Basic research into Women’s Health should be a priority for all

Joanna Clarke, on behalf of the PLOS Biology Staff Editors

PLOS Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pbio.3003990

Encrypted immunity mediated by peptides

Zhenrun J. Zhang, Yifat Merbl, Cesar de la Fuente-Nunez

PLOS Biology: published August 19, 2026 | https://doi.org/10.1371/journal.pbio.3003914

How do anthropogenic changes affect wildlife microbiomes?

Katherine M. Lagerstrom, Andrew P. Dobson, Shane Campbell-Staton, Andrew H. Moeller

PLOS Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pbio.3003939

Is the scientific paper still a fraud?

John S. Tregoning

PLOS Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pbio.3003912

Towards a research renaissance: Empowering early career researchers through mentored AI use

Douglas R. Call, Mary Sanchez-Lanier, Ananth Kalyanaraman, Sascha H. Duttke

PLOS Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pbio.3003917

Ecological dark matter: Insect decline and the planetary monitoring gap

Justin Crocker

PLOS Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pbio.3003941

The gut takes it all: Enteroendocrine control of developmental growth

Julia B. Cordero

PLOS Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pbio.3003921

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Harnessing pathogen stress-hormone sensing for living medicines

Weston R. Whitaker

PLOS Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pbio.3003940

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grafify online: A web app for graphing and statistical analysis

Avinash R. Shenoy

PLOS Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pbio.3003909

Metabolic and developmental rate divergence between serially homologous cells underlies an evolutionary innovation in Drosophila

Ben R. Hopkins, Olga Barmina, Xinying Wang, Mandy M. Situ, Haley A. Bolanos, Shizhan Nie, Artyom Kopp

PLOS Biology: published August 24, 2026 | https://doi.org/10.1371/journal.pbio.3003964

Species-specific barriers restrict virus spillover potential across the Caenorhabditis genus

Dominik Herek, Juan C. Muñoz-Sánchez, Ana Villena-Giménez, Victoria G. Castiglioni, Santiago F. Elena

PLOS Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pbio.3003965

Polymorphisms in a bacterial signalling pathway alter evolutionary routes of antibiotic resistance in Escherichia coli

Chetna Yelpure, Saillesh Chinnaraj, Kush Topiwala, Jay Phadke, Nishad Matange

PLOS Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pbio.3003977

Neural encoding of pain is robust within but unstable between individuals

Laura Tiemann, Felix S. Bott, Elisabeth S. May, Moritz M. Nickel, Vanessa D. Hohn, Cristina Gil Ávila, Nicolò Bruna, Paul Theo Zebhauser, Markus Ploner

PLOS Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pbio.3003948

Behavioral engagement and stimulus regularities coordinate auditory-prefrontal network activity

Haoxuan Xu, Peirun Song, Hangting Ye, Ana Belén Lao-Rodríguez, Qichen Zhang, Yuying Zhai, Xuehui Bao, Ishrat Mehmood, Hisashi Tanigawa, Zhiyi Tu, Lingling Zhang, Xuan Zhao, David Pérez-González, Manuel S. Malmierca, Xiongjie Yu

PLOS Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pbio.3003966

Lateralised neural mechanisms facilitate auditory self-other distinction and coordination in human dyads

Manuel Varlet, Tomas Lenc, Sylvie Nozaradan, David Poeppel, Peter E. Keller

PLOS Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pbio.3003935

Visual motion does not bias gravity-referenced vestibular coding in the primate cerebellar nodulus and uvula

Lex J. Gómez, Robyn L. Mildren, Faisal Karmali, Kathleen E. Cullen

PLOS Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pbio.3003972

Inhibitory tone in the dentate gyrus dynamically prioritizes memory flexibility or stability by tuning a sensitivity-consistency continuum

Elena Pérez-Montoyo, José María Caramés, Raquel Garcia-Hernandez, Mónica Peralta-Cañadas, Santiago Canals, Encarni Marcos

PLOS Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pbio.3003956

The subthalamic nucleus-ventral pallidum projection targeting cholinergic circuits modulates chronic pain

Ya-Wei Ji, Xiang-Ying Xu, Qiang-Qiang Zhou, Yin-Nan Cao, Xing-Jie Zhao, Kai-Ran Zhang, Yu Han, Su Liu, Yong Niu, Chun Yang, Chunyi Zhou, Cheng Xiao

PLOS Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pbio.3003923

Microsaccadic eye movement generation is sufficient to enhance peripheral visual sensitivity

Tong Zhang, Xiaoguang Tian, Tatiana Malevich, Matthias P. Baumann, Ziad M. Hafed

PLOS Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pbio.3003968

Meal timing entrains circadian rhythms in the dorsal vagal complex, a brainstem satiety centre

Lukasz Chrobok, Charlotte Muir, Tanya Chonkria Kaur, Emily Birt, Iliana Veneri, Jingyi Kathy Li, Timna Hitrec, Michael Ambler, Anthony Edward Pickering, Hugh David Piggins

PLOS Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pbio.3003936

A nutrient-sensitive enterokine coordinates developmental plasticity through inter-organ signaling

Longwei Bai, Jacques Montagne, Cathy Isaura Ramos, François Leulier

PLOS Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pbio.3003911

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Beat- and Side-family cell-surface molecules are expressed combinatorially in the partner neurons of the olfactory circuit in Drosophila

Qichen Duan, Sumie Okuwa, Rachel Estrella, Chun Yeung, Yu-Chieh David Chen, Laura Quintana Rio, Chengcheng Du, Khanh M. Vien, Pelin Cayirlioglu Volkan

PLOS Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pbio.3003955

Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data

Marine Fontaine, M. Joaquina Delás, Meritxell Sáez, Rory J. Maizels, Elizabeth Finnie, James Briscoe, David A. Rand

PLOS Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pbio.3003953

TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development

Canan Doganli, Oskar Kaaber Thomsen, Daniel A. Baird, Yeasmeen Ali, Menachem V. K. Sarusie, Enrique Audain, Line Jeanett Jessen, Pauline Munck Truelsen, Johanne Bay Mogensen, Maria Schrøder Holm, Kateřina Apolínová, Lorenzo Buttò, Maria Diamanti, Jindřiška Leischner Fialová, Emma M. Wade, Stephen P. Robertson, Lotte Bang Pedersen, Laurent Argiro, Fabienne Lescroart, Marc-Phillip Hitz, Søren Tvorup Christensen, Lars Allan Larsen

PLOS Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pbio.3003902

Incomplete functional divergence drives MADS-box gene synergy during floral development in tomato

Natalia Gaarslev, Ying Xu, Eléonore Lizé, Irene Julca, Natasha Glover, Sebastian Soyk

PLOS Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pbio.3003946

Brachyury expression levels predict lineage potential and axis-forming ability of in vitro-derived neuromesodermal progenitors

Anahí Binagui-Casas, Anna Granés, Alberto S. Ceccarelli, Matthew French, Filip J. Wymeersch, Rosa Portero Migueles, Jennifer Annoh, Yali Huang, Eleni P. Karagianni, Frederick C. K. Wong, Raffee Wright, Anna Sophie Brumm, Daniel Lopez Ramajo, Minoru Takasato, Sally Lowell, Osvaldo Chara, Valerie Wilson

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003960

let-7 miRNA and lin-46 mRNA are essential targets of the LIN28 RNA-binding protein in Caenorhabditis elegans developmental timing regulation

Jana Brunner, Anca Neagu, Dimos Gaidatzis, Lucas J. Morales Moya, Helge Großhans

PLOS Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pbio.3003892

Asymmetric chromatin accessibility underlies anterior-posterior axis specification in moth fly embryos

Ezra E. Amiri, Muzi Li, Ayse Tenger-Trolander, Maxwell Devine, Alexander T. Julian, Koray Kasan, Sheri A. Sanders, Shelby A. Blythe, Urs Schmidt-Ott

PLOS Biology: published August 6, 2026 | https://doi.org/10.1371/journal.pbio.3003896

STRIPAK-associated greenbeard proteins DOC1 and DOC2 regulate MAK2 signaling and sexual development in Sordaria macrospora

Lucas S. Hollstein, Kerstin Schmitt, Lucas Well, André Fleißner, Oliver Valerius, Stefanie Pöggeler

PLOS Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pbio.3003969

Recognition of pathogenic bacteria by intestinal stem cells promotes adult Drosophila midgut regeneration

Bhavin Uttekar, Marie Srotyr, Sanket Sudam Ravale, Liliana Ewertowska, Rebecca Wafer, Martina Legido, Parthive H. Patel

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003951

IP₃R2-mediated inter-organelle calcium signaling suppresses melanosome degradation

Suman Saurav, Anuradha Jadon, Rajender K. Motiani

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003971

Caveolin 1 is a conserved host factor mediating Bacillus cereus hemolysin BL toxin cytolytic toxicity

Yingying Lu, Jie Liu, Chengyu Liu, Zehua Zuo, Michael Ewing, Hang Chen, Toren Finkel, Stephen H. Leppla, Shihui Liu

PLOS Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pbio.3003957

Tcf15 promotes an open nucleolar chromatin state to safeguard ribosome biogenesis and genome stability in mouse embryonic stem cells

Yu-ping Dong, Yi-Min Chen, Min Tang, Hu Zhou, Lin Wang, Ping Zheng

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003954

Oxaloacetate damages mitochondria by perturbing MIC60-dependent membrane remodeling

Jie Zhang, Qian Shan, Xin Wang, Meijiao Li, Yang Yang, Mei Duan, Ruofeng Tang, Junxiang Zhou, Fengyang Wang, Yuehui Shi, Kai Jiang, Chonglin Yang

PLOS Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pbio.3003649

Reassessment of the roles of coronin proteins as actin effectors and in signaling

Roko Gvozdenica Šipić, Haiyan Zhang, Andrii Kharin, Jerneja Koren, Viviana D’Otolo, Yuko Nariai, Takeshi Urano, Pawel Pelczar, Klemens Fröhlich, Alexander Schmidt, Urszula Brykczynska Kunzmann, Tohnyui Ndinyanka Fabrice, Alexey Baldin, Jean Pieters

PLOS Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pbio.3003904

Stress granules formed during infections with RNA viruses have significant virus-specific differences in generation and composition

Reto M. Lang, Silvio Steiner, Jenna Kelly, Anne-Christine Uldry, Pratik Dave, Sophie Braga-Lagache, Jeffrey Chao, Manfred Heller, G. Tuba Barut, Volker Thiel

PLOS Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pbio.3003363

Retracing the origin and evolution of a cryptic antimicrobial peptide within mammalian lactoferrin

Titas Sil, Caitlin H. Kowalski, Sierra Scamfer, Natalie Copeland, Matthew F. Barber

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003932

Ecological theory sheds light on plasmid diversity and dynamics

Rémi Tuffet, Emma Acacia, Charles Coluzzi, Xavier Charpentier, Thomas Koffel, Samuel Venner

PLOS Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pbio.3003918

Social interactions between people of same and different generations shape longitudinal changes in interpersonal neural synchrony, loneliness, and social connection

Ryssa Moffat, Guillaume Dumas, Emily S. Cross

PLOS Biology: published August 20, 2026 | https://doi.org/10.1371/journal.pbio.3003899

Theta oscillations tag episodic memories for sleep-dependent consolidation

Dan Denis, Zhiyi Chen, Manroop Kaur, Benjamin Clayden, Thomas Schreiner, Scott A. Cairney

PLOS Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pbio.3003938

Engineering inter-kingdom adrenergic signaling in commensals couples host stress hormone sensing to programmable biological outputs

Santosh Kumar Srivastava, Guo Wei Foo, Haosheng Shen, Yuanzhi He, Kwok Soon Wun, In Young Hwang, Michael S. Goodson, Nikhil Aggarwal, Matthew Wook Chang

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003926

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Mycodnaviridae is a clade of giant viruses that persistently infect zoosporic fungi

Jillian M. Myers, Frederik Schulz, Saleh Rahimlou, Vikas Yadav, Kevin R. Amses, David Rabern Simmons, Sheng Sun, Michelle Orozco-Quime, Joseph Heitman, Jason E. Stajich, Timothy Y. James

PLOS Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pbio.3003937

Structural insights into the outer membrane proteins PorA, OMP50 and Cj0034c from native Campylobacter jejuni membranes

Zhemin Zhang, William D. Gregor, Muslum Ilgu, Yue Yin, Philip A. Klenotic, Qijing Zhang, Edward W. Yu

PLOS Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pbio.3003961

A single-cell transcriptomic atlas reveals the emergence of medusa-specific cell states in the scyphozoan Aurelia coerulea

Oliver Link, Stefan M. Jahnel, Kristin Janicek, Daniel Guerguerian, Johanna Kraus, Juan D. Montenegro, Bob Zimmermann, Brittney Wick, Konstantin Khalturin, Alison G. Cole, Ulrich Technau

PLOS Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pbio.3003931

Developmental factors drive the compartmentalized and discontinuous maturation of the small intestinal epithelium during the early postnatal period

Johannes Schöneich, Aline Dupont, Stefan Schlößer, Mingbo Cheng, Matthias A. Schmitz, Isabel Richter, Narasimha Murthy Keshava Prasad Gubbi, Kaiyi Zhang, Tiago Maié, Asmae Laouina, Sofia Jäverfelt, Fabian Imdahl, Christophe Toussaint, Antoine-Emmanuel Saliba, Christoph Kuppe, Oliver Pabst, Thaher Pelaseyed, Ivan G. Costa, Mathias W. Hornef

PLOS Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pbio.3003212

A microRNA atlas of CD4⁺ T cell subsets in experimental autoimmune encephalomyelitis identifies regulators of disease pathogenesis

Carolina Cunha, Daniel Inácio, Paula Vargas Romero, Ana Teresa Pais, Catarina Pelicano, Marina Costa, Sofia Mensurado, Natacha Gonçalves-Sousa, Pedro H. Papotto, Daniel Neves, Daniel Sobral, Francisco J. Enguita, Bruno Silva-Santos, Anita Q. Gomes

PLOS Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pbio.3003271

Small serine recombinases are markers for antiphage defense system discovery

Shelby E. Andersen, Joshua M. Kirsch, Navtej Singh, Stephen R. Garrett, John C. Whitney, Jay R. Hesselberth, Breck A. Duerkop

PLOS Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pbio.3003991

Heme acts as a metabolic brake on erebosis in the Drosophila gut

Motohiro Morikawa, Tetsutaro Hayashi, Yuko Ikegawa, Tomomi Takano, Kazuya Wata, Hirohisa Kyogoku, Mariko Kuse, Mika Yoshimura, Hiroshi Nishida, Rahul Parit, Dao My Linh, Kanta Kawai, Tasuku Hirayama, Chun Wang Sy, Kan Etoh, Itoshi Nikaido, Sa Kan Yoo

PLOS Biology: published August 19, 2026 | https://doi.org/10.1371/journal.pbio.3003942

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Editorial Note: Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells

The PLOS Biology Editors

PLOS Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pbio.3003875

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