Subject: PLOS Biology Volume 15(7) July 2017 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit

ADVERTISEMENT

Manage Preferences >

New Articles in PLOS Biology

PUBLISHED: July 01, 2017 to July 31, 2017

Primers

The costs of saving nature: Does it make "cents"?

This Primer discusses how the economic valuation of ecosystem services can be used to choose sites for either land conservation or development, highlighting a recent study in PLOS Biology. Read the associated Research Article here.

Multiple visual objects are sampled sequentially

This Primer discusses a recent study which suggests that objects in visual scenes are sampled one-by-one rather than in parallel; this sampling is reflected by modulations of neuronal ~10-Hz oscillations. Read the associated Research Article here.

Bacterial deception of MAIT cells in a cloud of superantigen and cytokines

This Primer discusses recent findings which indicate that bacteria can hijack the function of the anti-bacterial lymphocytes known as mucosa-associated invariant T (MAIT) cells and leave them dead in the water. Read the associated Research Article here.

Research Matters

The selfish germ

In this Research Matters article, Andrew Read recalls how an analysis of incest in wasps revealed a way to improve human well-being.

Essays

Building the biomedical data science workforce

Data science in biomedicine is a field where the demand for the workforce far outweighs the supply; this article describes how the US National Institutes of Health has set about addressing the situation.

Genes, cells, and biobanks: Yes, there's still a consent problem

Issues associated with consent and the control of biomedical research samples in the context of biobanking continue to create significant legal and public perception challenges¦ and things could get worse.

Community Page

The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and Caenorhabditis elegans

This Community Page article tells you how to build your own fluorescence microscope and behavioural rig for less than 100 Euros using 3-D printed parts and off-the-shelf electronics.

Research Articles

RNA stores tau reversibly in complex coacervates

Tau protein binds tRNA in living cells, and under physiological conditions reversibly condenses to form complex liquid droplets that may be precursors for the formation of tau fibrils found in neurodegenerative diseases.

Hierarchical patterning modes orchestrate hair follicle morphogenesis

Hair follicle development involves establishing a hierarchy of patterning systems, whereby a patterning process driven by cell movement is subordinated to a signal-based reaction-diffusion mechanism.

Four simple rules that are sufficient to generate the mammalian blastocyst

A new model, in which four simple rules can produce a mammalian embryo and explain scaling, ensures developmental robustness while allowing evolution to play with stochasticity.

Dramatic and concerted conformational changes enable rhodocetin to block alpha 2beta 1 integrin selectively

A bifunctional snake venom protein from the Malayan pit viper Calloselasma rhodostoma blocks collagen mediated platelet aggregation, undergoing dramatic conformational changes as it binds alpha 2beta 1 integrin.

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

The receptor tyrosine kinase EphB undergoes ligand-dependent extracellular phosphorylation to regulate NMDA receptor synaptic localization and pathological pain in mice.

Seed size and its rate of evolution correlate with species diversification across angiosperms

A study of 30,000 species reveals that faster changing seed sizes are associated with increased rates of species formation across the angiosperm tree of life.

Global economic trade-offs between wild nature and tropical agriculture

A pan-tropical study reveals the spatial economic trade-offs between agricultural conversion and the loss of multiple ecosystem services, revealing opportunity and challenge areas for tropical conservation.

Neuronal synchrony and the relation between the blood-oxygen-level dependent response and the local field potential

A computational model of how neuronal population activity is translated into a metabolic response (the fMRI Blood Oxygen Level Dependent, or BOLD, signal) or an electrical measure (the ECoG local field potential), shows that the former emphasizes the total level of neuronal activity while the latter emphasizes neuronal synchrony.

Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus

Comparisons between two tardigrade species using high-quality genome sequences reveals a diversity of mechanisms for anhydrobiosis, a minor but important role for horizontal gene transfer, and unexpected evolutionary relationships to other phyla.

Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment

Combined single-cell morphometry and transcriptomics reveal that hematopoietic stem cells undergo a random fluctuating phase of variable length before committing to a given fate.

Short Reports

Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway

Anesthetic exposure in early childhood may cause lasting cognitive deficits. This study shows that isoflurane acts on the mTOR pathway to cause dendritic spine loss and learning deficits in mice.

Methods and Resources

A multiscale cerebral neurochemical connectome of the rat brain

ChemNetDB is a systematic, terminologically consistent open-access resource for the multi-scale neurochemical connectome of the rat brain, containing data from 34,464 animals.

Corrections

Correction: 1.2 million kids and counting'Mobile science laboratories drive student interest in STEM

Correction: Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

Correction: A latitudinal phylogeographic diversity gradient in birds

ADVERTISEMENT

Want to hear more from PLOS? Access our full list of journal alerts and create unique updates through your PLOS Account

   REGISTER NOW   

    SUBMIT YOUR RESEARCH    

You are receiving this email because you opted to receive updates from PLOS Biology

UNSUBSCRIBE | CONTACT US | SUBMIT

All works published in PLOS journals are open access, distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright is retained by the author. You can change or discontinue your alerts at any time by modifying your profile.

Public Library of Science
1160 Battery St. Suite 225
San Francisco, CA 94111, US

--jh3efjF22eUL=_?:--