Dear all, Please find below an advertisement and invitation to attend the 3rd edition of the colloquium "*Expanding evolutionary theories of ageing to take into account symbioses and interactions throughout the Web of Life*". Feel very free to advertise by forwarding this email to anyone you may think would be interested. The event is free, hybrid (attendees can join either in person or virtually) but upon registration by email before September 14th to : epbapteste@gmail.com. When emailing, please let me know whether you would prefer to attend virtually or in person (40 seats, on a first serve, first come basis). It will take place within the University Jussieu, Jussieu Campus, on October 14th, 2024. Kind regards, Eric Bapteste Program: This colloquium will seek to explore traditional limits to the main evolutionary theories of ageing and to propose novel findings to improve our understanding of how, why and when organisms age in the Web of Life. It will question the explanatory scope and the phylogenetic scope of at least three leading, stimulating evolutionary theories of ageing, namely the Mutation Accumulation theory, the Antagonistic pleiotropy theory and the Disposable Soma theory. Indeed, these theories share a common blindspot. The first two have been developed under the traditional framework of population genetics, and therefore are logically centered on the ageing of individuals within a population or within a species. The third one is usually applied to explain ageing within a species. Consequently, these theories do not explicitly model the countless interspecific and ecological interactions, such as symbioses and host-microbiomes associations, however well-known to affect many organismal traits as well as organismal evolution. Moreover, these theories have been mostly developed with animal models in mind, mainly those with a neat germen/soma distinction, such as mice and humans, and for this reason all these theories may benefit from novel conceptual developments to further justify and possibly expand their application scope towards other taxa, such as unicellular organisms (protists, bacteria and archaea), which have long been considered, by default and probably erroneously, as non-senescent, and such as extremely long lived taxa, which owing to their unusual biology may still have some lessons to contribute to these theories. *Scientific program for the day:* *Provisional program (the speaker order is not truly in order yet)* *The current theoretical framework and some of its limits* *Pr. Suresh Rattan* (Department of Molecular Biology and Genetics, Aarhus University, DENMARK) « *Deepest open issues in the theories of ageing and its evolution*» *Pr. Annette Baudisch* (University of Southern Denmark, DK) « *Why do we need inclusive definitions of ageing?*» *Microbiome and Ageing * *Pr. Paul O'Toole *(School of Microbiology & APC Microbiome Institute Room 447 Food Science Building, University College Cork, T12 Y337 Cork, Ireland.) « *Contribution of the gut microbiome to human ageing at different ages* » *Pr. Dario Valenzano* (Leibniz Institute on Ageing, Beutenbergstraße 11 07745 Jena, Germany) « *Evolution of the microbiome during host ageing and rejuvenation*» *Alternative models to study ageing* *Pr. Ulrich Karl Steiner *(Institute of Biology, FU-Berlin, Germany) « *Latest discoveries about bacterial ageing.* » *Dr. Mart Krupovic *(Pasteur Institute, Paris, France) « *First evidence of ageing in Archaea.* » *Pr. Emma Teeling* (University College Dublin, Ireland) « *New lessons about ageing from non-model organisms* » *Dr. Jean-François Le Galliard* (CNRS - UMS 3194, CEREEP-Ecotron IleDeFrance, Département de biologie, Ecole Normale Supérieure - PSL Research University, St-Pierre-lès-Nemours, France) "*Ecology and ageing: lizard senescence as a case study*" *Organisational complexity and ageing* *Mr. Thomas Duffield* (Institute of Inflammation and Ageing ; University of Birmingham ; Queen Elizabeth Hospital ; Mindelsohn Way Birmingham, B15 2WB United Kingdom) « *Epigenetics failure and ageing *» *Pr. Claudio Franceschi* (U. Bologna, Italy) "*Heterogeneity in individual ageing*" *Dr. Eric Chenin *(IRD / UMMISCO, MNHN / GBIF France) "*Three stages of* *system aging: malleability, elasticity and rigidity*" *Evolution of ageing and ageing related diseases * *Dr. Samuel Pavard* (MNHN, Paris, France) « *Joint evolution of cancer and ageing related diseases in mammals *» *Mr. Hugo Bonnefous* (SU, ISYEB, Paris, France) « *Evolutionary history of Ageing-Related Disease genes* ». *Conclusion* *Dr. Jessica Lombard *(ETHICS - EA 7446, Université Catholique de Lille) « *Transhumanist movements and Evolutionary theories of aging: Uses and Misuses *» *Dr. Maël Lemoine *(Université de Bordeaux, France) « *What are the deepest philosophical issues about ageing and its evolution?*» Dr. Eric Bapteste 7, quai Saint-Bernard, Université Pierre et Marie Curie, UMR 7205 ISYEB, Bâtiment A, 4eme et. pièce 427, Paris 75005 France - Livre pour enfants et curieux: "Le monde surprenant des microbes: virus, bactéries, archées,..." (Editions Circonflexe) "Tout se transforme! Comment marche l'évolution" (Editions Circonflexe) Livres pour adultes: "Tous entrelacés! Des gènes aux super-organismes, les réseaux de l'évolution" (Belin) "Les gènes voyageurs: l'odyssée de l'évolution" (Belin) "Conflits intérieurs: fable scientifique" (Editions Matériologiques) Bapteste Eric (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)