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New issue alert
 
 
 
 
Bioinformatics  
Volume 40 Issue Supplement_1
 
July 2024
 
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Editorial
 
 
 
 
ISMB 2024 Proceedings border= 
 
Tijana Milenković, Yann Ponty
 
 
 
Awards Papers
 
 
 
 
The 2024 ISCB Overton Prize Award'Dr Martin Steinegger border= 
 
Mallory L Wiper
 
 
 
The 2024 ISCB Innovator Award'Dr Sui-In Lee border= 
 
Mallory L Wiper
 
 
 
The 2024 ISCB Accomplishments by a Senior Scientist Award'Dr Tandy Warnow border=  
 
Mallory L Wiper
 
 
 
The 2024 Outstanding Contributions to ISCB Award'Dr Scott Markel border= 
 
Mallory L Wiper
 
 
 
 
 
Bioinformatics Education and Citizen Science
 
 
 
 
Closing the computational biology knowledge gap': Spanish Wikipedia as a case study border= 
 
Nelly Sélem-Mojica, Tülay Karakulak, Audra Anjum, Antón Pashkov, Rafael Pérez-Estrada ...
 
 
 
Teaching bioinformatics through the analysis of SARS-CoV-2: project-based training for computer science students border= 
 
Pavlin G Poličar, Martin Špendl, Tomaž Curk, Blaž Zupan
 
 
 
Bioinformatics of Microbes and Microbiomes
 
 
 
 
Floria: fast and accurate strain haplotyping in metagenomes border= 
 
Jim Shaw, Jean-Sebastien Gounot, Hanrong Chen, Niranjan Nagarajan, Yun William Yu
 
 
 
Scalable de novo classification of antibiotic resistance of Mycobacterium tuberculosis  border= 
 
Mohammadali Serajian, Simone Marini, Jarno N Alanko, Noelle R Noyes, Mattia Prosperi ...
 
 
 
Conway'Bromage'Lyndon (CBL): an exact, dynamic representation of k -mer sets border= 
 
Igor Martayan, Bastien Cazaux, Antoine Limasset, Camille Marchet
 
 
 
 
Reference-free structural variant detection in microbiomes via long-read co-assembly graphs border= 
 
Kristen D Curry, Feiqiao Brian Yu, Summer E Vance, Santiago Segarra, Devaki Bhaya ...
 
 
 
Towards more accurate microbial source tracking via non-negative matrix factorization (NMF) border= 
 
Ziyi Huang, Dehan Cai, Yanni Sun
 
 
 
Biomedical Informatics
 
 
 
 
PhiHER2: phenotype-informed weakly supervised model for HER2 status prediction from pathological images border= 
 
Chaoyang Yan, Jialiang Sun, Yiming Guan, Jiuxin Feng, Hong Liu ...
 
 
 
CODEX: COunterfactual Deep learning for the in silico EXploration of cancer cell line perturbations border= 
 
Stefan Schrod, Helena U Zacharias, Tim Beißbarth, Anne-Christin Hauschild, Michael Altenbuchinger
 
 
 
Adaptive digital tissue deconvolution border=  
 
Franziska Görtler, Malte Mensching-Buhr, Ørjan Skaar, Stefan Schrod, Thomas Sterr ...
 
 
 
Approximating facial expression effects on diagnostic accuracy via generative AI in medical genetics border= 
 
Tanviben Patel, Amna A Othman, Ömer Sümer, Fabio Hellman, Peter Krawitz ...
 
 
 
Improving medical reasoning through retrieval and self-reflection with retrieval-augmented large language models border= 
 
Minbyul Jeong, Jiwoong Sohn, Mujeen Sung, Jaewoo Kang
 
 
 
Transfer learning of condition-specific perturbation in gene interactions improves drug response prediction border= 
 
Dongmin Bang, Bonil Koo, Sun Kim
 
 
 
Modeling metastatic progression from cross-sectional cancer genomics data border=  
 
Kevin Rupp, Andreas Lösch, Yanren Linda Hu, Chenxi Nie, Rudolf Schill ...
 
 
 
Integrating patients in time series clinical transcriptomics data border=  
 
Euxhen Hasanaj, Sachin Mathur, Ziv Bar-Joseph
 
 
 
Representing mutations for predicting cancer drug response border=  
 
Patrick Wall, Trey Ideker
 
 
 
TA-RNN: an attention-based time-aware recurrent neural network architecture for electronic health records border= 
 
Mohammad Al Olaimat, Serdar Bozdag
 
 
 
Oncotree2vec ' a method for embedding and clustering of tumor mutation trees border=  
 
Monica-Andreea Baciu-Drăgan, Niko Beerenwinkel
 
 
 
Probabilistic pathway-based multimodal factor analysis border=  
 
Alexander Immer, Stefan G Stark, Francis Jacob, Ximena Bonilla, Tinu Thomas ...
 
 
 
Equity and Diversity
 
 
 
 
Epidemiological topology data analysis links severe COVID-19 to RAAS and hyperlipidemia associated metabolic syndrome conditions border= 
 
Daniel Platt, Aritra Bose, Kahn Rhrissorrakrai, Chaya Levovitz, Laxmi Parida
 
 
 
Evolutionary, Comparative and Population Genomics
 
 
 
 
A machine-learning-based alternative to phylogenetic bootstrap border= 
 
Noa Ecker, Dorothée Huchon, Yishay Mansour, Itay Mayrose, Tal Pupko
 
 
 
Joint inference of cell lineage and mitochondrial evolution from single-cell sequencing data border= 
 
Palash Sashittal, Viola Chen, Amey Pasarkar, Benjamin J Raphael
 
 
 
Maximum likelihood phylogeographic inference of cell motility and cell division from spatial lineage tracing data border= 
 
Uyen Mai, Gary Hu, Benjamin J Raphael
 
 
 
Median and small parsimony problems on RNA trees border=  
 
Bertrand Marchand, Yoann Anselmetti, Manuel Lafond, Aïda Ouangraoua
 
 
 
General Computational Biology
 
 
 
 
An empirical study on KDIGO-defined acute kidney injury prediction in the intensive care unit border= 
 
Xinrui Lyu, Bowen Fan, Matthias Hüser, Philip Hartout, Thomas Gumbsch ...
 
 
 
SpecEncoder: deep metric learning for accurate peptide identification in proteomics border= 
 
Kaiyuan Liu, Chenghua Tao, Yuzhen Ye, Haixu Tang
 
 
 
BioCoder: a benchmark for bioinformatics code generation with large language models border= 
 
Xiangru Tang, Bill Qian, Rick Gao, Jiakang Chen, Xinyun Chen ...
 
 
 
Genome Sequence Analysis
 
 
 
 
Optimal phylogenetic reconstruction of insertion and deletion events border= 
 
Sanjana Tule, Gabriel Foley, Chongting Zhao, Michael Forbes, Mikael Bodén
 
 
 
Sigmoni: classification of nanopore signal with a compressed pangenome index border=  
 
Vikram S Shivakumar, Omar Y Ahmed, Sam Kovaka, Mohsen Zakeri, Ben Langmead
 
 
 
Forseti : a mechanistic and predictive model of the splicing status of scRNA-seq reads border= 
 
Dongze He, Yuan Gao, Spencer Skylar Chan, Natalia Quintana-Parrilla, Rob Patro
 
 
 
Accurate assembly of multiple RNA-seq samples with Aletsch border=  
 
Qian Shi, Qimin Zhang, Mingfu Shao
 
 
 
Learning locality-sensitive bucketing functions border=  
 
Xin Yuan, Ke Chen, Xiang Li, Qian Shi, Mingfu Shao
 
 
 
Fast multiple sequence alignment via multi-armed bandits border=  
 
Kayvon Mazooji, Ilan Shomorony
 
 
 
Label-guided seed-chain-extend alignment on annotated De Bruijn graphs border=  
 
Harun Mustafa, Mikhail Karasikov, Nika Mansouri Ghiasi, Gunnar Rätsch, André Kahles
 
 
 
Macromolecular Sequence, Structure, and Function
 
 
 
 
RiboDiffusion: tertiary structure-based RNA inverse folding with generative diffusion models border= 
 
Han Huang, Ziqian Lin, Dongchen He, Liang Hong, Yu Li
 
 
 
MolLM : a unified language model for integrating biomedical text with 2D and 3D molecular representations border= 
 
Xiangru Tang, Andrew Tran, Jeffrey Tan, Mark B Gerstein
 
 
 
MolPLA: a molecular pretraining framework for learning cores, R-groups and their linker joints border= 
 
Mogan Gim, Jueon Park, Soyon Park, Sanghoon Lee, Seungheun Baek ...
 
 
 
Unveil cis -acting combinatorial mRNA motifs by interpreting deep neural network border= 
 
Xiaocheng Zeng, Zheng Wei, Qixiu Du, Jiaqi Li, Zhen Xie ...
 
 
 
Integration of background knowledge for automatic detection of inconsistencies in gene ontology annotation border= 
 
Jiyu Chen, Benjamin Goudey, Nicholas Geard, Karin Verspoor
 
 
 
Predicting protein functions using positive-unlabeled ranking with ontology-based priors border= 
 
Fernando Zhapa-Camacho, Zhenwei Tang, Maxat Kulmanov, Robert Hoehndorf
 
 
 
A learned score function improves the power of mass spectrometry database search border= 
 
Varun Ananth, Justin Sanders, Melih Yilmaz, Bo Wen, Sewoong Oh ...
 
 
 
DDAffinity: predicting the changes in binding affinity of multiple point mutations using protein 3D structure border= 
 
Guanglei Yu, Qichang Zhao, Xuehua Bi, Jianxin Wang
 
 
 
An algorithm for decoy-free false discovery rate estimation in XL-MS/MS proteomics border= 
 
Yisu Peng, Shantanu Jain, Predrag Radivojac
 
 
 
Partial RNA design border= 
 
Frederic Runge, Jörg Franke, Daniel Fertmann, Rolf Backofen, Frank Hutter
 
 
 
Regulatory and Functional Genomics
 
 
 
 
Optimal sequencing budget allocation for trajectory reconstruction of single cells border= 
 
Noa Moriel, Edvin Memet, Mor Nitzan
 
 
 
AttentionPert: accurately modeling multiplexed genetic perturbations with multi-scale effects border= 
 
Ding Bai, Caleb N Ellington, Shentong Mo, Le Song, Eric P Xing
 
 
 
Predicting single-cell cellular responses to perturbations using cycle consistency learning border= 
 
Wei Huang, Hui Liu
 
 
 
Enhancing Hi-C contact matrices for loop detection with Capricorn: a multiview diffusion model border= 
 
Tangqi Fang, Yifeng Liu, Addie Woicik, Minsi Lu, Anupama Jha ...
 
 
 
A count-based model for delineating cell'cell interactions in spatial transcriptomics data border= 
 
Hirak Sarkar, Uthsav Chitra, Julian Gold, Benjamin J Raphael
 
 
 
scGrapHiC: deep learning-based graph deconvolution for Hi-C using single cell gene expression border= 
 
Ghulam Murtaza, Byron Butaney, Justin Wagner, Ritambhara Singh
 
 
 
Systems Biology and Networks
 
 
 
 
Biomarker identification by interpretable maximum mean discrepancy border= 
 
Michael F Adamer, Sarah C Brüningk, Dexiong Chen, Karsten Borgwardt
 
 
 
Identifying new cancer genes based on the integration of annotated gene sets via hypergraph neural networks border= 
 
Chao Deng, Hong-Dong Li, Li-Shen Zhang, Yiwei Liu, Yaohang Li ...
 
 
 
SPRITE: improving spatial gene expression imputation with gene and cell networks border= 
 
Eric D Sun, Rong Ma, James Zou
 
 
 
Deciphering high-order structures in spatial transcriptomes with graph-guided Tucker decomposition border= 
 
Charles Broadbent, Tianci Song, Rui Kuang
 
 
 
Enhancing generalizability and performance in drug'target interaction identification by integrating pharmacophore and pre-trained models border= 
 
Zuolong Zhang, Xin He, Dazhi Long, Gang Luo, Shengbo Chen
 
 
 
GraphCompass: spatial metrics for differential analyses of cell organization across conditions border= 
 
Mayar Ali, Merel Kuijs, Soroor Hediyeh-zadeh, Tim Treis, Karin Hrovatin ...
 
 
 
Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data border= 
 
Domagoj Dorešić, Stephan Grein, Jan Hasenauer
 
 
 
REUNION: transcription factor binding prediction and regulatory association inference from single-cell multi-omics data border= 
 
Yang Yang, Dana Pe'er
 
 
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