Seaweed carbon removal cannot keep up with climate-driven loss

Karen Filbee-Dexter, Albert Pessarrodona, Kira A. Krumhansl, Thomas Wernberg

PLOS Biology: published September 8, 2026 | https://doi.org/10.1371/journal.pbio.3003949

Does acute inflammation triggered by infection promote cancer progression?

Felipe Valença-Pereira, Bryan Johnson, James DeGregori, Mercedes Rincon

PLOS Biology: published September 15, 2026 | https://doi.org/10.1371/journal.pbio.3003962

How the brain dances across critical boundaries

Audrey J. Sederberg

PLOS Biology: published September 2, 2026 | https://doi.org/10.1371/journal.pbio.3003950

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How the mosquito’s carbon dioxide sense gets an internal boost

Chih-Ying Su

PLOS Biology: published September 11, 2026 | https://doi.org/10.1371/journal.pbio.3003958

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A trade-off between fungal biofilm formation and persistence in the host

Shannon Esher Righi

PLOS Biology: published September 29, 2026 | https://doi.org/10.1371/journal.pbio.3004027

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Turning a phage anti-defense weapon into an immunity trigger

Anna B. Adelstein, Naama Aviram

PLOS Biology: published September 16, 2026 | https://doi.org/10.1371/journal.pbio.3003978

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Who Eats Whom? A global food web derived from citizen science

Bradley C. Allf, Aditi Mallavarapu, David W. Kikuchi, Nikhil Vasudeva, Robert R. Dunn

PLOS Biology: published September 22, 2026 | https://doi.org/10.1371/journal.pbio.3003988

The 100 Diatom Genomes Project

Thomas Mock, Gust Bilcke, Eliott Flaum, Shunan Fu, Lilian Hoch, Kevin Moog, Nadine Rijsdijk, Elizabeth C. Ruck, Ian W. Bishop, Carole Duchene, Reuben Gilbertson, Amanda Hopes, Christopher Johns, Francesco Manfellotto, Wade R. Roberts, Nigel Belshaw, Udita Chandola, Peter Chaerle, Olga Chepurnova, Daan Deleu, Sofie D’hondt, Federica Di Costanzo, Omaya Dudin, Serena Flori, Trupti Gaikwad, Agnes Groisillier, Andrea Hall, Pengyu Ji, Louis J. Lavier-Aydat, William H. Lewis, Samuel Menicot, Eveline Pinseel, Eléonore Pottier, Krisztina Sarkozi, Arianna Smerilli, Jan Strauss, Sander Thierens, Andrew Toseland, Yousef Touhami, Robert Utting, Michiel Van Bel, Cock van Oosterhout, Yue Wu, Feng Yang, Erika Allhusen, John J. Bolton, Chris Bowler, Thorsten Brinkhoff, Anja Poehlein, Tim Brovarone, Nansheng Chen, Greg Clark, Matthew D. Clark, Dario Copetti, Zongmei Cui, Beini Deng, Jianbo Jian, Uwe John, Anne D. Jungblut, JiHeon Kang, Jon Bent Kristoffersen, JunMo Lee, Shuya Liu, David G. Mann, Linda Medlin, Vincent Moulton, Jelena Radojicic, Shinya Sato, Rosa Trobajo, Klara Wolf, Norico Yamada, Naihao Ye, Libin Zhang, Yunyun Zhuang, Gautam Dey, Valeria Di Dato, Katherine Helliwell, Marianne Jaubert, Peter G. Kroth, Marina Montresor, Giovanna Romano, Tatiana A. Rynearson, Jayson Talag, Klaus U. Valentin, Flora Vincent, Ross F. Waller, Glen Wheeler, Andrew J. Alverson, Kerrie Barry, LoriBeth Boston, Angela Falciatore, Maria Immacolata Ferrante, Jie Guo, Jane Grimwood, Richard Hayes, Andrei Herdean, Jerry Jenkins, Min Kim, Wiebe HCF Kooistra, Alan Kuo, Anna Lipzen, Nicole Poulsen, Jeremy Schmutz, Leïla Tirichine, Klaas Vandepoele, Frédéric Verret, Wim Vyverman, Igor V. Grigoriev

PLOS Biology: published September 1, 2026 | https://doi.org/10.1371/journal.pbio.3003947

Gene flow drives periods of both evolutionary stasis and change in a wild bird population

Simon R. Evans, Henri Bouwmeester, Arie J. van Noordwijk, Marcel E. Visser, Erik Postma

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3004004

The distribution of fitness effects of nonsynonymous mutations varies phylogenetically across animals

Meixi Lin, Sneha Chakraborty, Carlos Eduardo G. Amorim, Sergio F. Nigenda-Morales, Annabel C. Beichman, Paulina G. Nuñez-Valencia, Jonathan C. Mah, Jacqueline A. Robinson, Christopher C. Kyriazis, Christian D. Huber, Andrew E. Webb, Sarah D. Kocher, Frederick I. Archer, Andrés Moreno-Estrada, Robert K. Wayne, Kirk E. Lohmueller

PLOS Biology: published September 8, 2026 | https://doi.org/10.1371/journal.pbio.3003976

Coordinated P450–UGT detoxification contributes to furanocoumarin tolerance associated with host plant range divergence in Helicoverpa

Huidong Wang, Yajie Kong, Xinyue Su, Yu Shi, Jianpeng Zhang, Yinjia Wang, Yajuan Xiao, Xing Geng, Jing Song, Yueru Ye, Kairan Zuo, Chris Bass, Shutang Zhou

PLOS Biology: published September 22, 2026 | https://doi.org/10.1371/journal.pbio.3004013

Outbreaks of fluconazole-resistant Candida parapsilosis are driven by low-biofilm-producing isolates that emerge under host selection

Farnaz Daneshnia, Deepika Gunasekaran, Sean Bergin, Lisa Lombardi, Austin M. Perry, Liuyang Cai, Louise A. Walker, Tibor Nemeth, Süleyha Hilmioglu-Polat, Letal I. Salzberg, Arefeh Ebadati, Tobias Köhler, Gabriel Braune, João N. de Almeida, Giuseppina Caggiano, Julianne V. Kus, Pegah Mosharaf Ghahfarokhy, Julieta Munoz, Daniel J. Floyd, Diego Fuentes-Palacios, Samuel M. Gonçalves, Relber A. Gonçales, Mostafa Salehi, Jigar V. Desai, Agostinho Carvalho, Shenglin Mei, Carol A. Munro, Alex Hopke, Toni Gabaldón, Attila Gacser, Oliver Kurzai, Geraldine Butler, David S. Perlin, Wenjie Fang, Clarissa J. Nobile, Michael K. Mansour, Amir Arastehfar

PLOS Biology: published September 1, 2026 | https://doi.org/10.1371/journal.pbio.3003973

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Brain structural and functional connectivity converge prenatally but diverge after birth

Ruoke Zhao, Mingyang Li, Yuqi Zhang, Ruike Chen, Chenglin Ning, Zhiyong Zhao, Zhihan Yan, Meihao Wang, Dan Wu

PLOS Biology: published September 9, 2026 | https://doi.org/10.1371/journal.pbio.3003927

Intrinsic timescale develops hierarchically from sensorimotor to association cortex in youth and stabilizes in adulthood

Golia Shafiei, Joëlle Bagautdinova, Valerie J. Sydnor, Dani S. Bassett, Deanna M. Barch, Matthew Cieslak, Yong Fan, Elizabeth Flook, Alexandre R. Franco, Gregory Kiar, Audrey C. Luo, Michael P. Milham, Linden Parkes, Taylor Salo, Leah H. Somerville, Tien T. Tong, Russell T. Shinohara, Theodore D. Satterthwaite

PLOS Biology: published September 29, 2026 | https://doi.org/10.1371/journal.pbio.3004037

Arousal-driven critical roaming reproduces human functional connectivity dynamics

Anagh Pathak, Demian Battaglia

PLOS Biology: published September 1, 2026 | https://doi.org/10.1371/journal.pbio.3003916

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Impaired midfrontal‑motor theta phase synchronization characterizes maladaptive motivational behavior in people with obsessive‑compulsive disorder

Yu Pang, Dongsheng Zhou, Ziwen Peng, Wanting Liu, Ruojie Huang, Carol A. Seger, Qi Chen

PLOS Biology: published September 1, 2026 | https://doi.org/10.1371/journal.pbio.3003979

Recurrent synapses between CO₂-sensitive olfactory sensory neurons enable robust CO₂ detection in Aedes aegypti mosquitoes

Jialu Bao, Wesley Alford, Avinash Khandelwal, Laurel Walsh, George Lantz, Santiago Poncio, Laia Serratosa Capdevila, Yervand Azatian, Brian DePasquale, David G. C. Hildebrand, Meg A. Younger, Wei-Chung Allen Lee

PLOS Biology: published September 10, 2026 | https://doi.org/10.1371/journal.pbio.3003959

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Growth-rate coordination across the width of a leaf preserves its flatness

Kate Harline, Brendan Lane, Maura J. Zimmermann, Antoine Fruleux, Gabriella Mosca, Sören Strauss, Nik Tavakolian, James W. Satterlee, Chun-Biu Li, Abhyudai Singh, Arezki Boudaoud, Richard S. Smith, Adrienne H. K. Roeder

PLOS Biology: published September 8, 2026 | https://doi.org/10.1371/journal.pbio.3003993

Whole-organ single-cell mapping defines growth dynamics and clonal organization in developing and adult zebrafish livers

Hsiao-Yuh Roan, Xuejiao Tian, Wei-Chen Chu, Chia-Ming Lee, Hsin Chen, Fiorency Santoso, Chung-Han Wang, Yu-Hsiu Liu, Uday Kumar, He-Yun Hsiao, Chiou-Hwa Yuh, Bi-Chang Chen, Chen-Hui Chen

PLOS Biology: published September 28, 2026 | https://doi.org/10.1371/journal.pbio.3004007

Regional signaling controls stem cell-mediated regeneration in an invertebrate chordate

Tal Gordon, Tom Levy, Chester Jiamu Yu, Benyamin Rosental, Lauren Lubeck, Lucia Manni, Irving L. Weissman, Ayelet Voskoboynik

PLOS Biology: published September 18, 2026 | https://doi.org/10.1371/journal.pbio.3004000

Intestinal lipid metabolism controls molecular and behavioral immunity through NHR-68 and gut–brain signaling in Caenorhabditis elegans

Jie Ren, Yu Sang, Young-Mo Kim, Ernesto S. Nakayasu, Alejandro Aballay

PLOS Biology: published September 29, 2026 | https://doi.org/10.1371/journal.pbio.3004026

Collagen I promotes cancer cell survival via amino acid import and mTORC1/S6 activation

Mona Nazemi, Bian Yanes, Eric Vancauwenberghe, Ifeoluwa Oyelade, Heather Walker, Elena Rainero

PLOS Biology: published September 18, 2026 | https://doi.org/10.1371/journal.pbio.3003555

Pathogen subversion of neuro-epidermal signaling impairs lysosomal function to disrupt collagen homeostasis in Caenorhabditis elegans

Qian Li, Yating Liu, Hanyi Chen, Weilie Xiao, Bin Qi

PLOS Biology: published September 22, 2026 | https://doi.org/10.1371/journal.pbio.3004016

The nematode Caenorhabditis elegans has a cationic amphiphilic drug (CAD) defense system

Levon Tokmakjian, Duhyun Han, Kateryna Sihuta, Aanchal Aggarwal, Somayeh Pirhadi, Yao Wang, Andrew R. Burns, Brittany Cooke, Siyue Ren, Marios Gavrielatos, Jiabao Liu, Henry M. Krause, Carolyn L. Cummins, Justin Nodwell, David R. Koes, Peter J. Roy

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3004006

Hyperglycemic stress aggravates diabetic retinopathy and nephropathy by promoting cilium disassembly via a deacetylation- and methylation-mediated regulatory mechanism

Jie Ran, Changfeng Wei, Yang Yang, Yufei Zhang, Guizhi Guo, Nan Ma, Long Yin, Hongjun Fan, Jingrui Li, Heng Guo, Renshuai Zhang, Runa Wang, Dengwen Li, Min Liu

PLOS Biology: published September 3, 2026 | https://doi.org/10.1371/journal.pbio.3003975

Atlastin-2-mediated endoplasmic reticulum membrane tethering is critical for flavivirus replication

Jonathan Einterz Owen, Cheyanne Lynn Bemis, Qingyi Wang, Ambarish C. Varadan, Jacob W. Vander Velden, Laura Andačić, Olus Uyar, Mansi Gupta, Christopher D. Scharer, Laurent Chatel-Chaix, Pietro Scaturro, Mehul S. Suthar, Christopher J. Neufeldt

PLOS Biology: published September 15, 2026 | https://doi.org/10.1371/journal.pbio.3003556

The kinetoplastid-specific transcription factor mtTF1 is essential for mitochondrial gene expression and maxicircle replication in Trypanosoma brucei

Bianca Manuela Berger, Enrico Santini, Himaja Manjunatha, Lea Trost, Markus Gerber, Hauke S. Hillen, Torsten Ochsenreiter

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3003945

The carbohydrate utilization regulator Cbr1 coordinates nutrient-specific gene activation with selective carbon catabolite repression in a basidiomycete yeast

Brandon Reyes-Chavez, Joshua D. Kerkaert, Lori B. Huberman

PLOS Biology: published September 1, 2026 | https://doi.org/10.1371/journal.pbio.3003983

Cyclic tri-adenylate controls a CARF-TM effector in type II Panoptes anti-phage systems

Sabine Grüschow, Peter Wotherspoon, Emma Hilton-Balfe, Shirley Graham, Malcolm F. White

PLOS Biology: published September 15, 2026 | https://doi.org/10.1371/journal.pbio.3003934

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Epistasis and pleiotropy constrain the evolution of cross-reactive breadth in a broadly neutralizing influenza antibody

Katrine E. Dailey, Yiquan Wang, Qi Wen Teo, Chaoyang Wang, Huibin Lv, Ruipeng Lei, Meixuan Tong, Lucia A. Rodriguez, Letianchu Wang, Nicholas C. Wu

PLOS Biology: published September 28, 2026 | https://doi.org/10.1371/journal.pbio.3004021

R1-32-like public antibodies acquire tolerance to SARS-CoV-2 antigenic drift through somatic hypermutation

Chuanying Niu, Xiaohan Huang, Qihong Yan, Banghui Liu, Xijie Gao, Yidong Song, Jingjing Wang, Longyu Wang, Zimu Li, Huiran Zheng, Ping He, Xiaodong Huang, Hang Yuan, Binqian Zou, Yuedong Yang, Fandi Wu, Yicheng Yao, Gul Habib, Xinwen Chen, Ling Chen, Jun He, Jianhua Yao, Jincun Zhao, Xiaoli Xiong

PLOS Biology: published September 15, 2026 | https://doi.org/10.1371/journal.pbio.3003996

Antibodies targeting phage fiber and nozzle proteins impair Acinetobacter baumannii phage therapy by blocking infection and promoting immune clearance

Heng Xue, Xinfeng Li, Guibo Rao, Fen Hu, Mingyue Zhong, Paulina Miernikiewicz, Rui Qiu, Sheng Cao, Krystyna Dąbrowska, Hang Yang

PLOS Biology: published September 22, 2026 | https://doi.org/10.1371/journal.pbio.3004009

Monovalent cations differentially regulate the activity of eukaryotic fluoride channels and impact fluoride resistance

Chia-Yu Kang, Sahar Heidari, Sabrina Kolb, Minjun An, Melanie D. Ohi, Hedieh Torabifard, Randy B. Stockbridge

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3004008

Ancient inversion polymorphisms associate with sexually selected traits across natural guppy populations

Yuying Lin, Wouter van der Bijl, Judith E. Mank

PLOS Biology: published September 23, 2026 | https://doi.org/10.1371/journal.pbio.3004024

Adaptive introgression between two Drosophila species enhances heat tolerance despite barriers to gene flow

Noora Poikela, Rhonda R. Snook, Jonna Kulmuni, Michael G. Ritchie

PLOS Biology: published September 30, 2026 | https://doi.org/10.1371/journal.pbio.3004028

Nightjars trade off cruising speed efficiency for hovering capabilities and link upstroke thrust production with restricted wing folding

L. Christoffer Johansson, Gabriel Norevik, Sonja Friman, Anders Hedenström

PLOS Biology: published September 30, 2026 | https://doi.org/10.1371/journal.pbio.3004023

No evidence for modulation of the readiness potential by respiratory phase during natural breathing

Lucas Jeay-Bizot, Raniyah Chishti, Uri Maoz, Aaron Schurger

PLOS Biology: published September 2, 2026 | https://doi.org/10.1371/journal.pbio.3003982

Regeneration programs buffer genetic defects in animal development

Kazunori Ando, Sushant Bangru, John Welsby, John D. Thompson, Kenneth D. Poss

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3004011

Myelin sheath lengths in the central nervous system scale to axon diameter via oligodendroglial Piezo1

Amanda R. Young, Ashley Galfano, Jacob Reyngoudt, Ryan W. Lewis, Martha Cash, Beckam Polis, Myah Zalusky, Avipsha Datta, Marie E. Bechler

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3003992

MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosa

Yujun Jiang, Xin-Fu Yan, Rya Ero, Chao Wang, Kanaga Sabapathy, Yong-Gui Gao

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3003985

A developmental single-cell atlas of the Drosophila visual system glia reveals cell type diversification and subcellular mRNA compartmentalization

Amanda A. G. Ferreira, Sergio Córdoba, Raghuvanshi Rajesh, Ben Jiwon Choi, Claude Desplan

PLOS Biology: published September 28, 2026 | https://doi.org/10.1371/journal.pbio.3004015

SpaMOAL is a deep learning method that enables accurate spatial domain identification from multi-omics data

Jinxia Wang, Yuying Huo, Rui Zhao, Yan Pan, Jianqiang Wu, Han Wang, Xiangyu Li

PLOS Biology: published September 16, 2026 | https://doi.org/10.1371/journal.pbio.3003690

AlloPool is a deep learning framework that infers protein allostery from molecular dynamics simulations

Matthieu Marfoglia, Miguel A. Pedraza-Joya, Lucas Guirardel, Aisima Chatzi Souleiman, Patrick Barth

PLOS Biology: published September 21, 2026 | https://doi.org/10.1371/journal.pbio.3004002

Discovery Stack Pilot demonstrates the feasibility and outcomes of a scientist-designed peer-review model that separates quality and impact

Maureen A. McGargill, Beiyun C. Liu, Michael S. Kuhns, Daniel Mucida, Isabella Rauch, Lauren B. Rodda, Meghan A. Koch, Hugo Gonzalez Velozo, Ken Cadwell, Tanya S. Freedman, Tiffany C. Scharschmidt, Richard Sever, Jose Ordovas-Montanes, Sara Suliman, Andrew Oberst, Brooke Runnette, Matthew F. Krummel

PLOS Biology: published September 8, 2026 | https://doi.org/10.1371/journal.pbio.3003986

An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut

Audam Chhun, Andrew Quinn, Alicia I. Pérez-Lorente, Théodora Steiner, Florian Zoppi, Thi Huong Giang Nguyen, Philipp Engel, Yolanda Schaerli

PLOS Biology: published September 16, 2026 | https://doi.org/10.1371/journal.pbio.3003997

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