PhD Position available (65% E13 TV-L) University of Mainz, Institute of Organismic and Molecular Evolution Supervisor: Prof Dr Meret Huber (https://plant-evolutionary-ecology.uni-mainz.de/) Starting date: January 2025 or to be agreed upon The role of small RNAs in transgenerational plasticity in plants Background & project goal: Organisms may modulate their phenotype across generations in the absence of genetic change. Yet, the underlying molecular mechanisms of such transgenerational plasticity are little understood. In plants, small RNAs are hypothesized to mediate transgenerational plasticity. However, this hypothesis and its evolutionary consequences still need to be tested. In this project, we will assess the role of small RNAs in transgenerational plasticity of the giant duckweed (Spirodela polyrhiza) under attack of one of its major native herbivores, the waterlily aphid (Rhopalosiphum nymphaeae). We will address the following key questions: i) Does aphid herbivory remodel small RNAs in the duckweed? ii) Are changes in small RNAs associated with gene expression and defenses?, and iii) Are these small RNAs transmitted across generations and thereby modulate offspring gene expression and fitness? We look for an enthusiastic and ambitious PhD student with strong interest in plant-herbivore interactions, epigenetic inheritance and evolution. As this PhD project is highly interdisciplinary, spanning genetic engineering through CRISPR, experimental evolution and high-throughput sequencing, the PhD student should have a solid background in one of these methodologies and eagerness to embrace the other approaches. Previous experience in plant research is advantageous but not required. The applicant must be fluent in English and hold a MSc degree in Biology or related fields. We offer a stimulating and interdisciplinary research environment including state-of-the-art facilities in a dynamic and international research environment. The successful applicant can join the graduate school GenEvo ("Gene Regulation in Evolution"; https://www.genevo-rtg.de/), and fully benefit from its tailored programme. How to apply: Please send a single pdf including i) a motivation letter (max. 2 pages), ii) detailed CV, iii) copies of BSc and MSc degree, and iv) names and addresses of two referees to meret.huber@uni-mainz.de. The screening process will start immediately and continue until the position is filled. Prof. Dr. Meret Huber Plant Evolutionary Ecology Institute of Organismic and Molecular Evolution University ofMainz Johann-Joachim-Becher-Weg 7 55128 Mainz Germany Phone: 0049 (0)6131 39 302 60 meret.huber@uni-mainz.de https://plant-evolutionary-ecology.uni-mainz.de/ "Huber, Prof. Meret" (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)