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Brought to you by The Vilcek Foundation VOLUME 384 | ISSUE 6697 | 17 MAY 2024 Editorial Editorial Energy transition needs new materials By Chad A. Mirkin, Edward H. Sargent, et al. Read more News In Brief News at a glance Read more In Depth  |  Public Health Haiti’s health researchers persevere amid chaos By Meredith Wadman “Heroic network” forges ahead as gang violence dominates life and landscape Read more In Depth  |  Psychology Nonsensical results plague online social science tool By Cathleen O’Grady Data quality suffers in some MTurk studies—but participant screening and other safeguards can help Read more In Depth  |  Biomedicine Why are elite athletes prone to heart arrhythmias? By Jennifer Couzin-Frankel Studying cardiac effects of extreme exercise could yield clues to atrial fibrillation Read more In Depth  |  Cosmology NSF halts South Pole probe of cosmic inflation By Adrian Cho Aging infrastructure there cannot support suite of new telescopes, agency says Read more In Depth  |  Materials Science AI-driven robots discover record-setting laser compound By Robert F. Service Automated labs spread across the globe create, test, and assemble materials—no humans required Read more In Depth  |  U.S. Research Policy Plan to alter access to health data draws ire By Meredith Wadman Universities could no longer store Medicare and Medicaid data, and costs would rise Read more Feature The inflamed brain By Richard Stone Autoimmune conditions underlie some cases of psychosis. Scientists are expanding their search for patients, who often benefit from treatment Read more Insights Perspective  |  Medicine Progress on priming HIV-1 immunity By Rogier W. Sanders, John P. Moore Four new studies inform on the multistep path to generate broadly active HIV-1 antibodies Read more Perspective  |  Ecology Tool use promotes dental health By Barbara C. Klump Using tools increases foraging success in sea otters and protects their teeth from damage Read more Perspective  |  Physics Engineering colloidal crystals molecule by molecule By Zhe Li, Chengde Mao DNA particles are programmed to assemble with precision into complex lattices Read more Perspective  |  Medicine The complexity of physician power By Laura Nimmon Inequitable variation in physician effort and resource use is revealed Read more Perspective  |  Retrospective Lubert Stryer (1938—2024) By Jeremy Berg Trailblazing biochemist and author Read more Policy Forum  |  Ocean Taking climate-smart governance to the high seas By Catarina Frazão Santos, Tundi Agardy, et al. Comprehensive spatial planning in international waters is key to achieving ocean sustainability Read more Books et al.  |  Plant Science Plants in the human gaze By Elizabeth Haswell Must other species be like us to earn our respect? Read more Books et al.  |  Experimental Ethics The whistleblowers By C. Fred Alford A bioethicist probes the costs of exposing wrongdoing in medical research Read more Letter Building on NIH’s data sharing policy By Nicole Contaxis, Kelsey Badger, et al. Read more Letter Undergraduate research data crucial to equity By Dustin B. Thoman, Jessi L. Smith, et al. Read more Letter Self-advocacy for young African scientists By Isildo de N. Nganhane, Harith Farooq Read more Research Research Highlights In Science Journals By Sacha Vignieri, Jake S. Yeston, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Ankit Walia, Melissa McCartney, et al. Editors’ selections from the current scientific literature Read more Research Article  |  HIV VACCINES Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates By Jon M. Steichen, Ivy Phung, et al. Read more Research Article  |  HIV VACCINES mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies By Zhenfei Xie, Ying-Cing Lin, et al. Read more Research Article  |  ORGANIC CHEMISTRY Delocalized, asynchronous, closed-loop discovery of organic laser emitters By Felix Strieth-Kalthoff, Han Hao, et al. Read more Research Article  |  CELL BIOLOGY Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms By Yueyue Li, Yanjie Hou, et al. Read more Research Article  |  THERMOELECTRICS Global band convergence design for high-performance thermoelectric power generation in Zintls By Xin Shi, Shaowei Song, et al. Read more Research Article  |  REPRODUCTIVE COST Metabolic loads and the costs of metazoan reproduction By Samuel C. Ginther, Hayley Cameron, et al. Read more Research Article  |  SOLAR CELLS Bandgap-universal passivation enables stable perovskite solar cells with low photovoltage loss By Yen-Hung Lin, Vikram, et al. Read more Research Article  |  PHOTONIC BANDGAPS Inverse design of a pyrochlore lattice of DNA origami through model-driven experiments By Hao Liu, Michael Matthies, et al. Read more Research Article  |  PHOTONIC BANDGAPS Diamond-lattice photonic crystals assembled from DNA origami By Gregor Posnjak, Xin Yin, et al. Read more Research Article  |  CANCER DNA damage induces p53-independent apoptosis through ribosome stalling By Nicolaas J. Boon, Rafaela A. Oliveira, et al. Read more Research Article  |  ORGANIC CHEMISTRY Enantioselective remote methylene C−H (hetero)arylation of cycloalkane carboxylic acids By Tao Zhang, Zi-Yu Zhang, et al. Read more Research Article  |  ADAPTIVE TOOL USE Tool use increases mechanical foraging success and tooth health in southern sea otters (Enhydra lutris nereis) By Chris J. Law, M. Tim Tinker, et al. Read more Research Article  |  HEALTH ECONOMICS How power shapes behavior: Evidence from physicians By Stephen D. Schwab, Manasvini Singh Read more Research Article  |  CRISPR Repair of CRISPR-guided RNA breaks enables site-specific RNA excision in human cells By Anna Nemudraia, Artem Nemudryi, et al. Read more Research Article  |  ORGANIC CHEMISTRY Remote proton elimination: C–H activation enabled by distal acidification By Phillip S. Grant, Miloš Vavrík, et al. Read more Careers Working Life Starting over By Ashley Ruba Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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