Postdoc in Mating and Gene flow in Candida albicans

The Ono lab in the School of Life Sciences at the University of Nottingham
is seeking a postdoctoral research associate to join a project on
gene flow in pathogenic fungi. The postdoctoral associate will conduct
research to investigate mating and gene flow of the opportunistic pathogen
Candida albicans.

This post is part of a collaborative multi-national Wellcome Trust award
involving academic collaborative partners in the UK and South Africa
with the aim of understanding the biology of adaptation in fungal
pathogens. The post will use a combination of classical, genomic,
molecular and bioinformatic techniques to investigate mating and its
consequences between strains of Candida albicans, a common cause of fungal
infections in humans. Specific aims are to investigate the ability of
strains from different clades to mate, examine whether there are any
post-mating barriers between clades, and determine the consequences of
gene flow for temperature adaptation. The post holder will be expected
to undertake independent research as well as work as part of a team. This
will include using approaches or methodologies and techniques appropriate
to the type of research, and they will be responsible for writing up
their work to contribute to published outcomes.

The role holder will have the opportunity to use their initiative and
creativity to identify areas for research, develop research methods and
extend their research portfolio.

Candidates must hold a PhD, or be near to submission of a PhD, in a
relevant field of Microbiology or Evolutionary Genetics, ideally involving
Fungal Biology. They must understand microbial laboratory practices and
have existing skills in microbial culture. They must be familiar with
molecular biology techniques (e.g. DNA extraction, electrophoresis and
PCR) including transformation and possess genomic and statistical analysis
skills. Previous experience of working with microbes is essential, with
experience of yeast, and especially Candida species, highly desirable.

To apply for the post please visit
https://jobs.nottingham.ac.uk/Vacancy.aspx?id=53421&forced=2 The closing
date for applications is 1 December, 2025.

Informal enquiries may be addressed to Jasmine Ono at
jasmine.ono@nottingham.ac.uk. Please note that applications sent directly
to this e-mail address will not be accepted.

The School of Life Sciences holds an Athena Swan Gold Award, in
recognition of our commitment to supporting and advancing equality and
inclusion in the Life Sciences.

Jasmine Ono
Pronouns: she/her
BBSRC Discovery Fellow
Assistant Professor in Evolutionary Functional Genomics
University of Nottingham

"Jasmine Ono (staff)" <Jasmine.Ono@nottingham.ac.uk>

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