Proceedings of the National Academy of Sciences: 116 (44)

New Research In

October 29, 2019; vol. 116 no. 44

This Week in PNAS

You have access
In This Issue
PNAS October 29, 2019 116 (44) 21951-21952; https://doi.org/10.1073/iti4419116

Science and Culture

How science intersects with culture.

You have access
Science and Culture: Why “seeing” some scientific phenomena entails a touch of artistry and a dash of interpretation
Front Matter
Amy McDermott

PNAS October 29, 2019 116 (44) 21953-21956; https://doi.org/10.1073/pnas.1916741116

Core Concepts

A brief introduction to emerging topics in science.

You have access
Core Concept: Emerging science of chronotherapy offers big opportunities to optimize drug delivery
Front Matter
David Adam

PNAS October 29, 2019 116 (44) 21957-21959; https://doi.org/10.1073/pnas.1916118116

Commentaries

You have access
Mechanosensing tensile solid stresses
Lance L. Munn and Hadi T. Nia

PNAS October 29, 2019 116 (44) 21960-21962; first published October 16, 2019. https://doi.org/10.1073/pnas.1916115116
You have access
Linking long noncoding RNA to drug resistance
Michael J. Smallegan and John L. Rinn

PNAS October 29, 2019 116 (44) 21963-21965; first published October 10, 2019. https://doi.org/10.1073/pnas.1915690116
You have access
Tar adhesives, Neandertals, and the tyranny of the discontinuous mind
João Zilhão

PNAS October 29, 2019 116 (44) 21966-21968; first published October 21, 2019. https://doi.org/10.1073/pnas.1916116116
You have access
T cell antigen recognition: Evolution-driven affinities
Rémy Bosselut

PNAS October 29, 2019 116 (44) 21969-21971; first published October 14, 2019. https://doi.org/10.1073/pnas.1916129116

Letters

You have access
Sighted people’s language is not helpful for blind individuals’ acquisition of typical animal colors
Markus Ostarek, Jeroen van Paridon, and Guillermo Montero-Melis

PNAS October 29, 2019 116 (44) 21972-21973; first published October 15, 2019. https://doi.org/10.1073/pnas.1912302116
You have access
Reply to Ostarek et al.: Language, but not co-occurrence statistics, is useful for learning animal appearance
Judy S. Kim, Giulia V. Elli, and Marina Bedny

PNAS October 29, 2019 116 (44) 21974-21975; first published October 15, 2019. https://doi.org/10.1073/pnas.1912854116
You have access
Not even noninvasive cell-free DNA can rescue preimplantation genetic testing
Norbert Gleicher and David H. Barad

PNAS October 29, 2019 116 (44) 21976-21977; first published October 1, 2019. https://doi.org/10.1073/pnas.1911710116
You have access
Reply to Gleicher and Barad: Noninvasive preimplantation genetic testing may provide the solution to the problem of embryo mosaicism
Lei Huang, Sijia Lu, Catherine Racowsky, and X. Sunney Xie

PNAS October 29, 2019 116 (44) 21978-21979; first published October 1, 2019. https://doi.org/10.1073/pnas.1912042116

Brief Report

Open Access
Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host
William J. Perry, Jeffrey M. Spraggins, Jessica R. Sheldon, Caroline M. Grunenwald, David E. Heinrichs, James E. Cassat, Eric P. Skaar, and Richard M. Caprioli

PNAS October 29, 2019 116 (44) 21980-21982; first published October 14, 2019. https://doi.org/10.1073/pnas.1913991116

Physical Sciences

Applied Mathematics
- You have access
  Uniformly accurate machine learning-based hydrodynamic models for kinetic equations
  Jiequn Han, Chao Ma, Zheng Ma, and Weinan E
  
  PNAS October 29, 2019 116 (44) 21983-21991; first published October 16, 2019. https://doi.org/10.1073/pnas.1909854116
Applied Physical Sciences
- You have access
  Carrier localization in perovskite nickelates from oxygen vacancies
  Michele Kotiuga, Zhen Zhang, Jiarui Li, Fanny Rodolakis, Hua Zhou, Ronny Sutarto, Feizhou He, Qi Wang, Yifei Sun, Ying Wang, Neda Alsadat Aghamiri, Steven Bennett Hancock, Leonid P. Rokhinson, David P. Landau, Yohannes Abate, John W. Freeland, Riccardo Comin, Shriram Ramanathan, and Karin M. Rabe
  
  PNAS October 29, 2019 116 (44) 21992-21997; first published October 14, 2019. https://doi.org/10.1073/pnas.1910490116
- You have access
  Synergistic boost of output power density and efficiency in In-Li–codoped SnTe
  Fengkai Guo, Haijun Wu, Jianbo Zhu, Honghao Yao, Yang Zhang, Bo Cui, Qian Zhang, Bo Yu, Stephen J. Pennycook, Wei Cai, Ching-Wu Chu, and Jiehe Sui
  
  PNAS October 29, 2019 116 (44) 21998-22003; first published October 14, 2019. https://doi.org/10.1073/pnas.1911085116
Biophysics and Computational Biology
- You have access
  Cell mechanosensing is regulated by substrate strain energy rather than stiffness
  From the Cover
  
  Valeria Panzetta, Sabato Fusco, and Paolo A. Netti
  
  PNAS October 29, 2019 116 (44) 22004-22013; first published September 30, 2019. https://doi.org/10.1073/pnas.1904660116
- You have access
  4D electron microscopy of T cell activation
  Yue Lu, Byung-Kuk Yoo, Alphonsus H. C. Ng, Jungwoo Kim, Sinchul Yeom, Jau Tang, Milo M. Lin, Ahmed H. Zewail, and James R. Heath
  
  PNAS October 29, 2019 116 (44) 22014-22019; first published October 14, 2019. https://doi.org/10.1073/pnas.1914078116
- You have access
  Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes
  From the Cover
  
  Aritro Nath, Eunice Y. T. Lau, Adam M. Lee, Paul Geeleher, William C. S. Cho, and R. Stephanie Huang
  
  PNAS October 29, 2019 116 (44) 22020-22029; first published September 23, 2019. https://doi.org/10.1073/pnas.1909998116
- Open Access
  Fundamental helical geometry consolidates the plant photosynthetic membrane
  Yuval Bussi, Eyal Shimoni, Allon Weiner, Ruti Kapon, Dana Charuvi, Reinat Nevo, Efi Efrati, and Ziv Reich
  
  PNAS October 29, 2019 116 (44) 22366-22375; first published October 14, 2019. https://doi.org/10.1073/pnas.1905994116
Chemistry
- You have access
  Electrostatic shape control of a charged molecular membrane from ribbon to scroll
  Changrui Gao, Sumit Kewalramani, Dulce Maria Valencia, Honghao Li, Joseph M. McCourt, Monica Olvera de la Cruz, and Michael J. Bedzyk
  
  PNAS October 29, 2019 116 (44) 22030-22036; first published October 14, 2019. https://doi.org/10.1073/pnas.1913632116
- You have access
  A relatively wide-bandgap and air-stable donor polymer for fabrication of efficient semitransparent and tandem organic photovoltaics
  Mohammad Mahdi Tavakoli, Riccardo Po, Gabriele Bianchi, Alessandra Cominetti, Chiara Carbonera, Nadia Camaioni, Francesca Tinti, and Jing Kong
  
  PNAS October 29, 2019 116 (44) 22037-22043; first published October 16, 2019. https://doi.org/10.1073/pnas.1907495116
- You have access
  Computationally generated maps of surface structures and catalytic activities for alloy phase diagrams
  Liang Cao, Le Niu, and Tim Mueller
  
  PNAS October 29, 2019 116 (44) 22044-22051; first published October 14, 2019. https://doi.org/10.1073/pnas.1910724116
Earth, Atmospheric, and Planetary Sciences
- You have access
  Ion exchange selectivity in clay is controlled by nanoscale chemical–mechanical coupling
  Michael L. Whittaker, Laura N. Lammers, Sergio Carrero, Benjamin Gilbert, and Jillian F. Banfield
  
  PNAS October 29, 2019 116 (44) 22052-22057; first published October 16, 2019. https://doi.org/10.1073/pnas.1908086116
Environmental Sciences
- Open Access
  The concurrent decline of soil lead and children’s blood lead in New Orleans
  Howard W. Mielke, Christopher R. Gonzales, Eric T. Powell, Mark A. S. Laidlaw, Kenneth J. Berry, Paul W. Mielke Jr., and Sara Perl Egendorf
  
  PNAS October 29, 2019 116 (44) 22058-22064; first published October 14, 2019. https://doi.org/10.1073/pnas.1906092116
Physics
- You have access
  Rotation and propulsion in 3D active chiral droplets
  Livio Nicola Carenza, Giuseppe Gonnella, Davide Marenduzzo, and Giuseppe Negro
  
  PNAS October 29, 2019 116 (44) 22065-22070; first published October 14, 2019. https://doi.org/10.1073/pnas.1910909116
- You have access
  Efficient team structures in an open-ended cooperative creativity experiment
  Bernardo Monechi, Giulia Pullano, and Vittorio Loreto
  
  PNAS October 29, 2019 116 (44) 22088-22093; first published October 14, 2019. https://doi.org/10.1073/pnas.1909827116
Statistics
- You have access
  Definitions, methods, and applications in interpretable machine learning
  W. James Murdoch, Chandan Singh, Karl Kumbier, Reza Abbasi-Asl, and Bin Yu
  
  PNAS October 29, 2019 116 (44) 22071-22080; first published October 16, 2019. https://doi.org/10.1073/pnas.1900654116

Biological Sciences

Anthropology
- Open Access
  11,500 y of human–clam relationships provide long-term context for intertidal management in the Salish Sea, British Columbia
  Ginevra Toniello, Dana Lepofsky, Gavia Lertzman-Lepofsky, Anne K. Salomon, and Kirsten Rowell
  
  PNAS October 29, 2019 116 (44) 22106-22114; first published October 14, 2019. https://doi.org/10.1073/pnas.1905921116
- Open Access
  Evidence for independent brain and neurocranial reorganization during hominin evolution
  José Luis Alatorre Warren, Marcia S. Ponce de León, William D. Hopkins, and Christoph P. E. Zollikofer
  
  PNAS October 29, 2019 116 (44) 22115-22121; first published October 14, 2019. https://doi.org/10.1073/pnas.1905071116
Applied Biological Sciences
- You have access
  KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis
  Dana Rabara, Timothy H. Tran, Srisathiyanarayanan Dharmaiah, Robert M. Stephens, Frank McCormick, Dhirendra K. Simanshu, and Matthew Holderfield
  
  PNAS October 29, 2019 116 (44) 22122-22131; first published October 14, 2019. https://doi.org/10.1073/pnas.1908353116
- You have access
  Cytosolic delivery of inhibitory antibodies with cationic lipids
  Hejia Henry Wang and Andrew Tsourkas
  
  PNAS October 29, 2019 116 (44) 22132-22139; first published October 14, 2019. https://doi.org/10.1073/pnas.1913973116
Biochemistry
- Open Access
  AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response
  Nidhi Kumari, M. Abul Hassan, Xiangdong Lu, Robert G. Roeder, and Debabrata Biswas
  
  PNAS October 29, 2019 116 (44) 22140-22151; first published October 14, 2019. https://doi.org/10.1073/pnas.1907097116
- You have access
  PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor
  Katharine L. Diehl, Eva J. Ge, Daniel N. Weinberg, Krupa S. Jani, C. David Allis, and Tom W. Muir
  
  PNAS October 29, 2019 116 (44) 22152-22157; first published October 14, 2019. https://doi.org/10.1073/pnas.1911775116
- You have access
  The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase
  Artur A. Serebrenik, Gabriel J. Starrett, Sterre Leenen, Matthew C. Jarvis, Nadine M. Shaban, Daniel J. Salamango, Hilde Nilsen, William L. Brown, and Reuben S. Harris
  
  PNAS October 29, 2019 116 (44) 22158-22163; first published October 14, 2019. https://doi.org/10.1073/pnas.1904024116
- You have access
  A mesophilic cysteine-less split intein for protein trans-splicing applications under oxidizing conditions
  Maniraj Bhagawati, Tobias M. E. Terhorst, Friederike Füsser, Simon Hoffmann, Tim Pasch, Shmuel Pietrokovski, and Henning D. Mootz
  
  PNAS October 29, 2019 116 (44) 22164-22172; first published October 14, 2019. https://doi.org/10.1073/pnas.1909825116
Biophysics and Computational Biology
- Open Access
  Proteostasis collapse is a driver of cell aging and death
  Mantu Santra, Ken A. Dill, and Adam M. R. de Graff
  
  PNAS October 29, 2019 116 (44) 22173-22178; first published October 16, 2019. https://doi.org/10.1073/pnas.1906592116
- You have access
  Quantitative structural assessment of graded receptor agonism
  Jinsai Shang, Richard Brust, Patrick R. Griffin, Theodore M. Kamenecka, and Douglas J. Kojetin
  
  PNAS October 29, 2019 116 (44) 22179-22188; first published October 14, 2019. https://doi.org/10.1073/pnas.1909016116
Cell Biology
- You have access
  Cell mechanosensing is regulated by substrate strain energy rather than stiffness
  From the Cover
  
  Valeria Panzetta, Sabato Fusco, and Paolo A. Netti
  
  PNAS October 29, 2019 116 (44) 22004-22013; first published September 30, 2019. https://doi.org/10.1073/pnas.1904660116
- Open Access
  Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancer
  Lavanya Moparthi, Giulia Pizzolato, and Stefan Koch
  
  PNAS October 29, 2019 116 (44) 22189-22195; first published October 14, 2019. https://doi.org/10.1073/pnas.1906484116
- You have access
  Optimized filopodia formation requires myosin tail domain cooperation
  Ashley L. Arthur, Livia D. Songster, Helena Sirkia, Akash Bhattacharya, Carlos Kikuti, Fernanda Pires Borrega, Anne Houdusse, and Margaret A. Titus
  
  PNAS October 29, 2019 116 (44) 22196-22204; first published October 14, 2019. https://doi.org/10.1073/pnas.1901527116
Developmental Biology
- You have access
  Cellular defects resulting from disease-related myosin II mutations in Drosophila
  Karen E. Kasza, Sara Supriyatno, and Jennifer A. Zallen
  
  PNAS October 29, 2019 116 (44) 22205-22211; first published October 15, 2019. https://doi.org/10.1073/pnas.1909227116
Ecology
- You have access
  Amazon deforestation drives malaria transmission, and malaria burden reduces forest clearing
  From the Cover
  
  Andrew J. MacDonald and Erin A. Mordecai
  
  PNAS October 29, 2019 116 (44) 22212-22218; first published October 14, 2019. https://doi.org/10.1073/pnas.1905315116
Evolution
- You have access
  Middle Paleolithic complex technology and a Neandertal tar-backed tool from the Dutch North Sea
  From the Cover
  
  Marcel J. L. Th. Niekus, Paul R. B. Kozowyk, Geeske H. J. Langejans, Dominique Ngan-Tillard, Henk van Keulen, Johannes van der Plicht, Kim M. Cohen, Willy van Wingerden, Bertil van Os, Bjørn I. Smit, Luc W. S. W. Amkreutz, Lykke Johansen, Annemieke Verbaas, and Gerrit L. Dusseldorp
  
  PNAS October 29, 2019 116 (44) 22081-22087; first published October 21, 2019. https://doi.org/10.1073/pnas.1907828116
- You have access
  Multilayered horizontal operon transfers from bacteria reconstruct a thiamine salvage pathway in yeasts
  Carla Gonçalves and Paula Gonçalves
  
  PNAS October 29, 2019 116 (44) 22219-22228; first published October 14, 2019. https://doi.org/10.1073/pnas.1909844116
Genetics
- You have access
  Tissue-specific FAH deficiency alters sleep–wake patterns and results in chronic tyrosinemia in mice
  Shuzhang Yang, Sandra M. Siepka, Kimberly H. Cox, Vivek Kumar, Marleen de Groot, Yogarany Chelliah, Jun Chen, Benjamin Tu, and Joseph S. Takahashi
  
  PNAS October 29, 2019 116 (44) 22229-22236; first published October 14, 2019. https://doi.org/10.1073/pnas.1904485116
- You have access
  Gastrointestinal dysfunction in autism displayed by altered motility and achalasia in Foxp1^+/− mice
  Henning Fröhlich, Marie Luise Kollmeyer, Valerie Catherine Linz, Manuel Stuhlinger, Dieter Groneberg, Amelie Reigl, Eugen Zizer, Andreas Friebe, Beate Niesler, and Gudrun Rappold
  
  PNAS October 29, 2019 116 (44) 22237-22245; first published October 14, 2019. https://doi.org/10.1073/pnas.1911429116
Immunology and Inflammation
- You have access
  4D electron microscopy of T cell activation
  Yue Lu, Byung-Kuk Yoo, Alphonsus H. C. Ng, Jungwoo Kim, Sinchul Yeom, Jau Tang, Milo M. Lin, Ahmed H. Zewail, and James R. Heath
  
  PNAS October 29, 2019 116 (44) 22014-22019; first published October 14, 2019. https://doi.org/10.1073/pnas.1914078116
- You have access
  Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities
  Salahaldin A. Tahir, Jianjun Gao, Yuji Miura, Jorge Blando, Rebecca S. S. Tidwell, Hao Zhao, Sumit K. Subudhi, Hussein Tawbi, Emily Keung, Jennifer Wargo, James P. Allison, and Padmanee Sharma
  
  PNAS October 29, 2019 116 (44) 22246-22251; first published October 14, 2019. https://doi.org/10.1073/pnas.1908079116
- Open Access
  Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules
  From the Cover
  
  S. Harsha Krovi, John W. Kappler, Philippa Marrack, and Laurent Gapin
  
  PNAS October 29, 2019 116 (44) 22252-22261; first published September 30, 2019. https://doi.org/10.1073/pnas.1909504116
- You have access
  Myeloid cells activate iNKT cells to produce IL-4 in the thymic medulla
  Haiguang Wang, Elise R. Breed, You Jeong Lee, Lily J. Qian, Stephen C. Jameson, and Kristin A. Hogquist
  
  PNAS October 29, 2019 116 (44) 22262-22268; first published October 14, 2019. https://doi.org/10.1073/pnas.1910412116
Medical Sciences
- You have access
  Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis
  Alexia Belavgeni, Stefan R. Bornstein, Anne von Mässenhausen, Wulf Tonnus, Julian Stumpf, Claudia Meyer, Evelyn Othmar, Markus Latk, Waldemar Kanczkowski, Matthias Kroiss, Constanze Hantel, Christian Hugo, Martin Fassnacht, Christian G. Ziegler, Andrew V. Schally, Nils P. Krone, and Andreas Linkermann
  
  PNAS October 29, 2019 116 (44) 22269-22274; first published October 14, 2019. https://doi.org/10.1073/pnas.1912700116
- Open Access
  Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate
  Yehuda Halfon, Alicia Jimenez-Fernandez, Ruggero La Rosa, Rocio Espinosa Portero, Helle Krogh Johansen, Donna Matzov, Zohar Eyal, Anat Bashan, Ella Zimmerman, Matthew Belousoff, Søren Molin, and Ada Yonath
  
  PNAS October 29, 2019 116 (44) 22275-22281; first published October 14, 2019. https://doi.org/10.1073/pnas.1909831116
- You have access
  CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation
  Ali Reza Saadatmand, Viviana Sramek, Silvio Weber, Daniel Finke, Matthias Dewenter, Carsten Sticht, Norbert Gretz, Till Wüstemann, Marco Hagenmueller, Stephan R. Kuenzel, Stefanie Meyer-Roxlau, Martin Kramer, Samuel Sossalla, Lorenz H. Lehmann, Susanne Kämmerer, Johannes Backs, and Ali El-Armouche
  
  PNAS October 29, 2019 116 (44) 22282-22287; first published October 16, 2019. https://doi.org/10.1073/pnas.1816521116
- Open Access
  Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy
  Boris Klimovich, Samet Mutlu, Jean Schneikert, Sabrina Elmshäuser, Maria Klimovich, Andrea Nist, Marco Mernberger, Oleg Timofeev, and Thorsten Stiewe
  
  PNAS October 29, 2019 116 (44) 22288-22293; first published October 14, 2019. https://doi.org/10.1073/pnas.1910255116
- Open Access
  Alternative pathway androgen biosynthesis and human fetal female virilization
  Nicole Reisch, Angela E. Taylor, Edson F. Nogueira, Daniel J. Asby, Vivek Dhir, Andrew Berry, Nils Krone, Richard J. Auchus, Cedric H. L. Shackleton, Neil A. Hanley, and Wiebke Arlt
  
  PNAS October 29, 2019 116 (44) 22294-22299; first published October 14, 2019. https://doi.org/10.1073/pnas.1906623116
- Open Access
  Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes
  Sara Lázaro, Miriam Pérez-Crespo, Corina Lorz, Alejandra Bernardini, Marta Oteo, Ana Belén Enguita, Eduardo Romero, Pilar Hernández, Laura Tomás, Miguel Ángel Morcillo, Jesús M. Paramio, and Mirentxu Santos
  
  PNAS October 29, 2019 116 (44) 22300-22306; first published October 14, 2019. https://doi.org/10.1073/pnas.1821745116
Microbiology
- You have access
  Aggregatibacter actinomycetemcomitans colonization and persistence in a primate model
  Senthil Kumar Velusamy, Vandana Sampathkumar, Narayanan Ramasubbu, Bruce J. Paster, and Daniel H. Fine
  
  PNAS October 29, 2019 116 (44) 22307-22313; first published October 14, 2019. https://doi.org/10.1073/pnas.1905238116
- You have access
  A Wolbachia nuclease and its binding partner provide a distinct mechanism for cytoplasmic incompatibility
  Hongli Chen, Judith A. Ronau, John F. Beckmann, and Mark Hochstrasser
  
  PNAS October 29, 2019 116 (44) 22314-22321; first published October 15, 2019. https://doi.org/10.1073/pnas.1914571116
- Open Access
  Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection
  James D. Nhan, Christian D. Turner, Sarah M. Anderson, Chia-An Yen, Hans M. Dalton, Hilary K. Cheesman, Dana L. Ruter, Nandhitha Uma Naresh, Cole M. Haynes, Alexander A. Soukas, Read Pukkila-Worley, and Sean P. Curran
  
  PNAS October 29, 2019 116 (44) 22322-22330; first published October 14, 2019. https://doi.org/10.1073/pnas.1909666116
- Open Access
  Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals
  Chao Wang, Fuzhou Ye, Changqing Chang, Xiaoling Liu, Jianhe Wang, Jinpei Wang, Xin-Fu Yan, Qinqin Fu, Jianuan Zhou, Shaohua Chen, Yong-Gui Gao, and Lian-Hui Zhang
  
  PNAS October 29, 2019 116 (44) 22331-22340; first published October 11, 2019. https://doi.org/10.1073/pnas.1903695116
Neuroscience
- You have access
  Population-based neuroimaging reveals traces of childbirth in the maternal brain
  Ann-Marie G. de Lange, Tobias Kaufmann, Dennis van der Meer, Luigi A. Maglanoc, Dag Alnæs, Torgeir Moberget, Gwenaëlle Douaud, Ole A. Andreassen, and Lars T. Westlye
  
  PNAS October 29, 2019 116 (44) 22341-22346; first published October 15, 2019. https://doi.org/10.1073/pnas.1910666116
- Open Access
  Myelin sheath structure and regeneration in peripheral nerve injury repair
  Bin Liu, Wang Xin, Jian-Rong Tan, Rui-Ping Zhu, Ting Li, Dan Wang, Sha-Sha Kan, Ding-Kui Xiong, Huan-Huan Li, Meng-Meng Zhang, Huan-Huan Sun, William Wagstaff, Chan Zhou, Zhi-Jian Wang, Yao-Guang Zhang, and Tong-Chuan He
  
  PNAS October 29, 2019 116 (44) 22347-22352; first published October 14, 2019. https://doi.org/10.1073/pnas.1910292116
Pharmacology
- You have access
  Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes
  From the Cover
  
  Aritro Nath, Eunice Y. T. Lau, Adam M. Lee, Paul Geeleher, William C. S. Cho, and R. Stephanie Huang
  
  PNAS October 29, 2019 116 (44) 22020-22029; first published September 23, 2019. https://doi.org/10.1073/pnas.1909998116
- Open Access
  A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor
  Zoltan Dekan, Setareh Sianati, Arsalan Yousuf, Katy J. Sutcliffe, Alexander Gillis, Christophe Mallet, Paramjit Singh, Aihua H. Jin, Anna M. Wang, Sarasa A. Mohammadi, Michael Stewart, Ranjala Ratnayake, Frank Fontaine, Ernest Lacey, Andrew M. Piggott, Yan P. Du, Meritxell Canals, Richard B. Sessions, Eamonn Kelly, Robert J. Capon, Paul F. Alewood, and MacDonald J. Christie
  
  PNAS October 29, 2019 116 (44) 22353-22358; first published October 14, 2019. https://doi.org/10.1073/pnas.1908662116
Physiology
- Open Access
  Mother-to-embryo vitellogenin transport in a viviparous teleost Xenotoca eiseni
  Atsuo Iida, Hiroyuki N. Arai, Yumiko Someya, Mayu Inokuchi, Takeshi A. Onuma, Hayato Yokoi, Tohru Suzuki, Eiichi Hondo, and Kaori Sano
  
  PNAS October 29, 2019 116 (44) 22359-22365; first published October 8, 2019. https://doi.org/10.1073/pnas.1913012116
Plant Biology
- Open Access
  Fundamental helical geometry consolidates the plant photosynthetic membrane
  Yuval Bussi, Eyal Shimoni, Allon Weiner, Ruti Kapon, Dana Charuvi, Reinat Nevo, Efi Efrati, and Ziv Reich
  
  PNAS October 29, 2019 116 (44) 22366-22375; first published October 14, 2019. https://doi.org/10.1073/pnas.1905994116
- Open Access
  Highly ABA-Induced 1 (HAI1)-Interacting protein HIN1 and drought acclimation-enhanced splicing efficiency at intron retention sites
  Geeng Loo Chong, Mung Hsia Foo, Wen-Dar Lin, Min May Wong, and Paul E. Verslues
  
  PNAS October 29, 2019 116 (44) 22376-22385; first published October 14, 2019. https://doi.org/10.1073/pnas.1906244116
Population Biology
- Open Access
  The contribution of host cell-directed vs. parasite-directed immunity to the disease and dynamics of malaria infections
  Nina Wale, Matthew J. Jones, Derek G. Sim, Andrew F. Read, and Aaron A. King
  
  PNAS October 29, 2019 116 (44) 22386-22392; first published October 15, 2019. https://doi.org/10.1073/pnas.1908147116
Sustainability Science
- You have access
  TROPOMI reveals dry-season increase of solar-induced chlorophyll fluorescence in the Amazon forest
  Russell Doughty, Philipp Köhler, Christian Frankenberg, Troy S. Magney, Xiangming Xiao, Yuanwei Qin, Xiaocui Wu, and Berrien Moore III
  
  PNAS October 29, 2019 116 (44) 22393-22398; first published October 14, 2019. https://doi.org/10.1073/pnas.1908157116
Systems Biology
- Open Access
  Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling
  Peter Kreuzaler, Matthew A. Clarke, Elizabeth J. Brown, Catherine H. Wilson, Roderik M. Kortlever, Nir Piterman, Trevor Littlewood, Gerard I. Evan, and Jasmin Fisher
  
  PNAS October 29, 2019 116 (44) 22399-22408; first published October 14, 2019. https://doi.org/10.1073/pnas.1903485116

Correction

You have access
Correction for Sah et al., Future epidemiological and economic impacts of universal influenza vaccines
PNAS October 29, 2019 116 (44) 22409; first published October 21, 2019. https://doi.org/10.1073/pnas.1917260116

SI Correction

You have access
Correction to Supporting Information for Pearce et al., Variation in the β-endorphin, oxytocin, and dopamine receptor genes is associated with different dimensions of human sociality
PNAS October 29, 2019 116 (44) 22410; first published October 21, 2019. https://doi.org/10.1073/pnas.1917121116

This page is brought to you by Brian Golding (Golding@McMaster.CA) and is copied locally here to speed your access. To go to the original page (should you find something interesting or should you wish to follow links) click on Current Issue of PNAS

Main menu

User menu

Search

New Research In

Physical Sciences

Featured Portals

Articles by Topic

Social Sciences

Featured Portals

Articles by Topic

Biological Sciences

Featured Portals

Articles by Topic

Table of Contents

This Week in PNAS

Science and Culture

Core Concepts

Commentaries

Letters

Brief Report

Physical Sciences

Applied Mathematics

Applied Physical Sciences

Biophysics and Computational Biology

Chemistry

Earth, Atmospheric, and Planetary Sciences

Environmental Sciences

Physics

Statistics

Social Sciences

Anthropology

Psychological and Cognitive Sciences

Social Sciences

Sustainability Science

Biological Sciences

Anthropology

Applied Biological Sciences

Biochemistry

Biophysics and Computational Biology

Cell Biology

Developmental Biology

Ecology

Evolution

Genetics

Immunology and Inflammation

Medical Sciences

Microbiology

Neuroscience

Pharmacology

Physiology

Plant Biology

Population Biology

Sustainability Science

Systems Biology

Correction

SI Correction

In this issue

Jump to

Articles

PNAS Portals

Information

This page is brought to you by Brian Golding (Golding@McMaster.CA) and is copied locally here to speed your access. To go to the original page (should you find something interesting or should you wish to follow links) click on

Current Issue of PNAS