Behavioral convergence under urbanization: An overlooked dimension of biotic homogenization

Peter Mikula, Daniel T. Blumstein, Piotr Tryjanowski

PLOS Biology: published March 2, 2026 | https://doi.org/10.1371/journal.pbio.3003689

Expanding invasive species impact assessments to the ecosystem level with EEICAT

Laís Carneiro, Daniel Pincheira-Donoso, Boris Leroy, Sandro Bertolino, Morelia Camacho-Cervantes, Ross N. Cuthbert, Alok Bang, Jane A. Catford, Josie South, Steven J. Cooke, Elena Angulo, Franck Courchamp

PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003665

How does the cerebellum contribute to cognitive functions?

Jörn Diedrichsen, Samuel D. McDougle

PLOS Biology: published March 23, 2026 | https://doi.org/10.1371/journal.pbio.3003688

Deep learning in biology faces a transferability crisis

Thomas A. O’Shea-Wheller, Katie I. Murray

PLOS Biology: published March 3, 2026 | https://doi.org/10.1371/journal.pbio.3003656

Measures to strengthen international biosafety and biosecurity practices

Etienne Decroly, Patrick Berche, Ali Asy, Maggie L. Bartlett, Åsa Szekely Björndal, Christian Brechot, Patrick G. Casey, Patrick Couvreur, Maria J. Espona, Claudia Filippone, Diah Iskandriati, Wilmot James, Rafael Elias Marques, Zabta Khan Shinwari, Bernadett Pályi, Dana Perkins, Kathrin Summermatter, Olivier Vandenberg, Kurt Zatloukal, Jonathan Ewbank

PLOS Biology: published March 18, 2026 | https://doi.org/10.1371/journal.pbio.3003691

Developing monoclonal antibody therapies for measles could lead to adverse pathogen evolution

David A. Kennedy

PLOS Biology: published March 3, 2026 | https://doi.org/10.1371/journal.pbio.3003701

Does adaption require a complex symphony or just “three chords and the truth?”

Klas I. Udekwu, Christopher J. Marx

PLOS Biology: published March 27, 2026 | https://doi.org/10.1371/journal.pbio.3003679

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Host jumps need not be common just because spillover is

Mete Yuksel, Nicole Mideo

PLOS Biology: published March 20, 2026 | https://doi.org/10.1371/journal.pbio.3003682

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Why do we have so many different transcripts?

Laurence D. Hurst

PLOS Biology: published March 20, 2026 | https://doi.org/10.1371/journal.pbio.3003686

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TDP-43 is coming to the cottage: A new tool to study neurodegenerative diseases

Stephanie L. Rayner, Aaron D. Gitler

PLOS Biology: published March 25, 2026 | https://doi.org/10.1371/journal.pbio.3003697

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Thaliacean tunicates, vertebrate sisters regained lifelong mobility

Yasunori Sasakura

PLOS Biology: published March 18, 2026 | https://doi.org/10.1371/journal.pbio.3003674

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Selection for growth drives the emergence of genetic heredity in protocells

Raquel Nunes Palmeira, Marco Colnaghi, Andrew Pomiankowski, Nick Lane

PLOS Biology: published March 30, 2026 | https://doi.org/10.1371/journal.pbio.3003544

Genotype-fitness mapping of adaptive mutants reveals shifting low-dimensional structure across divergent environments

Olivia M. Ghosh, Grant Kinsler, Benjamin H. Good, Dmitri A. Petrov

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003618

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A bacterial ecocline in Klebsiella pneumoniae may explain its backboned phylogeny

Siqi Liu, Sarah L. Svensson, Daniel Falush

PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003672

Plug-and-play evolution of the Klebsiella pneumoniae capsule locus enables serotype exchange across genetic backgrounds

Julie Le Bris, Hugo Varet, Eduardo P. C. Rocha, Olaya Rendueles

PLOS Biology: published March 25, 2026 | https://doi.org/10.1371/journal.pbio.3003724

Sub-daily virus sampling at the Bermuda Atlantic Time Series reveals diel and depth-structured population dynamics without community-level shifts

Alfonso Carrillo, Emily Hageman, Lauren Chittick, Anna I. Mackey, Kimberley S. Ndlovu, Funing Tian, Naomi E. Gilbert, Daniel Muratore, Dean Vik, Gary R. LeCleir, Christine Sun, Ho B. Jang, Ricardo R. Pavan, Joshua S. Weitz, Steven W. Wilhelm, Matthew B. Sullivan

PLOS Biology: published March 6, 2026 | https://doi.org/10.1371/journal.pbio.3003474

Social compatibility in opposite-sex prairie vole pairs is modulated by early-life sleep experience

Lezio S. Bueno-Junior, Noah E. P. Milman, Carolyn E. Jones-Tinsley, Anjesh Ghimire, Peyton T. Wickham, Yujia Hu, Bing Ye, Miranda M. Lim, Brendon O. Watson

PLOS Biology: published March 27, 2026 | https://doi.org/10.1371/journal.pbio.3003434

Self-allocation bias in performance-based cooperative decisions is driven by self-interest rather than distorted performance encoding

Sihui Zhang, Xue Yong, Yina Ma, Christoph W. Korn

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003694

Frontotemporal network interactions causally support rapid concreteness judgments during reading

Elliot Murphy, Oscar Woolnough, Cale W. Morse, Xavier Scherschligt, Nitin Tandon

PLOS Biology: published March 25, 2026 | https://doi.org/10.1371/journal.pbio.3003723

Immersive NREM2 dreaming preserves subjective sleep depth against declining sleep pressure

Adriana Michalak, Davide Marzoli, Francesco Pietrogiacomi, Damiana Bergamo, Valentina Elce, Bianca Pedreschi, Giorgia Mosca, Alessandro Navari, Michele Emdin, Emiliano Ricciardi, Giacomo Handjaras, Giulio Bernardi

PLOS Biology: published March 24, 2026 | https://doi.org/10.1371/journal.pbio.3003683

Dynamic expectation strength and precision shape human pain perception through shared and dissociable α-oscillatory mechanisms

Jia Li, Shihao Chen, Libo Zhang, Lingling Weng, Xinxin Lin, Yiheng Tu, Weiwei Peng

PLOS Biology: published March 2, 2026 | https://doi.org/10.1371/journal.pbio.3003675

The retrieval of previously learned motor memories is facilitated by the reinstatement of default mode network manifold structures

Ali Rezaei, Corson N. Areshenkoff, Daniel J. Gale, Emily R. Oby, Jonathan Smallwood, J. Randall Flanagan, Jeffrey D. Wammes, Jason P. Gallivan

PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003684

Pharmacological and non-pharmacological methods of inducing wakefulness activate distinct neural populations in the mouse brain

Renato Maciel, Justin Malcey, Kylian Gautier, Amarine Chancel, Blandine Duval, Théo Brunel, Patrice Fort, Claudio Marcos Queiroz, Pierre-Hervé Luppi

PLOS Biology: published March 19, 2026 | https://doi.org/10.1371/journal.pbio.3003622

Three-dimensional scene boundary representations for wall orientation and distance are represented distinctly in the human visual cortex

Yichen Wu, Sheng Li

PLOS Biology: published March 25, 2026 | https://doi.org/10.1371/journal.pbio.3003541

Neuronal populations across the cortex underlie discrete, categorical, and subjective representations of visual durations

Valeria Centanino, Gianfranco Fortunato, Domenica Bueti

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003704

Prenatal and early postnatal periods differentially shape the maturation of human cortical microstructure and myelin

Thanos Tsigaras, Juergen Dukart, Stuart Oldham, Simon B. Eickhoff, Casey Paquola

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003722

Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex

Osman Akan, Varnan Chandreswaran, Henry D. Soldan, Anne Bierbrauer, Nikolai Axmacher, Oliver T. Wolf, Christian J. Merz

PLOS Biology: published March 12, 2026 | https://doi.org/10.1371/journal.pbio.3003661

Thalamic reticular neurons provide cell type-specific modulation of sound processing in the auditory thalamus

Solymar Rolón-Martínez, Austin J. Mendoza, Christopher F. Angeloni, Nathan W. Vogler, Audrey C. Drotos, Mark Aizenberg, Ruoyi Chen, Kaylie Vu, Julie S. Haas, Maria N. Geffen

PLOS Biology: published March 12, 2026 | https://doi.org/10.1371/journal.pbio.3003693

Behavioral engagement facilitates auditory neuron responses beyond their receptive fields

Chenggang Chen, Evan D. Remington, Xiaoqin Wang

PLOS Biology: published March 13, 2026 | https://doi.org/10.1371/journal.pbio.3003707

A GABAergic network from AVP- to VIP-neurons in the suprachiasmatic nucleus sets the timing of circadian behavior rhythms

Yubo Peng, Yusuke Tsuno, Takashi Maejima, Mohan Wang, Jaehun Jung, Ayako Matsui, Michihiro Mieda

PLOS Biology: published March 9, 2026 | https://doi.org/10.1371/journal.pbio.3003706

Ischemic stroke triggers brain-wide synaptic remodeling within four hours

Huanhuan Chen, Ye Wei, Luminiţa Ruje, Fusheng Du, Zhendong Feng, Qi Wan, Mikhail Spivakov, Oleg O. Glebov

PLOS Biology: published March 2, 2026 | https://doi.org/10.1371/journal.pbio.3003608

Oligomeric lactic acid nanoplastics induce intrauterine growth restriction in mice by disrupting GATA2-mediated placental vascular development

Jia Lv, Mengjing Wang, Changzhi Shi, Yanwei Wang, Yihao Zhang, Chang Gao, Tian-Qi Bi, Jing Yang, Youdong Xu, Qunan Wang, Hua Wang, De-Xiang Xu, Mingliang Fang, Yichao Huang

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003676

Fine-tuning ERK activity enables proliferation-differentiation balance during lineage specification of human embryonic stem cells

Chenyang Ma, Weikang Meng, Jinghan Huang, Wanling Zheng, Xiao Xu, Tao Cheng, Zhengyi Li, Yang Liu, Hao Shen, Feng He, Alessandro Esposito, Pengfei Xu, Ashok Venkitaraman, Jun Ma, Heng Xu, Hongqing Liang

PLOS Biology: published March 17, 2026 | https://doi.org/10.1371/journal.pbio.3003711

Gpc3 selectively suppresses subcutaneous adipogenesis in diet-induced obesity

Yan Li, Ming Tao, Carlos F. Ibáñez, Meng Xie

PLOS Biology: published March 4, 2026 | https://doi.org/10.1371/journal.pbio.3003700

USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice

Siyang Wu, Ruixiu Cao, Xiaolan Huang, Qiongni Feng, Yajuan Zhang, Hong Gao, Bangbao Tao, Ji Liang, Weiwei Yang

PLOS Biology: published March 12, 2026 | https://doi.org/10.1371/journal.pbio.3003698

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Cell cycle dynamics regulate H3K27 and H3K9 histone modifications in Drosophila

Liyne Nogay, Ananthakrishnan Vijayakumar Maya, Lara Heckmann, Francesco Cardamone, Isabelle Grass, Aakriti Singh, Anna Frey, Laurin Ernst, Nicola Iovino, Anne-Kathrin Classen

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003371

Disrupting CD22-cis-ligand interactions ameliorates type 1 diabetes and graft rejection by expanding regulatory B cells

Wang Long, Ayaka Endo, Hashadi Nadeesha Walakulu Gamage, Tianyi Yang, Toru Suzuki, Takeshi Nitta, Hiromu Takematsu, Kenya Honda, Masatake Asano, Takeshi Tsubata

PLOS Biology: published March 24, 2026 | https://doi.org/10.1371/journal.pbio.3003681

The Rpd3 histone deacetylase is a critical regulator of temperature-mediated morphogenesis and virulence in the human fungal pathogen Histoplasma

Nebat Ali, Mark Voorhies, Rosa A. Rodriguez, Anita Sil

PLOS Biology: published March 17, 2026 | https://doi.org/10.1371/journal.pbio.3003341

Distinct Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe

Sajjita Saha, Aiswarya Sajeevan, Laura Merlini, Vincent Vincenzetti, Sophie G. Martin

PLOS Biology: published March 19, 2026 | https://doi.org/10.1371/journal.pbio.3003712

Transposable elements contribute substantially to naturally occurring genetic lethality in Drosophila melanogaster

Sarah B. Marion, Katrina Focht, Iman Hamid, Edwin S. Iversen, Hannah John, Brenda Manzano-Winkler, Amber Navarra, Saniya Pangare, Mehrnaz Zarei, Mohamed A. F. Noor

PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003467

Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs

Yu-Ying Phoebe Hsieh, Ian P. O’Keefe, Zeqi Wang, Wanting Sun, Hyojik Yang, Linda M. Vu, Nicole E. Smalley, Robert K. Ernst, Ajai A. Dandekar, Harmit S. Malik

PLOS Biology: published March 3, 2026 | https://doi.org/10.1371/journal.pbio.3003673

Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci

Guillaume Cerckel, Denis Dereinne, Laura Ledesma-García, Vincent Meuric, Benoît Desguin, Johann Mignolet, Patrice Soumillion, Pascal Hols

PLOS Biology: published March 13, 2026 | https://doi.org/10.1371/journal.pbio.3003718

Engineered romidepsin biosynthetic pathways in Escherichia coli Nissle 1917 improve the efficacy of bacteria-mediated cancer therapy

Chenghao Ma, Geng Li, Tao Sun, Ximi Tang, Tong Qiu, Jingwen Song, Hailong Wang, Youming Zhang, Tianyu Jiang

PLOS Biology: published March 17, 2026 | https://doi.org/10.1371/journal.pbio.3003657

Systematic identification of Salmonella T6SS effectors uncovers diverse new families and lipid-targeting activities

Gianlucca G. Nicastro, Stephanie Sibinelli-Sousa, Julia T. Hespanhol, Thomas W. C. Santos, Joseph P. Munoz, Rosangela S. Santos, Blanca M. Perez-Sepulveda, Sayuri Miyamoto, L. Aravind, Robson F. de Souza, Ethel Bayer-Santos

PLOS Biology: published March 17, 2026 | https://doi.org/10.1371/journal.pbio.3003680

Pathogen host jump risk is not predicted by spillover rate, but rather by novelty

Brandon J. Simony, David A. Kennedy

PLOS Biology: published March 19, 2026 | https://doi.org/10.1371/journal.pbio.3003640

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Cis-regulatory evolution of Wnt family genes contributes to a morphological difference between silkworm species

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PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003605

Biofilm spatial structure and superinfection immunity modulate inter-phage competition

James B. Winans, Carey D. Nadell

PLOS Biology: published March 31, 2026 | https://doi.org/10.1371/journal.pbio.3003737

Eye movements reflect memory-related theta activity in the human brain

Humza N. Zubair, Matthias Stangl, Uros Topalovic, Cory Inman, Martin Seeber, Sonja Hiller, Vikram R. Rao, Casey H. Halpern, Dawn Eliashiv, Itzhak Fried, Nanthia Suthana

PLOS Biology: published March 16, 2026 | https://doi.org/10.1371/journal.pbio.3003695

Glutamatergic projections from the substantia nigra pars reticulata to the dorsal raphe nucleus regulate male social hierarchies

Yanzhu Fan, Shaoxiang Ge, Lidi Lu, Wenjun Niu, Zhiyue Wang, Xiaoguo Jiao, Guangzhan Fang

PLOS Biology: published March 3, 2026 | https://doi.org/10.1371/journal.pbio.3003687

Curvature of the Drosophila corneal lens depends on localized chitin secretion

Neha Ghosh, Eva Rojo-Iost, Jessica E. Treisman

PLOS Biology: published March 20, 2026 | https://doi.org/10.1371/journal.pbio.3003725

The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice

Julia C. Johnstone, Robert Mitchell, Timothy J. Vyse, Alexander J. Clarke

PLOS Biology: published March 5, 2026 | https://doi.org/10.1371/journal.pbio.3003342

Structures of the human glucose-6-phosphate transporter provide insights into its transport cycle and substrate recognition

Wanqin Zhang, Haizhan Jiao, Jingchuan Xue, Jiao Zhou, Yuye Wang, Qi Pan, Yuting Guo, Geshu Zhang, Hongli Hu, Xue Guo

PLOS Biology: published March 30, 2026 | https://doi.org/10.1371/journal.pbio.3003731

Comparative embryogenesis of two salp species reveals rogue development and evolutionary divergence from sessile tunicates

Marie Lebel, Alexandre Alié, Patrick Lemaire, Stefano Tiozzo

PLOS Biology: published March 17, 2026 | https://doi.org/10.1371/journal.pbio.3003636

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PLOS Biology: published March 24, 2026 | https://doi.org/10.1371/journal.pbio.3003662

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Tom Tregenza, Rolando Rodríguez-Muñoz, Alfredo F. Ojanguren, Paul Hopwood, Jelle J. Boonekamp

PLOS Biology: published March 10, 2026 | https://doi.org/10.1371/journal.pbio.3003713

Translocation of bacteria from the gut to the brain in mice

Manoj Thapa, Anuradha Kumari, Chui-Yoke Chin, Jacob E. Choby, Elahe Akbari, Bikash Bogati, Fengzhi Jin, Elise Furr, Daniel M. Chopyk, Nitya Koduri, Andrew Pahnke, Theodore L. Burns, Elizabeth J. Elrod, Eileen M. Burd, David S. Weiss, Arash Grakoui

PLOS Biology: published March 12, 2026 | https://doi.org/10.1371/journal.pbio.3003652

Evidence for genetically-based sperm discrimination in the vaginal tract of a primate species

Rachel M. Petersen, Lee (Emily) M. Nonnamaker, Jaclyn A. Anderson, Christina M. Bergey, Christian Roos, Amanda D. Melin, James P. Higham

PLOS Biology: published March 31, 2026 | https://doi.org/10.1371/journal.pbio.3003699

Transcript diversity reflects deleterious RNA processing errors shaped by population size in metazoans

Kai Mi, Lili Guan, Bandhan Sarker, Siliang Song, Tianjiao Zhou, Hongliang Yi, Jianzhi Zhang, Chuan Xu

PLOS Biology: published March 19, 2026 | https://doi.org/10.1371/journal.pbio.3003671

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Véronique Kiermer, Kirsten Bibbins-Domingo, Magdalena Skipper

PLOS Biology: published March 26, 2026 | https://doi.org/10.1371/journal.pbio.3003745