The scarce swallowtails Iphiclides feisthamelii and Iphiclides podalirius meet at a contact zone north of the Pyrenees. Ebdon et al. capture their speciation dynamics by contrasting patterns of gene flow acting on different time scales. They show that these papilionid butterflies continue to hybridise after over a million years, and there is concordance in barriers to gene flow acting across recent and deep time. See Ebdon et al.
Image Credit: Roger Vila
Research Articles
A Rfa1-MN–based system reveals new factors involved in the rescue of broken replication forks
PLOS Genetics: published April 1, 2025 | https://doi.org/10.1371/journal.pgen.1011405
Identification of modifier gene variants overrepresented in familial hypomagnesemia with hypercalciuria and nephrocalcinosis patients with a more aggressive renal phenotype
PLOS Genetics: published April 2, 2025 | https://doi.org/10.1371/journal.pgen.1011568
A phage-encoded counter-defense inhibits an NAD-degrading anti-phage defense system
PLOS Genetics: published April 2, 2025 | https://doi.org/10.1371/journal.pgen.1011551
ClpP2 proteasomes and SpxA1 determine Listeria monocytogenes tartrolon B hyper-resistance
PLOS Genetics: published April 4, 2025 | https://doi.org/10.1371/journal.pgen.1011621
Spindle integrity is regulated by a phospho-dependent interaction between the Ndc80 and Dam1 kinetochore complexes
PLOS Genetics: published April 4, 2025 | https://doi.org/10.1371/journal.pgen.1011645
Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans
PLOS Genetics: published April 7, 2025 | https://doi.org/10.1371/journal.pgen.1011444
PPDPF is not a key regulator of human pancreas development
PLOS Genetics: published April 7, 2025 | https://doi.org/10.1371/journal.pgen.1011657
Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways
PLOS Genetics: published April 9, 2025 | https://doi.org/10.1371/journal.pgen.1011407
Probabilistic classification of gene-by-treatment interactions on molecular count phenotypes
PLOS Genetics: published April 9, 2025 | https://doi.org/10.1371/journal.pgen.1011561
Condensin IDC, DPY-21, and CEC-4 maintain X chromosome repression in C. elegans
PLOS Genetics: published April 9, 2025 | https://doi.org/10.1371/journal.pgen.1011247
Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector
PLOS Genetics: published April 9, 2025 | https://doi.org/10.1371/journal.pgen.1011653
The identification of blood-derived response eQTLs reveals complex effects of regulatory variants on inflammatory and infectious disease risk
PLOS Genetics: published April 10, 2025 | https://doi.org/10.1371/journal.pgen.1011599
Enhancing nonlinear transcriptome- and proteome-wide association studies via trait imputation with applications to Alzheimer’s disease
PLOS Genetics: published April 10, 2025 | https://doi.org/10.1371/journal.pgen.1011659
Genomic regions of current low hybridisation mark long-term barriers to gene flow in scarce swallowtail butterflies
PLOS Genetics: published April 10, 2025 | https://doi.org/10.1371/journal.pgen.1011655
Exploring the molecular basis of the genetic correlation between body mass index and brain morphological traits
PLOS Genetics: published April 10, 2025 | https://doi.org/10.1371/journal.pgen.1011658
Deep-time gene expression shift reveals an ancient change in avian muscle phenotypes
PLOS Genetics: published April 11, 2025 | https://doi.org/10.1371/journal.pgen.1011663
YebC2 resolves ribosome stalling and increases fitness of cells lacking EF-P and the ABCF ATPase YfmR
PLOS Genetics: published April 11, 2025 | https://doi.org/10.1371/journal.pgen.1011633
Identification of quantitative trait loci (QTLs) for key cheese making phenotypes in the blue-cheese mold Penicillium roqueforti
PLOS Genetics: published April 15, 2025 | https://doi.org/10.1371/journal.pgen.1011669
Myelin regulatory factor (MYRF) is a critical early regulator of retinal pigment epithelial development
PLOS Genetics: published April 15, 2025 | https://doi.org/10.1371/journal.pgen.1011670
Germline mutation rates and fine-scale recombination parameters in zebra finch
PLOS Genetics: published April 15, 2025 | https://doi.org/10.1371/journal.pgen.1011661
Mammary gland multi-omics data reveals new genetic insights into milk production traits in dairy cattle
PLOS Genetics: published April 17, 2025 | https://doi.org/10.1371/journal.pgen.1011675
Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity
PLOS Genetics: published April 25, 2025 | https://doi.org/10.1371/journal.pgen.1011678
Meiotic divisions and round spermatid formation do not require centriole duplication in mice
PLOS Genetics: published April 28, 2025 | https://doi.org/10.1371/journal.pgen.1011698
Disentangling the mutational effects on protein stability and interaction of human MLH1
PLOS Genetics: published April 28, 2025 | https://doi.org/10.1371/journal.pgen.1011681
In vivo AGO-APP identifies a module of microRNAs cooperatively preserving neural progenitors
PLOS Genetics: published April 29, 2025 | https://doi.org/10.1371/journal.pgen.1011680
Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci
PLOS Genetics: published April 30, 2025 | https://doi.org/10.1371/journal.pgen.1011446
Heat inducible nuclear translocation of Kdm6bb drives temperature dependent sex reversal in Nile tilapia
PLOS Genetics: published April 30, 2025 | https://doi.org/10.1371/journal.pgen.1011664
Correction
Correction: Histone variant H2A.Z is needed for efficient transcription-coupled NER and genome integrity in UV challenged yeast cells
PLOS Genetics: published April 1, 2025 | https://doi.org/10.1371/journal.pgen.1011646
Related Articles
Methods
Isolating selective from non-selective forces using site frequency ratios
PLOS Genetics: published April 21, 2025 | https://doi.org/10.1371/journal.pgen.1011427