Dear colleagues, We are excited to announce the second edition of the course "Proteomic methods for species identification of archaeological and palaeontological materials." Dates and schedule: Online live sessions on December 12th, 16th, 18th, 2024. From 14:00 to 18:00 (Madrid time zone). Instructor: Dr. Michael Buckley [1] (University of Manchester, UK). This course addresses archaeologists and palaeontologists willing to learn how to identify species from proteomic information. Programme: * Introduction to ancient proteins and reasons for analysing them and the most appropriate biochemical methods to do so, relating to sample type * Short introduction on protein structure, evolution, and ongoing investigations in zooarchaeology and palaeobiology * Learn the basics of proteomics * Introduction to the differences between ionization techniques, mass analysers, and fragmentation methods. * Illustration with worked examples of _de novo_ sequencing peptides and probability-based sequence matching. * Identifying a species from a peptide mass fingerprint * Introduction on how to identify ancient collagen fingerprints and understand the confidence levels for taxonomic assignment * Learn the use of automated tools for identification that include machine learning, and understand their limitations * Learn to infer a species through the proteome analysis of an ancient sample * Learn how to interpret sequence data from complex samples of unknown species * Identify confidence levels of cross-species sequence interpretations through protein BLAST and the Ensembl Genome Browser * Summary * Summary of the various techniques' strengths and weaknesses, assumptions for each approach, some standard open-source tools available, and alternative tools currently available on R with some worked examples. More information and registration: https://www.transmittingscience.com/courses/genetics-and-genomics/palaeoproteomics-and-zooarchaeology-by-mass-spectrometry-zooms/ or writing to courses@transmittingscience.com Best wishes Sole Soledad De Esteban-Trivigno, PhD Director Transmitting Science www.transmittingscience.com/courses Twitter @SoleDeEsteban Orcid: https://orcid.org/0000-0002-2049-0890 Under the provisions of current regulations on the protection of personal data, Regulation (EU) 2016/679 of 27 April 2016 (GDPR), we inform you that personal data and email address, collected from the data subject will be used by TRANSMITTING SCIENCE SL to manage communications through email and properly manage the professional relationship with you. The data are obtained based on a contractual relationship or the legitimate interest of the Responsible, likewise the data will be kept as long as there is a mutual interest for it. The data will not be communicated to third parties, except for legal obligations. We inform you that you can request detailed information on the processing as well as exercise your rights of access, rectification, portability and deletion of your data and those of limitation and opposition to its treatment by contacting Calle Gardenia, 2 Urb. Can Claramunt de Piera CP: 08784 (Barcelona) or sending an email to info@transmittingscience.com or http://transmittingscience.com/additional-terms. If you consider that the processing does not comply with current legislation, you can complain with the supervisory authority at www. aepd.es . Confidentiality. - The content of this communication, as well as that of all the attached documentation, is confidential and is addressed to the addressee. If you are not the recipient, we request that you indicate this to us and do not communicate its contents to third parties, proceeding to its destruction. Disclaimer of liability. - The sending of this communication does not imply any obligation on the part of the sender to control the absence of viruses, worms, Trojan horses and/or any other harmful computer program, and it corresponds to the recipient to have the necessary hardware and software tools to guarantee both the security of its information system and the detection and elimination of harmful computer programs. TRANSMITTING SCIENCE SL shall not be liable. Links: [1] https://www.transmittingscience.com/instructors/michael-buckley/ Soledad De Esteban-Trivigno (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)