Table Of Contents Page, PNAS Volume 122, Number 48
Special Feature
Genetics of Canine Domestication, Migration, and Behavior
Many contemporary breed dogs display reduced genomic health compared to mixed-breed
dogs, including reduced heterozygosity and increased genetic load, likely due to strong
directed breeding. Lack of historical genomes, however, has made it difficult to ...
The multi-millennia-long history between dogs and humans has placed them at the forefront
of archaeological and genomic research. Despite ongoing efforts including the analysis
of ancient dog and wolf genomes, many questions remain regarding the ...
The European colonial expansion had dramatic consequences on both Indigenous Peoples
and local fauna. In Australia, the degree to which the arrival of Europeans and their
dogs impacted the ecology and ancestry of dingoes is contentious. To test for gene
...
Dogs evolved through interactions between people and gray wolves during the Late Pleistocene
and have been ubiquitous in human societies ever since. Instances of wolf-to-dog introgression
are rare, but adaptive introgression has been shown in association ...
Dogs were domesticated at least once from a yet-unidentified wolf population at least
~15,000 y ago. However, how domestication took place is a topic of ongoing debate,
and the ability of human groups to manage wolves in their communities during early
...
Dogs display temperamental and behavioral variation between individuals, just as psychiatric,
temperamental, and cognitive traits vary in humans. In both species, these traits
are highly heritable, yet causal genes remain incompletely understood. We ...
Genetic tests for behavioral and personality traits in dogs are now being marketed
to pet owners, but their predictive accuracy has not been validated. To evaluate the
reliability of such tests, we analyzed data from Darwin’s Ark, a community science
...
The polygamous mating system of free-ranging domestic dogs (FRDs) contrasts with the
social monogamy typical of gray wolves and all other wild canids. The transition to
polygamy in dogs could have been initiated by a shift from apex predator to human
...
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In nature, plants cope with various pathogens that compete for cellular resources
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Perennial plants, such as trees native to temperate and boreal regions, exhibit meristems
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...
The dynamic organization of chromatin governs gene expression by regulating DNA accessibility.
In plants, light not only initiates photomorphogenesis but also reshapes higher-order
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Population Biology
Following the late 2022 transition from its “dynamic zero-COVID” policy, China experienced
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Inference of Ancestral Recombination Graphs (ARGs) is of central interest in the analysis
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Psychological and Cognitive Sciences
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Systems Biology
Deploying motile nanosized particles, also known as “nanobots,” in the human body
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a swarm of nanobots locating a single cancerous region and treating it by releasing
an ...
Corrections
Retraction
Cover image: Pictured is Tilly, a five-year-old, nonbreed dog, on the banks of the Potomac River. A collection of articles in The Genetics of Canine Domestication, Migration, and Behavior Special Feature explores the evolution of dogs from wolves and how domestication has shaped dogs’ genomes and behavior. Together, the articles provide insight into topics including gene flow between dogs and wolves, the history of inbreeding in dogs, the evolution of dogs’ mating systems, the genetic basis of canine behavior, and links between canine behavior and human psychiatric traits. See the Introduction to the Special Feature, e2528616122. Image credit: Logan Kistler (Smithsonian Institution, Washington, DC).
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