      • Leeza Becroft
      • Carolin Boese
      • Austin Boles
      • Carolyn Boulton
      • Neil G. R. Broderick
      • Lucie Janku-Capova
      • Brett M. Carpenter
      • Bernard Célérier
      • Calum Chamberlain
      • Alan Cooper
      • Ashley Coutts
      • Simon Cox
      • Lisa Craw
      • Mai-Linh Doan
      • Jennifer Eccles
      • Dan Faulkner
      • Jason Grieve
      • Julia Grochowski
      • Anton Gulley
      • Arthur Hartog
      • Jamie Howarth
      • Katrina Jacobs
      • Tamara Jeppson
      • Naoki Kato
      • Steven Keys
      • Martina Kirilova
      • Yusuke Kometani
      • Rob Langridge
      • Weiren Lin
      • Timothy Little
      • Adrienn Lukacs
      • Deirdre Mallyon
      • Elisabetta Mariani
      • Cécile Massiot
      • Loren Mathewson
      • Ben Melosh
      • Catriona Menzies
      • Jo Moore
      • Luiz Morales
      • Chance Morgan
      • Hiroshi Mori
      • Andre Niemeijer
      • Osamu Nishikawa
      • David Prior
      • Katrina Sauer
      • Martha Savage
      • Anja Schleicher
      • Douglas R. Schmitt
      • Norio Shigematsu
      • Sam Taylor-Offord
      • Damon Teagle
      • Harold Tobin
      • Robert Valdez
      • Konrad Weaver
      • Thomas Wiersberg
      • Jack Williams
      • Nick Woodman
      • Martin Zimmer

      Extreme temperatures and fluid pressures are measured, and their causes modelled, in a borehole into the Alpine Fault, where an earthquake rupture is expected within the next few decades.

    • Leaf bacterial diversity mediates plant diversity and ecosystem function relationships

      • Isabelle Laforest-Lapointe
      • Alain Paquette
      • Christian Messier
      • Steven W. Kembel

      A tree biodiversity and ecosystem function experiment shows that leaf bacterial diversity is positively related to plant community productivity, and explains a portion of the variation in productivity that would otherwise be attributed to plant diversity and functional traits.

    • The sunflower genome provides insights into oil metabolism, flowering and Asterid evolutionOpen

      • Hélène Badouin
      • Jérôme Gouzy
      • Christopher J. Grassa
      • Florent Murat
      • S. Evan Staton
      • Ludovic Cottret
      • Christine Lelandais-Brière
      • Gregory L. Owens
      • Sébastien Carrère
      • Baptiste Mayjonade
      • Ludovic Legrand
      • Navdeep Gill
      • Nolan C. Kane
      • John E. Bowers
      • Sariel Hubner
      • Arnaud Bellec
      • Aurélie Bérard
      • Hélène Bergès
      • Nicolas Blanchet
      • Marie-Claude Boniface
      • Dominique Brunel
      • Olivier Catrice
      • Nadia Chaidir
      • Clotilde Claudel
      • Cécile Donnadieu
      • Thomas Faraut
      • Ghislain Fievet
      • Nicolas Helmstetter
      • Matthew King
      • Steven J. Knapp
      • Zhao Lai
      • Marie-Christine Le Paslier
      • Yannick Lippi
      • Lolita Lorenzon
      • Jennifer R. Mandel
      • Gwenola Marage
      • Gwenaëlle Marchand
      • Elodie Marquand
      • Emmanuelle Bret-Mestries
      • Evan Morien
      • Savithri Nambeesan
      • Thuy Nguyen
      • Prune Pegot-Espagnet
      • Nicolas Pouilly
      • Frances Raftis
      • Erika Sallet
      • Thomas Schiex
      • Justine Thomas
      • Céline Vandecasteele
      • Didier Varès
      • Felicity Vear
      • Sonia Vautrin
      • Martin Crespi
      • Brigitte Mangin
      • John M. Burke
      • Jérôme Salse
      • Stéphane Muños
      • Patrick Vincourt
      • Loren H. Rieseberg
      • Nicolas B. Langlade

      A high-quality reference for the sunflower genome (Helianthus annuus L.) and analysis of gene networks involved in flowering time and oil metabolism provide a basis for nutritional exploitation and analyses of adaptation to climate change.

      See also
    • Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells

      • Alejandra Mendoza
      • Victoria Fang
      • Cynthia Chen
      • Madhavika Serasinghe
      • Akanksha Verma
      • James Muller
      • V. Sai Chaluvadi
      • Michael L. Dustin
      • Timothy Hla
      • Olivier Elemento
      • Jerry E. Chipuk
      • Susan R. Schwab

      The chemoattractant S1P is identified as an extrinsic factor that supports naive T cell survival, and acts via a signalling mechanism to maintain mitochondrial content and function.

    • Applying systems-level spectral imaging and analysis to reveal the organelle interactome

      • Alex M. Valm
      • Sarah Cohen
      • Wesley R. Legant
      • Justin Melunis
      • Uri Hershberg
      • Eric Wait
      • Andrew R. Cohen
      • Michael W. Davidson
      • Eric Betzig
      • Jennifer Lippincott-Schwartz

      Using confocal and lattice light sheet microscopy, the authors perform systems-level analysis of the organelle interactome in live cells, allowing them to visualize the frequency and locality of up to five-way interactions between different organelles.

      See also
    • CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

      • Jiyeon Kim
      • Zeping Hu
      • Ling Cai
      • Kailong Li
      • Eunhee Choi
      • Brandon Faubert
      • Divya Bezwada
      • Jaime Rodriguez-Canales
      • Pamela Villalobos
      • Yu-Fen Lin
      • Min Ni
      • Kenneth E. Huffman
      • Luc Girard
      • Lauren A. Byers
      • Keziban Unsal-Kacmaz
      • Christopher G. Peña
      • John V. Heymach
      • Els Wauters
      • Johan Vansteenkiste
      • Diego H. Castrillon
      • Benjamin P. C. Chen
      • Ignacio Wistuba
      • Diether Lambrechts
      • Jian Xu
      • John D. Minna
      • Ralph J. DeBerardinis

      In human cell lines with mutant KRAS and loss of LKB1, CPS1 expression correlates inversely with LKB1 expression; silencing CPS1 in these cells induces DNA damage and cell death as a result of pyrimidine depletion rather than ammonia toxicity.