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Volume 14, Issue 9, September 2024
Investigation
Characterization and trans-generation dynamics of mitogene pool in the silver carp (Hypophthalmichthys molitrix)
An amplicon panel for high-throughput and low-cost genotyping of Pacific oyster
Modeling the evolution of Schizosaccharomyces pombe populations with multiple killer meiotic drivers
PAX3 haploinsufficiency in Maine Coon cats with dominant blue eyes and hearing loss resembling the human Waardenburg syndrome
In this study, Garces et al. investigated two lineages of DBE Maine Coon cats, the Dutch and the Topaz lines. Some of these cats are deaf. After whole-genome sequencing of two DBE cats, the authors identified a nonsense variant in PAX3 (g.205,787,310G>A). The mutant allele was absent from 461 feline genomes, and genotypes at the PAX3:c.937C>T variant perfectly co-segregated with DBE, deafness and minimal white spotting in the Dutch line cats, however it was not found in DBE cats of the Topaz lineage.
Genomic co-localization of variation affecting agronomic and human gut microbiome traits in a meta-analysis of diverse sorghum
Genome-wide association studies from spoken phenotypic descriptions: a proof of concept from maize field studies
Male-biased recombination at chromosome ends in a songbird revealed by precisely mapping crossover positions
On the evolutionary origin of discrete phenotypic plasticity
The Psathyrostachys juncea DWARF27 gene encodes an all-trans-/9-cis-beta-carotene isomerase in the control of plant branches in Arabidopsis thaliana by strigolactones
Comparative transcriptomics provides insights into molecular mechanisms of zinc tolerance in the ectomycorrhizal fungus Suillus luteus
Experimental evolution of Saccharomyces cerevisiae for caffeine tolerance alters multidrug resistance and target of rapamycin signaling pathways
A genetic screen in Drosophila uncovers a role for senseless-2 in surface glia in the peripheral nervous system to regulate CNS morphology
This paper describes a genetic screen that identified 17 genes that regulate CNS morphology in Drosophila. Genetic approaches together with whole genome sequencing analysis uncovered the molecular nature and causative lesions for 16 of these genes. Characterization of one gene, senseless-2, which encodes a zinc finger transcription factor, revealed that it is expressed and functions in surface glia in the peripheral nervous system (PNS), but not CNS, to govern CNS structure, identifying one of the first genes known to subdivide a glial subtype along the PNS-CNS axis.
Accurate genotype imputation from low-coverage whole-genome sequencing data of rainbow trout
Selection with two alleles of X-linkage and its application to the fitness component analysis of OdsH in Drosophila
Genetic constitution and variability in synthetic populations of intermediate wheatgrass, an outcrossing perennial grain crop
Understanding the genetic basis of blueberry postharvest traits to define better breeding strategies
Pathogen infection alters the gene expression landscape of transposable elements in Drosophila melanogaster
A random mutagenesis screen enriched for missense mutations in bacterial effector proteins
Adaptive genetic mechanisms in mammalian Parp1 locus
Analysis of transcriptional response in haploid and diploid Schizosaccharomyces pombe under genotoxic stress
In this study, Park and Forsburg investigate the role of ploidy on the S. pombe transcriptome in unperturbed conditions and in response to genotoxic stress. The authors find that the diploid response to MMS is muted compared to the haploid response, although the enriched pathways remain largely the same.
Characterization of mycobacteriophage Adephagia cytotoxic proteins
Transposon-sequencing (Tn-seq) of the Candida glabrata reference strain CBS138 reveals epigenetic plasticity, structural variation, and intrinsic mechanisms of resistance to micafungin
Genome Report
Genomic resources of aquatic Lepidoptera, Elophila obliteralis and Hyposmocoma kahamanoa, reveal similarities with Trichoptera in amino acid composition of major silk genes
First draft reference genome and annotation of the alternative oil species Physaria fendleri
Chromosome-scale Elaeis guineensis and E. oleifera assemblies: comparative genomics of oil palm and other Arecaceae
A chromosome-level genome assembly of the disco clam, Ctenoides ales
Chromosome-scale genome assembly and annotation of the tetraploid potato cultivar Diacol Capiro adapted to the Andean region
The Diacol Capiro potato cultivar dominates Colombian cultivation. This autotetraploid, highly heterozygous cultivar, part of the Andigenum group, adapts to diverse environments across altitudes from 1800 to 3200 meters. The study presents a high-quality chromosome-scale assembly (DC) spanning 2.369 Gb, with 48 pseudochromosomes, an N50 of 50.5 Mb, and a BUSCO score of 99.38%. Annotation identified 154,114 genes, including 2107 NLR genes. Comparative analysis with known genomes highlights its significance for advancing potato genetics and breeding in Latin America.
Nematode-resistance loci in upland cotton genomes are associated with structural differences
Copy number variation of putative nematode resistant genes within the resistance loci was identified using a parent-offspring pangenome approach comparing upland cotton varieties (G. hirsutum L.).
