Dear all, Registration is now open for the Physalia online course Comparative Genomics (6th edition), taking place 23-27 February 2026. Course website: ( https://www.physalia-courses.org/courses-workshops/course34/ ) Across five days, participants will learn key concepts and gain hands-on experience with state-of-the-art tools for: de novo genome assembly and annotation identification of SNPs and SVs evaluation of sequencing technologies (Illumina, PacBio, ONT) comparative analyses across multiple genomes functional interpretation of genomic variation in an evolutionary context Each day includes a lecture and group discussion of core principles, followed by guided practical exercises. Participants will work through mirroring tasks with the instructors and complete individual analyses on provided datasets, with opportunities to bring and discuss their own data. Program Overview: Mon: Introduction; file formats; assembly concepts; QC and initial assembly Tue: Full de novo assembly (short + long reads); assembly metrics Wed: Genome annotation; repeats; gene prediction; synteny; Maker2 and IGV Thu: Structural variant biology; mapping strategies; SV calling and comparison Fri: Functional impact of variants; GO, KEGG, orthology; summary discussion For full list of our courses and workshops, please visit: ( https://www.physalia-courses.org/courses-workshops/ ) Best regards, Carlo Carlo Pecoraro, Ph.D Physalia-courses DIRECTOR info@physalia-courses.org mobile: +49 17645230846 ( https://www.linkedin.com/in/physalia-courses-a64418127/ ) "info@physalia-courses.org" (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)