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Current Issue of Nature


Volume 563 Issue 7732, 22 November 2018

Volume 563 Issue 7732, 22 November 2018

Volume 563 Issue 7732

A first forflight

For more than 100 years, aeroplanes have taken flight thanks to engine-based propellers and turbines, mostly powered by fossil fuels. In this week’s issue, Steven Barrett and his colleagues reveal an alternative: a plane powered by a near-silent engine that has no moving parts. Solid-state propulsion systems use electric fields to ionize the molecules in the air, which then collide with neutral molecules, resulting in an ionic wind that generates thrust. It had been thought that thrust-to-power limitations would prevent such systems from propelling planes but the researchers demonstrate this is not so with the sustained flight of a solid-state aeroplane. Weighing 2.45 kilograms, the plane has a 5-metre wingspan and carries a battery stack and power converter that produces around 500 watts. In the test flights, the plane achieved a thrust-to-power ratio comparable to that of a jet engine, although the overall efficiency was lower. This proof of concept opens up possibilities for electroaerodynamic propulsion, which could lead to quieter, low-emissions aeroplanes.

Cover image: Christina Y. He

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  • Perspective |

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    • P. M. Pattison
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  • Articles

  • Article | | open

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    • Benjamin J. Matthews
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    • , Igor Antoshechkin
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  • Letters

  • Letter |

    A multi-qubit mixed-species register is used for repeated correlation measurements using conditional feedback to stabilize two-qubit subspaces and Bell states, achieving up to 50 sequential measurements with negligible crosstalk.

    • V. Negnevitsky
    • , M. Marinelli
    • , K. K. Mehta
    • , H.-Y. Lo
    • , C. Flühmann
    •  & J. P. Home
  • Letter |

    A solid-state propulsion system can sustain powered flight, as demonstrated by an electroaerodynamically propelled heavier-than-air aeroplane.

    • Haofeng Xu
    • , Yiou He
    • , Kieran L. Strobel
    • , Christopher K. Gilmore
    • , Sean P. Kelley
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    • , Mark R. Woolston
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  • Letter |

    Organic light-emitting devices containing radical emitters can achieve an efficiency of 27 per cent at deep-red and infrared wavelengths based on the excitation of spin doublets, rather than singlet or triplet states.

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    • , Shengzhi Dong
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    • , Haoqing Guo
    • , Yingxin Chen
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    • , Xiongjun Liu
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    • , Suihe Jiang
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    • , Yidong Wu
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    • , Paraskevas Kontis
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    • , Houwen Chen
    • , Hongtao Wang
    • , Jiabin Liu
    • , Ke An
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    •  & Zhaoping Lu
  • Letter |

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    • Jasmina Wiemann
    • , Tzu-Ruei Yang
    •  & Mark A. Norell
  • Letter |

    New World hantaviruses—which cause a severe human respiratory disease—use surface glycoproteins to bind to the human protocadherin-1 protein and enter endothelial cells in vitro; depleting protocadherin-1 in Syrian golden hamsters largely protects against disease.

    • Rohit K. Jangra
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    • , Lucas T. Jae
    • , Lara M. Kleinfelter
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    • , Sarah L. Barker
    • , Pablo Guardado-Calvo
    • , Gleyder Román-Sosa
    • , M. Eugenia Dieterle
    • , Ana I. Kuehne
    • , Nicolás A. Muena
    • , Ariel S. Wirchnianski
    • , Elisabeth K. Nyakatura
    • , J. Maximilian Fels
    • , Melinda Ng
    • , Eva Mittler
    • , James Pan
    • , Sushma Bharrhan
    • , Anna Z. Wec
    • , Jonathan R. Lai
    • , Sachdev S. Sidhu
    • , Nicole D. Tischler
    • , Félix A. Rey
    • , Jason Moffat
    • , Thijn R. Brummelkamp
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    • , John M. Dye
    •  & Kartik Chandran
  • Letter |

    Tetrahydrobiopterin (BH4) is an enzyme co-factor that is involved in the nervous system; it is shown here to also function in T cell activation and proliferation, with roles in autoimmunity, allergic inflammation and cancer.

    • Shane J. F. Cronin
    • , Corey Seehus
    • , Adelheid Weidinger
    • , Sebastien Talbot
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    • , Markus Seifert
    • , Yann Pierson
    • , Eileen McNeill
    • , Maria Serena Longhi
    • , Bruna Lenfers Turnes
    • , Taras Kreslavsky
    • , Melanie Kogler
    • , David Hoffmann
    • , Melita Ticevic
    • , Débora da Luz Scheffer
    • , Luigi Tortola
    • , Domagoj Cikes
    • , Alexander Jais
    • , Manu Rangachari
    • , Shuan Rao
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    • , Maria Novatchkova
    • , Martin Aichinger
    • , Lee Barrett
    • , Alban Latremoliere
    • , Gerald Wirnsberger
    • , Guenther Lametschwandtner
    • , Meinrad Busslinger
    • , Stephen Zicha
    • , Alexandra Latini
    • , Simon C. Robson
    • , Ari Waisman
    • , Nick Andrews
    • , Michael Costigan
    • , Keith M. Channon
    • , Guenter Weiss
    • , Andrey V. Kozlov
    • , Mark Tebbe
    • , Kai Johnsson
    • , Clifford J. Woolf
    •  & Josef M. Penninger
  • Letter |

    Mice with whole-body or liver-specific deletion of Atg7 release circulating arginase I and have reduced levels of serum arginine, which impairs the growth of allografted arginine-auxotrophic tumours.

    • Laura Poillet-Perez
    • , Xiaoqi Xie
    • , Le Zhan
    • , Yang Yang
    • , Daniel W. Sharp
    • , Zhixian Sherrie Hu
    • , Xiaoyang Su
    • , Anurag Maganti
    • , Cherry Jiang
    • , Wenyun Lu
    • , Haiyan Zheng
    • , Marcus W. Bosenberg
    • , Janice M. Mehnert
    • , Jessie Yanxiang Guo
    • , Edmund Lattime
    • , Joshua D. Rabinowitz
    •  & Eileen White
  • Letter |

    POLAR, identified in a survey of the protein interactome of BRASSINOSTEROID INSENSITIVE 2 in Arabidopsis thaliana, has a key role in coordinating cell polarity and enabling asymmetric cell division.

    • Anaxi Houbaert
    • , Cheng Zhang
    • , Manish Tiwari
    • , Kun Wang
    • , Alberto de Marcos Serrano
    • , Daniel V. Savatin
    • , Mounashree J. Urs
    • , Miroslava K. Zhiponova
    • , Gustavo E. Gudesblat
    • , Isabelle Vanhoutte
    • , Dominique Eeckhout
    • , Sjef Boeren
    • , Mansour Karimi
    • , Camilla Betti
    • , Thomas Jacobs
    • , Carmen Fenoll
    • , Montaña Mena
    • , Sacco de Vries
    • , Geert De Jaeger
    •  & Eugenia Russinova
  • Letter |

    An immunoprecipitation-based protocol is developed to analyse DNA methylation in small quantities of circulating cell-free DNA, and can detect and classify cancers in plasma samples from several tumour types.

    • Shu Yi Shen
    • , Rajat Singhania
    • , Gordon Fehringer
    • , Ankur Chakravarthy
    • , Michael H. A. Roehrl
    • , Dianne Chadwick
    • , Philip C. Zuzarte
    • , Ayelet Borgida
    • , Ting Ting Wang
    • , Tiantian Li
    • , Olena Kis
    • , Zhen Zhao
    • , Anna Spreafico
    • , Tiago da Silva Medina
    • , Yadon Wang
    • , David Roulois
    • , Ilias Ettayebi
    • , Zhuo Chen
    • , Signy Chow
    • , Tracy Murphy
    • , Andrea Arruda
    • , Grainne M. O’Kane
    • , Jessica Liu
    • , Mark Mansour
    • , John D. McPherson
    • , Catherine O’Brien
    • , Natasha Leighl
    • , Philippe L. Bedard
    • , Neil Fleshner
    • , Geoffrey Liu
    • , Mark D. Minden
    • , Steven Gallinger
    • , Anna Goldenberg
    • , Trevor J. Pugh
    • , Michael M. Hoffman
    • , Scott V. Bratman
    • , Rayjean J. Hung
    •  & Daniel D. De Carvalho
  • Letter |

    The carboxy terminus of human UDP-α-d-glucose-6-dehydrogenase is structurally disordered, but has sequence-independent effects on the conformation of the enzyme and binding of an allosteric inhibitor, suggesting a reason for the persistence of intrinsically disordered peptide segments in the proteome.

    • Nicholas D. Keul
    • , Krishnadev Oruganty
    • , Elizabeth T. Schaper Bergman
    • , Nathaniel R. Beattie
    • , Weston E. McDonald
    • , Renuka Kadirvelraj
    • , Michael L. Gross
    • , Robert S. Phillips
    • , Stephen C. Harvey
    •  & Zachary A. Wood

Amendments & Corrections

Nature Outlook

  • Nature Outlook |

    Skin

    Skin is the body’s largest organ and first line of defence against disease and injury. Researchers have been working to unlock skin’s secrets so as to help heal, treat and mimic this essential barrier
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