Dear Colleagues, We are inviting abstract submissions for our symposium, "Novel Insights on Genome Architecture Evolution" (Symposium #8) at the 2025 Annual Meeting of the Society for Molecular Biology & Evolution, July 20-24 in Beijing China. Details are below: SMBE 2025 - Annual Meeting of the Society for Molecular Biology & Evolution, 2025 smbe2025.scimeeting.cn Novel Insights on Genome Architecture Evolution Organizers: Carol Eunmi LEE, University of Wisconsin-Madison, USA Sean Chun-Chang CHEN, Taipei Medical University Invited Speaker: Chris Jiggins, University of Cambridge The rapid expansion of genomic data is revolutionizing our ability to make unprecedented discoveries regarding patterns, mechanisms, and consequences of genome architecture evolution. With comprehensive genome sequencing across diverse taxa, we can now address fundamental questions on how large-scale structural variation in genomes arise and how they might impact adaptive potential and speciation. For instance, we are only beginning to uncover how chromosomal rearrangements, such as fusions, fissions, and inversions, contribute to adaptation and speciation. In addition, we are gaining new insights into how allopolyploid hybridization in plants results in novel genome architectures and potentially leads to highly invasive species. Moreover, we can now explore how genome architecture evolution leads to morphological and functional innovations, such as the evolution of animal body plans. Thus, this symposium will assemble researchers who investigate the dynamics of genome architecture evolution in multicellular organisms. We especially welcome talks that focus on large scale genomic comparisons that delve into mechanisms underlying genome structural variation and evolution and impacts of that variation on responses to selection or the evolution of novelty. Conceptual and theoretical talks that provide novel perspectives are also welcome. As such, this symposium aims to highlight the importance of genome architecture in shaping evolutionary trajectories and adaptive potential. Carol Eunmi LEE (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)