PhD Position: Uncovering evolutionary history and interactive of centriolar proteins CO-SUPERVISION Laboratory of Computational Biology and Theoretical Biophysics, Prof. Bitbol Laboratory of Cell and Developmental Biology, Prof. G�nczy PROJECT DESCRIPTION Centrioles are ancient eukaryotic organelles critical for cell division, motility and signaling. In this joint project between the groups of Prof. Bitbol and Prof. G�nczy, the evolutionary history of centriolar proteins will be uncovered using novel structure-aware phylogeny inference algorithms. Moreover, protein and proteome language models will be developed and deployed to infer the interactome of centriolar proteins, and investigate its evolution. Furthermore, building blocks of the centriole will be sought outside eukaryotes, thereby potentially uncovering the evolutionary origin of this critical organelle. REQUIREMENTS - Master's degree in computational biology, evolutionary biology, or related field (by start date) - Interest in understanding mechanisms of organelle evolution and molecular phylogenetics - Strong programming skills - Good English communication skills WE OFFER - A fully funded PhD position with competitive Swiss salary - A collaborative research environment START DATE - June 2026 (or thereafter, upon mutual arrangement) APPLICATIONS Submit your application through the Computational and Quantitative Biology (EDCB) EPFL doctoral program -deadline April 15, 2026 (https://www.epfl.ch/education/phd/edcb-computational-and-quantitative-biology/edcb-how-to-apply/) Further information can be obtained from Anne-Florence Bitbol (anne-florence.bitbol@epfl.ch) or Pierre G�nczy (pierre.gonczy@epfl.ch) Pierre G�nczy (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)