Subject: New issue: Nucleic Acids Research, Volume 53, Issue 16, 9 September 2025
 
Genome Integrity, Repair and Replication
 
 
The house mouse maintains constant telomere length throughout life
Riham Smoom and others
hnRNPL'CstF64 complex: coordinating CSR and LSR in IgH locus recombination dynamics through eRNA and NHEJ regulation
Farazul Haque and others
Rad51, Rad54, and ZMM proteins antagonize the mismatch repair system to promote fertility of budding yeast intraspecies hybrid zygotes
Ya-Ling Hung and others
 
Molecular and Structural Biology
 
 
Effects of flanking regions on DNA i-motif folding and stability
Chuyang Zhang and others
Composition and RNA binding specificity of metazoan RNase MRP
Yuan Liu and others
Cryo-EM structures of the MnmE'MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Laila Maes and others
A conserved viral RNA fold enables nuclease resistance across kingdoms of life
Jeanine G Gezelle and others
Structural basis for ligand recognition in the tobramycin riboswitch
Elke Duchardt-Ferner and others
 
Nucleic Acid Enzymes
 
 
Single-molecule fluorescence reveals the DNA unwinding mechanism of mitochondrial helicase TWINKLE and its interplay with single-stranded DNA-binding proteins
Hsin-Yi Wang and others
An engineered CRISPR'Cas12i tool for efficient multiplexed genome editing
Linli Wang and others
A DNA nicking Class 1 OLD family nuclease mediates phage defense in Vibrio cholerae and is countered by a phage-encoded inhibitor
Kishen M Patel and Kimberley D Seed
Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB
Simranjeet Kaur and others
Structural basis of substrate diversity and functional evolution of archaeal RNA-splicing endonucleases
Yuna Miyata and others
 
Nucleic Acid Therapeutics
 
 
Angelman syndrome patient-derived neuron screen leads to clinical ASO rugonersen targeting UBE3A-ATS with long-lasting effect in monkeys
Ravi Jagasia and others
 
RNA and RNA-protein complexes
 
 
Nuclear Argonaute:miRNA complexes recognize target sequences within chromatin-associated RNA and silence gene expression
Cristina R Hofman and others
DEAD-box helicase intrinsically disordered domains and structural dynamics of HIV-1 RNA are required to reveal DDX3X catalytic efficiency
Nathalie Chamond and others
Ribosomal protein Rps29/uS14 contributes to 18S rRNA maturation and its abundance regulates osmotic stress response in S. cerevisiae
Ramin Zadali and others
High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes
Sophie E L Wintermans and others
HIV-2 evades restriction by ZAP through adaptations in the U3 LTR region despite increased CpG levels
Dorota Kmiec and others
The endoribonuclease Rae1 from Bacillus subtilis cleaves mRNA upstream of stalled ribosomes
Valentin Deves and others
 
Synthetic Biology and Bioengineering
 
 
Hierarchical access to encoded data on DNA nanostructures using administrator and user keys
Kuiting Chen and others
Deep learning guided programmable design of Escherichia coli core promoters from sequence architecture to strength control
Xuan Zhou and others
 
Methods
 
 
Whole-miRNome sequencing: a panel for the targeted sequencing of all human miRNA genes
Paulina Galka-Marciniak and others
An interpretable and adaptive autoencoder for efficient tissue deconvolution
Jesús de la Fuente and others
Deciphering enzymatic potential in metagenomic reads through DNA language models
R Prabakaran and Yana Bromberg
 
Corrections
 
 
Correction to ˜Base-resolution binding profile prediction of proteins on RNAs with deep learning'
Correction to ˜An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobility'
20th Open Access Anniversary

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