Second call for applications --- On behalf of the organizing committee, it is my pleasure to announce the workshop "Polygenic adaptation: from quantitative genetics to population genomics", part of the QLife Quantitative Biology Winter School Series. Topic: Adaptation to novel environments depends on many alleles with largely undetectable fitness effects. With the advance of DNA sequencing technologies, the combination of genome-wide association analyses with genomic prediction methods has become the state-of-the-art approach to link adaptive trait responses to genetic changes at the molecular level. The workshop will introduce students to evolutionary theory and the tools employed to test alternative models of polygenic adaptation. Current advances in detecting polygenic adaptation in experimental and natural populations will be discussed. The course will introduce the participants to the analysis of phenomic and genomic data covering the latest software. When and where: March 10-14, 2025; Ecole Normale Superieure, 46 Rue d'Ulm, 75005 Paris - France. Faculty: Neda BARGHI, Vienna/Ploen; Nicholas BARTON, Vienna; Timothée FLUTRE, Paris; Frédéric GUILLAUME, Helsinki; Susan JOHNSTON, Edinburgh; François MALLARD, Paris Katrina McGUIGAN, Brisbane; Luisa PALLARES, Tübingen; Patrick PHILLIPS, Eugene;  Christian SCHLÖTTERER, Vienna; Bertrand SERVIN, Toulouse; Erik SVENSSON, Lund; Jacqueline SZTEPANACZ, Toronto; Henrique TEOTÓNIO, Paris; Céline TEPLITSKY, Montpellier; Pierre de VILLEMEREUIL, Paris; Ben WÖLFL, Vienna Organizers: Patrick CHARNAY, Paris; Christian SCHLÖTTERER, Vienna; Henrique TEOTÓNIO, Paris Format: The course will include introductory and research lectures in the mornings, followed by computer practicals in the afternoons. The evenings will include keynote speaker seminars and poster presentations by the students. Common lunches and dinners with the speakers and instructors will foster informal discussions. Public: The winter school is limited to 25 participants. It is open to advanced master students, PhD students,  as well as postdocs and junior scientists, with backgrounds in life sciences, physics, computer science or mathematics. Requirements: Strong interest in evolutionary genetics, and experience in file manipulation under Unix/Linux and Python or R programming. Apply by January 8, 2025, at : https://forms.office.com/e/1VySeNcY0Y. A participation fee of 150 euro includes access to materials, lunches and some dinners Monday to Friday. Please send a CV, a motivation letter and a supporting letter from a supervisor as a single pdf file with "Qlife Polygenic Adaptation Winter School2025_LASTNAME" as subject header to Aida.Fakhr@curie.fr. Informal inquiries are welcome: teotonio@bio.ens.psl.eu Additional information including a detailed program at: https://www.edu.bio.ens.psl.eu/spip.php?article287 Henrique Teotónio Institut de Biologie de l'ENS 46 Rue d'Ulm 75005 Paris, France https://www.ibens.ens.fr/?rubrique28 teotonio@bio.ens.psl.eu Henrique Teotónio (to subscribe/unsubscribe the EvolDir send mail to golding@mcmaster.ca)