Subject: PLOS Computational Biology Volume 15(7) July 2019 Content-Type: text/html; charset="us-ascii" Content-Transfer-Encoding: 7bit


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New Articles in PLOS Computational Biology

PUBLISHED: July 01, 2019 to July 31, 2019


Ten simple rules for writing and sharing computational analyses in Jupyter Notebooks

Ten simple rules for giving an effective academic job talk


Think: Theory for Africa


Machine and deep learning meet genome-scale metabolic modeling

Research Articles

DART-ID increases single-cell proteome coverage

The invasion of de-differentiating cancer cells into hierarchical tissues

Molecular noise of innate immunity shapes bacteria-phage ecologies

Cross-species functional modules link proteostasis to human normal aging

Modelling the mechanics of exploration in larval Drosophila

Disease gene prediction for molecularly uncharacterized diseases

With an eye on uncertainty: Modelling pupillary responses to environmental volatility

Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference

Human online adaptation to changes in prior probability

Remarkable structural transformations of actin bundles are driven by their initial polarity, motor activity, crosslinking, and filament treadmilling

ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages

Identifying determinants of persistent MRSA bacteremia using mathematical modeling

Modeling the daily rhythm of human pain processing in the dorsal horn

Sensorimotor maps can be dynamically calibrated using an adaptive-filter model of the cerebellum

PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting

Dimensionality in recurrent spiking networks: Global trends in activity and local origins in connectivity

Information-theoretic analysis of multivariate single-cell signaling responses

Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas

Large vessels as a tree of transmission lines incorporated in the CircAdapt whole-heart model: A computational tool to examine heart-vessel interaction

Reservoir computing model of prefrontal cortex creates novel combinations of previous navigation sequences from hippocampal place-cell replay with spatial reward propagation

Analyzing pharmacological intervention points: A method to calculate external stimuli to switch between steady states in regulatory networks

Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential

From skylight input to behavioural output: A computational model of the insect polarised light compass

Propagation of orientation selectivity in a spiking network model of layered primary visual cortex

Primacy coding facilitates effective odor discrimination when receptor sensitivities are tuned

Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions

Recombinant vector vaccine evolution

Assessing key decisions for transcriptomic data integration in biochemical networks

beta -Methylamino-L-alanine substitution of serine in SOD1 suggests a direct role in ALS etiology

Modeling human intuitions about liquid flow with particle-based simulation

Aberrant DNA methylation defines isoform usage in cancer, with functional implications

Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data

Why do eukaryotic proteins contain more intrinsically disordered regions?

Ensemble of decision tree reveals potential miRNA-disease associations

Mathematical model predicts anti-adhesion-antibiotic-debridement combination therapies can clear an antibiotic resistant infection

Where did you come from, where did you go: Refining metagenomic analysis tools for horizontal gene transfer characterisation

Biophysics and population size constrains speciation in an evolutionary model of developmental system drift

A case study in the functional consequences of scaling the sizes of realistic cortical models

Syntrophy emerges spontaneously in complex metabolic systems

Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers

Foraging as an evidence accumulation process

Heterogeneous susceptibility to rotavirus infection and gastroenteritis in two birth cohort studies: Parameter estimation and epidemiological implications

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

The impact of DNA methylation on the cancer proteome

A computational framework for the morpho-elastic development of molluskan shells by surface and volume growth

Depressive symptoms are associated with blunted reward learning in social contexts

Frontal cortex tracks surprise separately for different sensory modalities but engages a common inhibitory control mechanism

A model for the origin and development of visual orientation selectivity

Robustness of respiratory rhythm generation across dynamic regimes

Identifying important parameters in the inflammatory process with a mathematical model of immune cell influx and macrophage polarization


Correction: From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm

Correction: Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources

Correction: Temporal Gillespie algorithm: Fast simulation of contagion processes on time-varying networks


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