Subject: PLOS Computational Biology Volume 14(2) February 2018 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit

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New Articles in PLOS Computational Biology

PUBLISHED: February 01, 2018 to February 28, 2018

Editorial

Ten simple rules for writing a popular science book

Message from ISCB

The development and application of bioinformatics core competencies to improve bioinformatics training and education

Education

Quick tips for creating effective and impactful biological pathways using the Systems Biology Graphical Notation

Research Articles

Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation

A computational framework for cortical microtubule dynamics in realistically shaped plant cells

Simulation enabled search for explanatory mechanisms of the fracture healing process

A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombination

Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach

A maximum-entropy model for predicting chromatin contacts

Membrane perturbing properties of toxin mycolactone from Mycobacterium ulcerans

Interpretation of correlated neural variability from models of feed-forward and recurrent circuits

Imaging of neural oscillations with embedded inferential and group prevalence statistics

A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

The feasibility of equilibria in large ecosystems: A primary but neglected concept in the complexity-stability debate

Spike and burst coding in thalamocortical relay cells

History dependence in insect flight decisions during odor tracking

Electrical receptive fields of retinal ganglion cells: Influence of presynaptic neurons

Heritable tumor cell division rate heterogeneity induces clonal dominance

Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains

Hub connectivity, neuronal diversity, and gene expression in the Caenorhabditis elegans connectome

Recognition of sites of functional specialisation in all known eukaryotic protein kinase families

Self-crowding of AMPA receptors in the excitatory postsynaptic density can effectuate anomalous receptor sub-diffusion

Examining the controllability of sepsis using genetic algorithms on an agent-based model of systemic inflammation

Life cycle synchronization is a viral drug resistance mechanism

A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism

Modeling the interactions of sense and antisense Period transcripts in the mammalian circadian clock network

A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts

A model of risk and mental state shifts during social interaction

Optimizing homeostatic cell renewal in hierarchical tissues

Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield

Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents

Integrating linear optimization with structural modeling to increase HIV neutralization breadth

A stochastic and dynamical view of pluripotency in mouse embryonic stem cells

In silico analysis of antibiotic-induced Clostridium difficile infection: Remediation techniques and biological adaptations

Control fast or control smart: When should invading pathogens be controlled?

Prediction of infectious disease epidemics via weighted density ensembles

Exploiting the geometry of the solution space to reduce sensitivity to neuromotor noise

The self-organization of plant microtubules inside the cell volume yields their cortical localization, stable alignment, and sensitivity to external cues

Association between expression of random gene sets and survival is evident in multiple cancer types and may be explained by sub-classification

Memory functions reveal structural properties of gene regulatory networks

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks

Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats

PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems

Mathematical modelling of the antibiotic-induced morphological transition of Pseudomonas aeruginosa

Multiscale modeling of layer formation in epidermis

Differential tissue growth and cell adhesion alone drive early tooth morphogenesis: An ex vivo and in silico study

Genetic programming based models in plant tissue culture: An addendum to traditional statistical approach

Ligand-induced perturbation of the HIF-2alpha :ARNT dimer dynamics

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