Dear evoldir community, We would like to attract your attention to the following symposium at the Evolution 2024 conference in Montr�al. Title: From mutation rate to mutations rates: how uncovering the mutation rates variations change our understanding of adaptation Description: Mutations are the raw material on which selection acts and the origin of biodiversity. Until recently, much of the research on the contribution of mutations to adaptation has been focused on genome wide base substitution rate (�bs) and the evolutionary forces shaping it. Now, the easier and cheaper access to whole genome sequences and the improvement of genomic analyses allows to better document the variation of the mutation rate across the tree of life, but also to measure the rate of other mutation types, in particular structural mutations. Recent researches have also unraveled variations of mutation rates and spectrum with environmental factors and genomic context, sometimes of greater amplitude than the variation in mutation rate observed between closely related species. The picture of the evolution of mutation rates and the contribution of mutation rates to adaptation is thus becoming more colourful and more complex. In this symposium, we hope to bring together theoretical, genomic and experimental approaches to integrate the different facets of mutation rate and of its contribution to determining the adaptive paths taken. Organizers: Marc Krasovec (marc.krasovec@obs-banyuls.fr) St�phanie Bedhomme (stephanie.bedhomme@cefe.cnrs.fr) We hope to see you in Montr�al! Stephanie BEDHOMME (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)