Dear colleagues, We are excited to announce a symposium on EVOLUTION AND BIOLOGICAL NOISE at the 3rd Joint Congress on Evolutionary Biology in Montr�al, July 26 - 30, 2024. INTELLECTUAL MOTIVATION: Phenotypic variation is the substrate of evolution by natural selection. One source of phenotypic variation is biological noise, which can be generated both during reproduction (e.g. mutations) and development (e.g. mistranscription, mistranslation). Critically, the amount of phenotypic variation resulting from biological noise can be under heritable, genetic control. For example, DNA polymerase, RNA-polymerases and ribosomal protein alleles can differ in their accuracy of replication, transcription, and translation, respectively. This fact raises the possibility that the amount of biological noise, and hence, the amount of phenotypic variability in an evolving population may itself be subject to natural selection. TIMELINESS: Interest in the evolution of biological noise goes back at least 80 years, but stimulated by rapid technological advances (e.g., single-cell phenotypic and genetic characterization), the past 20 years have seen an explosion of work. Today, biological noise is under active investigation in diverse intellectual communities including molecular modelling, gene expression and functional biology, developmental biology, transmission genetics, biophysics, systems and synthetic biology, and population genetics. There is also a growing appreciation of the role of biological noise in human health. OBJECTIVES: The purpose of this symposium is to draw workers together from across communities in order to develop a greater understanding of the empirical and conceptual similarities and differences among these many domains of inquiry into the evolution of biological noise. The organizers are especially interested in developing a deeper qualitative and quantitative understanding of the selective tension between the deleterious and beneficial consequences of biological noise. Questions? Contact the symposium organizers Nacho Bravo ( ignacio.bravo@cnrs.fr) or Dan Weinreich (daniel_weinreich@brown.edu). Important dates: * Registration is now open. * Early-bird registration rates available until May 1. * Talk submissions due by May 1. * Conference dates: July 26 - 30. (Also perhaps of interest: the Montreal Jazz Festival opens July 27...) This is the link to the instructions for registering and submitting an abstract, and then choosing the symposium of your interest: https://www.evolutionmeetings.org/registration.html Please note there is no risk in applying to symposia--talks not selected for symposia will be scheduled in concurrent sessions. https://www.evolutionmeetings.org/instructions-for-presenters.html Please join us in making some (biological) noise this summer in Montr�al! daniel_weinreich@brown.edu (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)