De novo assembly and authentication of ancient DNA metagenomes with nf-core/mag

James A. Fellows Yates, Alexander Hübner, Maxime Borry, nf-core community, Christina Warinner

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014591

Twelve quick tips for applying deep learning to animal sounds

Burooj Ghani, Anne Leonie Baier, Vincent J. Kalkman, Dan Stowell

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014604

Ten simple rules for effective use of generative AI for code development in environmental science

Rachel A. King, Laurel Abowd, Carlo W. Broderick, LM Bradley, Max F. Czapanskiy, Mona M. Farnisa, Erica M. Ferrer, Carmen Galaz García, Darian Gill, Nicole M. Greco, Juliette Jacquemont, Justin A. Kadi, Li Kui, Gretchen LeBuhn, Liying Li, Abigail Meyer, Marisa Morse, Evan Patrick, Samantha Shanny-Csik, Nicholas A. C. Tucker, Zhe Wang, Caitlin R. Fong

PLOS Computational Biology: published August 17, 2026 | https://doi.org/10.1371/journal.pcbi.1014627

Ten quick tips for causal analysis of biomedical omics data

Gleb Svinin, Rebecca Ting Jiin Loo, Nikhilesh Vasantha Kumar, Varsha Venkatesha Murthy, Dilara Uzuner Odongo, Ramón Díaz-Uriarte, Ana Conesa, Gianluca Bontempi, Susana Vinga, Ilaria Granata, Daniel Domingo-Fernández, Paola Lecca, Marieke L. Kuijjer, Jesse H. Krijthe, Ina Koch, Laurence Calzone, Simona Ester Rombo, Fátima Sánchez-Cabo, Enrico Glaab

PLOS Computational Biology: published August 20, 2026 | https://doi.org/10.1371/journal.pcbi.1014668

Eleven quick tips for Biomedical Federated Learning

Kyle Ellrott, Venkat S. Malladi, Jean-Christophe Bélisle-Pipon, Emek Demir, Yael Bensoussan, Serghei Mangul, Alex A. T. Bui, Paul C. Boutros

PLOS Computational Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pcbi.1014530

The multi-omics fallacy in microbiome science

Rebecca Lewandowski

PLOS Computational Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pcbi.1014700

Model Context Protocol: The unexpected catalyst of a bioinformatics interoperability revolution

Nathan C. Sheffield

PLOS Computational Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pcbi.1014543

Successful reinforcement history suppresses explicit and implicit error corrections

John Buggeln, Nicholas Muscara, Seth R. Sullivan, Jan A. Calalo, Truc T. Ngo, Matthew Short, Adam M. Roth, Michael J. Carter, Joshua G. A. Cashaback

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014574

Accurate de novo transcription unit annotation from run-on and sequencing data

Paul R. Munn, Jay Chia, Charles G. Danko

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014559

Cell-specific Cahn-Hilliard models predict condensed fates of the chromosomal passenger complex

Sarah M. Groves, Min-Jhe Lu, Astrid Catalina Alvarez-Yela, Monserrat Gerardo-Ramírez, P. Todd Stukenberg, John S. Lowengrub, Kevin A. Janes

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014568

Impact of insecticide resistance evolution on malaria vector control

Neil Philip Hobbs, Sumin Kim, Thiery Masserey, Nakul Chitnis

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014612

Accounting for the long-distance transmission route: An epidemiological model of airborne disease transmission in hospitals

Olivier Gaufrès, Quentin J. Leclerc, Julien Derdevet, George Shirreff, Solen Kernéis, Lulla Opatowski, Laura Temime, Maylis Layan

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014564

Deep learning-supported image quantification of epithelial cell shapes and its application to polycystic kidney disease

Johannes Jahn, Alexis Hofherr, Clara Consoli, Berenike Fajen, Rebekka Goll, Greta Theresa Liedtke, Adrian Boehm, Friederike Selbach, Paul Christoph Zeisler, Vanessa Weichselberger, Anne-Kathrin Classen, Lukas Westermann, Tilman Busch, Michael Köttgen

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014614

A synthetic 3D human cerebrovascular model informed by histology for simulating the cortical depth-dependent BOLD fMRI signal

Mario Gilberto Báez-Yáñez, Jeroen C. W. Siero, Matthias J. P. van Osch, Natalia Petridou

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014576

Closed-loop real-virtual interactions validate 3D model of social coordination in fish

Ramón Escobedo, Justine Reynaud, Renaud Bastien, Stéphane Sanchez, Clément Sire, Guy Theraulaz

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014544

Assessing the validity and reliability of computational phenotyping of mood

Pablo Carrillo, Marc Benhamou, Roeland Heerema, Jean Daunizeau, Mathias Pessiglione, Fabien Vinckier

PLOS Computational Biology: published August 3, 2026 | https://doi.org/10.1371/journal.pcbi.1014597

A fast numerical integration scheme for clonal expansion processes on graphs

Chay Paterson, Miaomiao Gao, Joshua Hellier, Georg Luebeck, David C. Wedge, Ivana Bozic

PLOS Computational Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pcbi.1012784

Quantifying the impact of vaccination on pertussis dynamics in Sweden

Tobias S. Brett, Andrew Tredennick, Michael Briga, Laurent Coudeville, Denis Macina, Matthieu Domenech de Cellès, Pejman Rohani

PLOS Computational Biology: published August 4, 2026 | https://doi.org/10.1371/journal.pcbi.1014538

Motif-Cluster: Motif driven prioritization of transcription factor binding clusters

Mengyuan Zhou, Qiuming Yao

PLOS Computational Biology: published August 5, 2026 | https://doi.org/10.1371/journal.pcbi.1014639

AddaGCN: Spatial transcriptomics deconvolution using graph convolutional networks with adversarial discriminative domain adaptation

Shuzhen Ding, Zhou Yu, Jingsi Ming

PLOS Computational Biology: published August 5, 2026 | https://doi.org/10.1371/journal.pcbi.1014609

Stochastic modeling of long-legged ant A. gracilipes locomotion in laboratory experiments

Jack Featherstone, Anouk Béraud, Meta Virant-Doberlet, Antonio Celani, Mahesh M. Bandi

PLOS Computational Biology: published August 6, 2026 | https://doi.org/10.1371/journal.pcbi.1014069

Neural population models for EEG: From Canonical models to alternative model structures

Nina Omejc, Sabin Roman, Ljupčo Todorovski, Sašo Džeroski

PLOS Computational Biology: published August 6, 2026 | https://doi.org/10.1371/journal.pcbi.1014222

Decoding behavior with minimal and interpretable agent models

Giorgio Nicoletti, Antonio Celani

PLOS Computational Biology: published August 7, 2026 | https://doi.org/10.1371/journal.pcbi.1014585

Toward reliable machine learning models for neural circuit inference: A diagnostic study of CNNs on spike trains

Xiaoqian Sun, Hui Lu, Chen Zeng, Rahul Simha

PLOS Computational Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pcbi.1014615

An alignment-free strategy for circulating tumor DNA detection and tumor fraction estimation from whole-genome sequencing data

Carmen Oroperv, Amanda Frydendahl, Tenna Vesterman Henriksen, Giovanni Santacatterina, Alice Antonello, Nicola Calonaci, Mads Heilskov Rasmussen, Giulio Caravagna, Claus Lindbjerg Andersen, Søren Besenbacher, IMPROVE-consortia

PLOS Computational Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pcbi.1013356

SKIM: A fast sketching strategy integrated with model’s dynamic-feedback for large-scale single-cell transcriptomic analysis

Jiaxing Bai, Feng Zhou, Chongyang Tan, Yichun Gao, Yushuang He, Xiaobing Huang, Ying Wang

PLOS Computational Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pcbi.1014638

RareCapsNet: An explainable capsule network enables robust discovery of rare cell populations from large-scale single-cell transcriptomics

Sumanta Ray, Snehalika Lall

PLOS Computational Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pcbi.1013962

EvoSNR-Prom: Predicting promoters at single-nucleotide resolution with label-aware transfer learning of the pretrained EVO model

Pi-Jing Wei, Wenkang Zheng, Yijun Gu, Chun-Hou Zheng

PLOS Computational Biology: published August 10, 2026 | https://doi.org/10.1371/journal.pcbi.1014626

CRITERIA: A network decomposition and elementary flux mode translation-based tool for computing equilibria of biochemical systems

Exequiel Jun V. Villejo, Aurelio A. de los Reyes V, Bryan S. Hernandez

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014633

Edge-aware GAT-based protein binding sites prediction

Weisen Yang, Hanqing Zhang, Wangren Qiu, Xuan Xiao, Weizhong Lin

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014552

The genetic code at the balance point of error and demand

Yudam Seo, Tsvi Tlusty, Junghyo Jo

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014613

Alignment-free prediction of cross-reactivity in influenza A (H3N2) anticipates antigenic drift

Alpha Forna, Lambodhar Damodaran, Christian E. Gunning, Parnian Rahimi, Aarya Venkat, Natarajan Kannan, Rebecca Kondor, Justin Bahl, Pejman Rohani, John M. Drake

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014628

Assessing the reliability of cellular decision making from noisy, multidimensional single-cell TNF–NF-κB signaling data

Ali Emadi, Tomasz Lipniacki, Andre Levchenko, Ali Abdi

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014608

REvolutionH-tl 2.0: A fast and robust tool for decoding evolutionary gene histories

José Antonio Ramírez-Rafael, Annachiara Korchmaros, Katia Aviña-Padilla, Alitzel López-Sánchez, Gabriel Martinez-Medina, Alfredo J. Hernández-Álvarez, Marc Hellmuth, Peter F. Stadler, Maribel Hernández-Rosales

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1013017

A benchmarking study of feature screening approaches across type 1 diabetes omics studies classification settings

Erik D. VonKaenel, Lisa M. Bramer, Javier E. Flores, Thomas O. Metz, Ernesto S. Nakayasu, Bobbie-Jo M. Webb-Robertson

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014625

An agent-based model of Trypanosoma brucei social motility to explore determinants of colony pattern formation

Andreas Kuhn, Timothy Krüger, Markus Engstler, Sabine C. Fischer

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1013698

Evaluation of short-term multi-target respiratory forecasts over winter 2024-25 in England using sub-ensemble contribution analyses

Jack Kennedy, William Ferguson, Owen Jones, Steven Riley, Thomas Ward, Maria L. Tang, Jonathon Mellor

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014644

Mechanical power output during stretch–shortening cycles of rat medial gastrocnemius muscle: Influence of various muscle length trajectories

Edwin D. H. M. Reuvers, Huub Maas, Wendy Noort, Maarten F. Bobbert, Dinant A. Kistemaker

PLOS Computational Biology: published August 12, 2026 | https://doi.org/10.1371/journal.pcbi.1014587

Improving the reliability of polygenic risk score-based prediction for cardiovascular and renal complications across ancestries in type 2 diabetes using Mondrian Cross-Conformal Prediction

Edoh Kodji, Redha Attaoua, Mounsif Haloui, Camil Hishmih, Mirjam Seitz, Mark Woodward, Julie G. Hussin, Pavel Hamet, Johanne Tremblay

PLOS Computational Biology: published August 13, 2026 | https://doi.org/10.1371/journal.pcbi.1014670

scKanFormer: A Transformer-KAN framework with biologically informed attention for cell type annotation in large-scale scRNA-seq data

Lin Yuan, Junjie Cao, Shengguo Sun, Siguo Wang, Lan Ye, De-Shuang Huang

PLOS Computational Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pcbi.1014607

CLASPP: A unified model for predicting post-translational modifications

Nathan Gravel, Zhongliang Zhou, Ruili Fang, Austin Downes, Saber Soleymani, Natarajan Kannan

PLOS Computational Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pcbi.1014616

Design of an immunogen containing multidimensionally conserved and immunogenic parts of the HIV proteome

Eric Wang, Arup K. Chakraborty

PLOS Computational Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pcbi.1014632

Structure-aware deep learning enhances m6A prediction and reveals cell type-associated RNA structural signatures

Mingze Sun, Di Zhang, Zhiyuan Li, Yihan Lin

PLOS Computational Biology: published August 14, 2026 | https://doi.org/10.1371/journal.pcbi.1014649

Contrastive learning to fine-tune feature extraction models for the visual cortex

Alex Mulrooney, Zhi Li, Austin J. Brockmeier

PLOS Computational Biology: published August 17, 2026 | https://doi.org/10.1371/journal.pcbi.1014656

The limitations of non-mechanistic methods for characterizing pathogen-pathogen interactions: A simulation study

Sarah C. Kramer, Sarah Pirikahu, Cana Kussmaul, Lulla Opatowski, Matthieu Domenech de Cellès

PLOS Computational Biology: published August 17, 2026 | https://doi.org/10.1371/journal.pcbi.1013859

Reconciling contradictory models of subthalamic nucleus contributions to basal ganglia beta oscillations

Ka Nap Tse, G. Bard Ermentrout, Jonathan E. Rubin

PLOS Computational Biology: published August 17, 2026 | https://doi.org/10.1371/journal.pcbi.1013942

IBAS: Interaction-bridged association studies discovering novel genes underlying complex traits

Dinghao Wang, Pathum Kossinna, Karen Ardila, Senitha Kumarapeli, M. Ethan MacDonald, Jingjing Wu, Qingrun Zhang

PLOS Computational Biology: published August 17, 2026 | https://doi.org/10.1371/journal.pcbi.1014640

ERFMTDA: Predicting tsRNA–disease associations using an enhanced rotative factorization machine

Wei Lan, Dong Wang, Wenyi Chen, Xuhua Yan, Qingfeng Chen, Shirui Pan, Yi Pan

PLOS Computational Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pcbi.1014594

The SATvac model of CD8⁺ T cell expansion and contraction phases considering memory and effector cell differentiation

Seyedeh Fatemeh Seyyedizadeh, David A. Christian, Thomas A. Adams II

PLOS Computational Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pcbi.1014702

Cerebellum-inspired neural network of supervised learning with tensor-based sparse coding for multi-class classification

Runguang Zhou, Douglas Zhou, Songting Li, Xiaoyu Chen

PLOS Computational Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pcbi.1014595

Reassessing adult surfactant replacement therapy with mechanics-informed reinforcement learning

Philippe Meliga, Gregor Roncin, Alejandro Yepes Peñaranda, Elie Hachem

PLOS Computational Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pcbi.1014629

Can intrinsic loop energetics predict G-Quadruplex topology?

Michał Jurkowski, Mateusz Kogut, Mikołaj Ławicki, Jacek Czub

PLOS Computational Biology: published August 18, 2026 | https://doi.org/10.1371/journal.pcbi.1014542

Enzyme kinetics shapes the growth response of metabolic networks

Leon Seeger, Fernanda Pinheiro, Michael Lässig

PLOS Computational Biology: published August 19, 2026 | https://doi.org/10.1371/journal.pcbi.1014642

CLDN18.2 antibody design with protein language models: A deep learning optimization framework

Tao Qu, Lingyan Yuan, Weiran Cui, Jiatian Tang, Zhitong Bing, Xianghong Xu, Jizheng Duan, Qiong Yang, Hui Cai

PLOS Computational Biology: published August 20, 2026 | https://doi.org/10.1371/journal.pcbi.1014499

A portable recalibration workflow for reference-based variant calling in non-human genomes

Hyeonjung Lee, Sunhee Kim, Michelle Audrelia Sunartha, Chang-Yong Lee, Young-suk Lee

PLOS Computational Biology: published August 20, 2026 | https://doi.org/10.1371/journal.pcbi.1014603

Non-Markovian dynamics and effective reproduction number in COVID-19: Evidence from Cyprus contact tracing data

Pavlos Alexandros Dimitriou, Matteo D’Alessandro, Brian L. Chang, Valentinos Silvestros, Elisavet Constantinou, Costas Pitris, Panayiotis Kolios, Piet Van Mieghem

PLOS Computational Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pcbi.1014578

An in silico framework for dissecting the mechanistic origins of in vivo recorded neuronal activity

Bjorge Meulemeester, Arco Bast, María Royo, Rieke Fruengel, Su Saka, Foivos Kastrinakis, Marcel Oberlaender

PLOS Computational Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pcbi.1014617

The perils of omitting omissions when modeling evidence accumulation

Xiamin Leng, Alexander Fengler, Amitai Shenhav, Michael J. Frank

PLOS Computational Biology: published August 21, 2026 | https://doi.org/10.1371/journal.pcbi.1014667

How host mobility formulations shape estimates of pathogen dispersal and epidemic risk in non endemic regions

Charley Presigny, Piero Poletti, Stefano Merler, Manlio De Domenico

PLOS Computational Biology: published August 24, 2026 | https://doi.org/10.1371/journal.pcbi.1014646

Mechanochemical modeling of exercise-induced skeletal muscle hypertrophy

Ingvild S. Devold, Marie E. Rognes, Padmini Rangamani

PLOS Computational Biology: published August 24, 2026 | https://doi.org/10.1371/journal.pcbi.1014691

Double shrinkage transfer causal learning: An application to alzheimer’s disease

Yunxin Shi, Lulu Pan, Yu Hu, Yongfu Yu, Guoyou Qin

PLOS Computational Biology: published August 24, 2026 | https://doi.org/10.1371/journal.pcbi.1014706

Theory and evidence of amplitude control by frequency detuning in a coupled neuronal oscillator system

Adam C. Lu, Seyed AmirHossein Ourang, Jeffrey D. Moore

PLOS Computational Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pcbi.1014686

Manifold-constrained plasticity enables stable learning in recurrent neural circuits

Camille Godin, Jean-Philippe Thivierge

PLOS Computational Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pcbi.1014719

High reelin expression may explain why a subgroup of entorhinal cortex neurons functions as an initial nucleation site of Alzheimer’s disease

Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt

PLOS Computational Biology: published August 25, 2026 | https://doi.org/10.1371/journal.pcbi.1014532

Modeling the influences of non-local connectomic projections on geometrically constrained cortical dynamics

Rishikesan Maran, Eli J. Müller, Ben D. Fulcher

PLOS Computational Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pcbi.1014673

Multiscale modeling of T cell exhaustion: A mathematical framework integrating continuous dynamics with spatial heterogeneity

Chenghang Li, Yuhong Zhang, Xue Liu, Yipu Qu, Xiulan Lai, Jinzhi Lei

PLOS Computational Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pcbi.1014690

Simulation and inference methods for non-Markovian stochastic reaction networks

Thomas P. Steele, David J. Warne

PLOS Computational Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pcbi.1014687

The complex swarming dynamics of malaria mosquitoes emerge from simple minimally-interactive behavioral rules

Antoine Cribellier, Bèwadéyir Serge Poda, Roch K. Dabiré, Abdoulaye Diabaté, Olivier Roux, Florian T. Muijres

PLOS Computational Biology: published August 26, 2026 | https://doi.org/10.1371/journal.pcbi.1014685

iDCF: Interpretable deconvolution of cell fractions via biologically-informed deep learning using scRNA-seq data

Hongjiang Guo, Tingfang Wu, Wenzheng Wang, Yelu Jiang, Geng Li, Liangpeng Nie, Yunhua Jia, Lijun Quan, Moli Huang, Qiang Lyu

PLOS Computational Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pcbi.1014727

Leveraging synthetic and genetic data to improve epidemic forecasting

Dave Osthus, Alexander C. Murph, Emma E. Goldberg, Lauren J. Beesley, William M. Fischer, Nidhi Parikh, Lauren A. Castro

PLOS Computational Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pcbi.1014630

Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenetic vulnerability

Luisa Quesada Camacho, Mohammad Fallahi-Sichani

PLOS Computational Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pcbi.1014018

Noisy models of the ventral stream reveal the impact of recurrence and learned representations on information processing timescales

Sara Varetti, Sebastian Goldt, Eugenio Piasini

PLOS Computational Biology: published August 27, 2026 | https://doi.org/10.1371/journal.pcbi.1014653

ASPIRE: Accurate alternative splicing prediction from limited RNA sequencing data and a minimal gene set

Ran Eisenberg, Efraim Rahamim, Eli Kopel, Miri Danan-Gotthold, Erez Y. Levanon, Ofir Lindenbaum

PLOS Computational Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pcbi.1014725

Metal binding site alignment enables network-driven discovery of recurrent geometries across sequence-divergent proteins and drug off-targets

Vetle Simensen, Eivind Almaas

PLOS Computational Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pcbi.1014636

Disentangling the drivers of heterogeneity in SARS-CoV-2 transmission from data on viral load and daily contact rates

Billy J. Quilty, Lloyd A. C. Chapman, James D. Munday, Kerry L. M. Wong, Amy Gimma, Suzanne Pickering, Stuart Neil, Rui Pedro Galao, W. John Edmunds, Christopher I. Jarvis, Adam J. Kucharski

PLOS Computational Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pcbi.1014715

GPCR-GO: Relation-aware graph learning for predicting Gene Ontology terms of G protein-coupled receptors

Anchi Sun, Yongjing Hao, Yijie Ding, Jing Chen, Hongjie Wu

PLOS Computational Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pcbi.1014718

Simple birth-death-mutation models predict some—but not all—aspects of the experimental evolution of antibiotic resistance

Elin Lilja, Rosalind J. Allen, Bartlomiej Waclaw

PLOS Computational Biology: published August 28, 2026 | https://doi.org/10.1371/journal.pcbi.1014666

Economic factors promoting vaccine nationalism in the face of viral evolution

Ari S. Freedman, Bjarke Frost Nielsen, Chadi M. Saad-Roy, Bryan T. Grenfell, C. Jessica E. Metcalf, Simon A. Levin

PLOS Computational Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pcbi.1014466

Prospects of HIV elimination among men who have sex with men: A systematic review of modeling studies

Jacob Aiden Roberts, Alexandra Teslya, Mirjam E. Kretzschmar, Janneke H.H.M. van de Wijgert, Ganna Rozhnova

PLOS Computational Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pcbi.1014596

Mapping spatial colleague connectivity patterns from individual-level registry data to inform regional pandemic interventions

PingPing Song, Sake J. de Vlas, Tom Emery, Luc E. Coffeng

PLOS Computational Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pcbi.1014721

Population morphology implies a common developmental blueprint for Drosophila motion detectors

Nikolas Drummond, Arthur Zhao, Alexander Borst

PLOS Computational Biology: published August 31, 2026 | https://doi.org/10.1371/journal.pcbi.1014657

Correction: Predictive modeling of gene expression and localization of DNA binding site using deep convolutional neural networks

Arman Karshenas, Tom Röschinger, Hernan G. Garcia

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014647

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Correction: Training biologists in Unix command-line skills: From curriculum to interactive online tutorials

Lucie Khamvongsa-Charbonnier, Robert Aboukhalil, Hélène Chiapello, Thomas Denecker, Pierre Poulain, Denis Puthier, Olivier Sand, Morgane Thomas-Chollier, Claire Toffano-Nioche

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Real-time GPU-accelerated coupled cardiac system: Integrating bidirectional interactions between living optogenetic monolayers and computational simulations

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ScanNet: Single-cell annotation informed by transcriptional regulation Network via iterative heterogeneous graph learning

Yongyu Long, Wenhao Zhang, Lan Cao, Xiaobing Huang, Ying Wang

PLOS Computational Biology: published August 6, 2026 | https://doi.org/10.1371/journal.pcbi.1014602

Collective posterior inference from highly variable empirical replicates

Nadav Ben Nun, Saharon Rosset, David Gresham, Yoav Ram

PLOS Computational Biology: published August 11, 2026 | https://doi.org/10.1371/journal.pcbi.1014534

GeneInsight: Condensing gene set knowledge via language models

Wee Loong Chin, Kevin Chen, Timo Lassmann

PLOS Computational Biology: published August 5, 2026 | https://doi.org/10.1371/journal.pcbi.1014500