Dear Colleagues: I encourage you to submit abstracts for oral and poster presentations at SMBE 2026 on artificial intelligence (AI) and machine learning (ML) in molecular evolution and phylogenetics. The symposium title is "Powers and pitfalls of artificial intelligence for molecular evolution and phylogenetics." You can find its description at https://smbe2026.org/programme Abstract submission deadline: February 3, 2026 (please specify symposium #S02). Invited Speakers are: Anne-Florence Bitbol - EFPL (�cole Polytechnique F�d�rale de Lausanne), Switzerland Sudhir Kumar - Institute for Genomics and Evolutionary Medicine, Temple University, USA Symposium description Artificial intelligence (AI) is poised to reshape the landscape of molecular evolution and phylogenetics. A growing number of machine learning and deep learning methods are being developed for tasks ranging from inferring evolutionary trees and detecting selection to modeling sequence evolution and predicting protein structures. Yet many remain skeptical, as fundamental questions persist: What exactly do these models learn from biological data? How do their internal representations relate to established evolutionary principles? And crucially, what are their blind spots? This symposium at the SMBE annual meetings in Copenhagen (Jun 28-Jul 02, 2026) will provide a timely forum for examining both the transformative potential and the critical limitations of AI and ML in evolutionary research. Speakers will explore how AI models capture patterns of evolutionary variation and divergence, and whether their learned representations and models genuinely reflect underlying evolutionary mechanisms. The session will also feature discussions of new methodological advances, emerging interpretability frameworks, and benchmark analyses testing the reliability and reproducibility of AI-driven inferences. Sudhir Kumar (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)