The new science of sleep: From cells to large-scale societies

Omer Sharon, Eti Ben Simon, Vyoma D. Shah, Tenzin Desel, Matthew P. Walker

PLOS Biology: published July 8, 2024 | https://doi.org/10.1371/journal.pbio.3002684

The immune modules conserved across the tree of life: Towards a definition of ancestral immunity

Aude Bernheim, Jean Cury, Enzo Z. Poirier

PLOS Biology: published July 15, 2024 | https://doi.org/10.1371/journal.pbio.3002717

Beyond fission and fusion—Diving into the mysteries of mitochondrial shape

Noga Preminger, Maya Schuldiner

PLOS Biology: published July 1, 2024 | https://doi.org/10.1371/journal.pbio.3002671

A new gatekeeper to control oligodendrogenesis

Tim Czopka

PLOS Biology: published July 11, 2024 | https://doi.org/10.1371/journal.pbio.3002691

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Activity-induced reactivity of astrocytes impairs cognition

Kirsten Bohmbach, Christian Henneberger

PLOS Biology: published July 12, 2024 | https://doi.org/10.1371/journal.pbio.3002712

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Uncovering the hidden complexity of multicellular magnetotactic bacteria

Kayla S. Stoy, William C. Ratcliff

PLOS Biology: published July 12, 2024 | https://doi.org/10.1371/journal.pbio.3002695

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When size matters: A novel compact Cas12a variant for in vivo genome editing

Felix Bubeck, Dirk Grimm

PLOS Biology: published July 17, 2024 | https://doi.org/10.1371/journal.pbio.3002637

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Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects

Yevgeniy Plavskin, Maria Stella de Biase, Naomi Ziv, Libuše Janská, Yuan O. Zhu, David W. Hall, Roland F. Schwarz, Daniel Tranchina, Mark L. Siegal

PLOS Biology: published July 1, 2024 | https://doi.org/10.1371/journal.pbio.3002698

Multicellular magnetotactic bacteria are genetically heterogeneous consortia with metabolically differentiated cells

George A. Schaible, Zackary J. Jay, John Cliff, Frederik Schulz, Colin Gauvin, Danielle Goudeau, Rex R. Malmstrom, S. Emil Ruff, Virginia Edgcomb, Roland Hatzenpichler

PLOS Biology: published July 11, 2024 | https://doi.org/10.1371/journal.pbio.3002638

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Dopamine and acetylcholine have distinct roles in delay- and effort-based decision-making in humans

Mani Erfanian Abdoust, Monja Isabel Froböse, Alfons Schnitzler, Elisabeth Schreivogel, Gerhard Jocham

PLOS Biology: published July 12, 2024 | https://doi.org/10.1371/journal.pbio.3002714

Limb-related sensory prediction errors and task-related performance errors facilitate human sensorimotor learning through separate mechanisms

Anushka Oza, Adarsh Kumar, Apoorva Sharma, Pratik K. Mutha

PLOS Biology: published July 3, 2024 | https://doi.org/10.1371/journal.pbio.3002703

Goal-directed attention transforms both working and long-term memory representations in the human parietal cortex

Huinan Hu, Anqi Li, Liang Zhang, Chuqi Liu, Liang Shi, Xiaojing Peng, Tong Li, Yu Zhou, Gui Xue

PLOS Biology: published July 15, 2024 | https://doi.org/10.1371/journal.pbio.3002721

Retrieval of contextual memory can be predicted by CA3 remapping and is differentially influenced by NMDAR activity in rat hippocampus subregions

Magdalena Miranda, Azul Silva, Juan Facundo Morici, Marcos Antonio Coletti, Mariano Belluscio, Pedro Bekinschtein

PLOS Biology: published July 1, 2024 | https://doi.org/10.1371/journal.pbio.3002706

Dominant activities of fear engram cells in the dorsal dentate gyrus underlie fear generalization in mice

Kun Cui, Xuetao Qi, Zilong Liu, Weiqi Sun, Peijie Jiao, Chang Liu, Jifu Tong, Xiaoyan Sun, Haojie Sun, Su Fu, Jiaxin Wang, Yawen Zheng, Tianyu Liu, Shuang Cui, Fengyu Liu, Jian Mao, Jie Zheng, You Wan, Ming Yi

PLOS Biology: published July 12, 2024 | https://doi.org/10.1371/journal.pbio.3002679

Deep brain stimulation of the Tbr1-deficient mouse model of autism spectrum disorder at the basolateral amygdala alters amygdalar connectivity, whole-brain synchronization, and social behaviors

Tsan-Ting Hsu, Tzyy-Nan Huang, Chien-Yao Wang, Yi-Ping Hsueh

PLOS Biology: published July 16, 2024 | https://doi.org/10.1371/journal.pbio.3002646

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease

Rikesh M. Rajani, Robert Ellingford, Mariam Hellmuth, Samuel S. Harris, Orjona S. Taso, David Graykowski, Francesca Kar Wey Lam, Charles Arber, Emre Fertan, John S. H. Danial, Matthew Swire, Marcus Lloyd, Tatiana A. Giovannucci, Mathieu Bourdenx, David Klenerman, Robert Vassar, Selina Wray, Carlo Sala Frigerio, Marc Aurel Busche

PLOS Biology: published July 23, 2024 | https://doi.org/10.1371/journal.pbio.3002727

Aberrant activation of hippocampal astrocytes causes neuroinflammation and cognitive decline in mice

Jae-Hong Kim, Nakamura Michiko, In-Sun Choi, Yujung Kim, Ji-Young Jeong, Maan-Gee Lee, Il-Sung Jang, Kyoungho Suk

PLOS Biology: published July 11, 2024 | https://doi.org/10.1371/journal.pbio.3002687

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KCTD proteins regulate morphine dependence via heterologous sensitization of adenylyl cyclase 1 in mice

Zhong Ding, Chunsheng Zhang, Huicui Yang, Jiaojiao Chen, Zhiruo Sun, Xuechu Zhen

PLOS Biology: published July 15, 2024 | https://doi.org/10.1371/journal.pbio.3002716

miR-203 secreted in extracellular vesicles mediates the communication between neural crest and placode cells required for trigeminal ganglia formation

Yanel E. Bernardi, Estefania Sanchez-Vasquez, Rocío Belén Márquez, Michael L. Piacentino, Hugo Urrutia, Izadora Rossi, Karina L. Alcântara Saraiva, Antonio Pereira-Neves, Marcel I. Ramirez, Marianne E. Bronner, Natalia de Miguel, Pablo H. Strobl-Mazzulla

PLOS Biology: published July 22, 2024 | https://doi.org/10.1371/journal.pbio.3002074

Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway

Ben Ewen-Campen, Norbert Perrimon

PLOS Biology: published July 24, 2024 | https://doi.org/10.1371/journal.pbio.3002547

Mapping mutational fitness effects across the coxsackievirus B3 proteome reveals distinct profiles of mutation tolerability

Beatriz Álvarez-Rodríguez, Sebastian Velandia-Álvarez, Christina Toft, Ron Geller

PLOS Biology: published July 16, 2024 | https://doi.org/10.1371/journal.pbio.3002709

Canonical and noncanonical roles of Hop1 are crucial for meiotic prophase in the fungus Sordaria macrospora

Emeline Dubois, Stéphanie Boisnard, Henri-Marc Bourbon, Kenza Yefsah, Karine Budin, Robert Debuchy, Liangran Zhang, Nancy Kleckner, Denise Zickler, Eric Espagne

PLOS Biology: published July 1, 2024 | https://doi.org/10.1371/journal.pbio.3002705

SAMD9L acts as an antiviral factor against HIV-1 and primate lentiviruses by restricting viral and cellular translation

Alexandre Legrand, Clara Dahoui, Clément De La Myre Mory, Kodie Noy, Laura Guiguettaz, Margaux Versapuech, Clara Loyer, Margaux Pillon, Mégane Wcislo, Laurent Guéguen, Clarisse Berlioz-Torrent, Andrea Cimarelli, Mathieu Mateo, Francesca Fiorini, Emiliano P. Ricci, Lucie Etienne

PLOS Biology: published July 3, 2024 | https://doi.org/10.1371/journal.pbio.3002696

The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis

Mason A. McCool, Carson J. Bryant, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga

PLOS Biology: published July 8, 2024 | https://doi.org/10.1371/journal.pbio.3002718

Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans

Katherine S. Yanagi, Briar Jochim, Sheikh Omar Kunjo, Peter Breen, Gary Ruvkun, Nicolas Lehrbach

PLOS Biology: published July 11, 2024 | https://doi.org/10.1371/journal.pbio.3002720

Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1

Thi Tuong Vi Dang, Corinne Maufrais, Jessie Colin, Frédérique Moyrand, Isabelle Mouyna, Jean-Yves Coppée, Chinaemerem U. Onyishi, Joanna Lipecka, Ida Chiara Guerrera, Robin C. May, Guilhem Janbon

PLOS Biology: published July 25, 2024 | https://doi.org/10.1371/journal.pbio.3002724

A molecularly defined subpopulation of oligodendrocyte precursor cells controls the generation of myelinating oligodendrocytes during postnatal development

Shayan Moghimyfiroozabad, Maela A. Paul, Lea Bellenger, Fekrije Selimi

PLOS Biology: published July 10, 2024 | https://doi.org/10.1371/journal.pbio.3002655

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Signaling through the nicotinic acetylcholine receptor in the liver protects against the development of metabolic dysfunction-associated steatohepatitis

Heejin Jun, Shanshan Liu, Alexander J. Knights, Kezhou Zhu, Yingxu Ma, Jianke Gong, Ashley E. Lenhart, Xiaoling Peng, Yunying Huang, Jared P. Ginder, Christopher H. Downie, Erika Thalia Ramos, Klas Kullander, Robert T. Kennedy, X. Z. Shawn Xu, Jun Wu

PLOS Biology: published July 19, 2024 | https://doi.org/10.1371/journal.pbio.3002728

Prophage induction can facilitate the in vitro dispersal of multicellular Streptomyces structures

Hoda Jaffal, Mounia Kortebi, Pauline Misson, Paulo Tavares, Malika Ouldali, Hervé Leh, Sylvie Lautru, Virginia S. Lioy, François Lecointe, Stéphanie G. Bury-Moné

PLOS Biology: published July 25, 2024 | https://doi.org/10.1371/journal.pbio.3002725

Retrotransposon-mediated disruption of a chitin synthase gene confers insect resistance to Bacillus thuringiensis Vip3Aa toxin

Zhenxing Liu, Chongyu Liao, Luming Zou, Minghui Jin, Yinxue Shan, Yudong Quan, Hui Yao, Lei Zhang, Peng Wang, Zhuangzhuang Liu, Na Wang, Anjing Li, Kaiyu Liu, Bruce E. Tabashnik, David G. Heckel, Kongming Wu, Yutao Xiao

PLOS Biology: published July 2, 2024 | https://doi.org/10.1371/journal.pbio.3002704

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures

Bernardo Antunes, Caroline Zanchi, Paul R. Johnston, Bar Maron, Christopher Witzany, Roland R. Regoes, Zvi Hayouka, Jens Rolff

PLOS Biology: published July 2, 2024 | https://doi.org/10.1371/journal.pbio.3002692

Hyphae of the fungus Aspergillus nidulans demonstrate chemotropism to nutrients and pH

Riho Yamamoto, Hinata Miki, Ayaka Itani, Norio Takeshita

PLOS Biology: published July 30, 2024 | https://doi.org/10.1371/journal.pbio.3002726

Individual canopy tree species maps for the National Ecological Observatory Network

Ben G. Weinstein, Sergio Marconi, Alina Zare, Stephanie A. Bohlman, Aditya Singh, Sarah J. Graves, Lukas Magee, Daniel J. Johnson, Sydne Record, Vanessa E. Rubio, Nathan G. Swenson, Philip Townsend, Thomas T. Veblen, Robert A. Andrus, Ethan P. White

PLOS Biology: published July 16, 2024 | https://doi.org/10.1371/journal.pbio.3002700

A phylogeny-informed characterisation of global tetrapod traits addresses data gaps and biases

Mario R. Moura, Karoline Ceron, Jhonny J. M. Guedes, Rosana Chen-Zhao, Yanina V. Sica, Julie Hart, Wendy Dorman, Julia M. Portmann, Pamela González-del-Pliego, Ajay Ranipeta, Alessandro Catenazzi, Fernanda P. Werneck, Luís Felipe Toledo, Nathan S. Upham, João F. R. Tonini, Timothy J. Colston, Robert Guralnick, Rauri C. K. Bowie, R. Alexander Pyron, Walter Jetz

PLOS Biology: published July 11, 2024 | https://doi.org/10.1371/journal.pbio.3002658

Single-fly genome assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life

Bernard Y. Kim, Hannah R. Gellert, Samuel H. Church, Anton Suvorov, Sean S. Anderson, Olga Barmina, Sofia G. Beskid, Aaron A. Comeault, K. Nicole Crown, Sarah E. Diamond, Steve Dorus, Takako Fujichika, James A. Hemker, Jan Hrcek, Maaria Kankare, Toru Katoh, Karl N. Magnacca, Ryan A. Martin, Teruyuki Matsunaga, Matthew J. Medeiros, Danny E. Miller, Scott Pitnick, Michele Schiffer, Sara Simoni, Tessa E. Steenwinkel, Zeeshan A. Syed, Aya Takahashi, Kevin H-C. Wei, Tsuya Yokoyama, Michael B. Eisen, Artyom Kopp, Daniel Matute, Darren J. Obbard, Patrick M. O’Grady, Donald K. Price, Masanori J. Toda, Thomas Werner, Dmitri A. Petrov

PLOS Biology: published July 18, 2024 | https://doi.org/10.1371/journal.pbio.3002697

FURNA: A database for functional annotations of RNA structures

Chengxin Zhang, Lydia Freddolino

PLOS Biology: published July 29, 2024 | https://doi.org/10.1371/journal.pbio.3002476

“Best Paper” awards lack transparency, inclusivity, and support for Open Science

Malgorzata Lagisz, Joanna Rutkowska, Upama Aich, Robert M. Ross, Manuela S. Santana, Joshua Wang, Nina Trubanová, Matthew J. Page, Andrew Adrian Yu Pua, Yefeng Yang, Bawan Amin, April Robin Martinig, Adrian Barnett, Aswathi Surendran, Ju Zhang, David N. Borg, Jafsia Elisee, James G. Wrightson, Shinichi Nakagawa

PLOS Biology: published July 23, 2024 | https://doi.org/10.1371/journal.pbio.3002715

Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli

Rowan Green, Hejie Wang, Carol Botchey, Siu Nam Nancy Zhang, Charles Wadsworth, Francesca Tyrrell, James Letton, Andrew J. McBain, Pawel Paszek, Rok Krašovec, Christopher G. Knight

PLOS Biology: published July 15, 2024 | https://doi.org/10.1371/journal.pbio.3002711

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Behavioral adjustment of C. elegans to mechanosensory loss requires intact mechanosensory neurons

Michal Staum, Ayelet-Chen Abraham, Reema Arbid, Varun Sanjay Birari, Matanel Dominitz, Ithai Rabinowitch

PLOS Biology: published July 18, 2024 | https://doi.org/10.1371/journal.pbio.3002729

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Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

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PLOS Biology: published July 31, 2024 | https://doi.org/10.1371/journal.pbio.3002673

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