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Brought to you by Science Webinars VOLUME 384 | ISSUE 6698 | 24 MAY 2024 Special Issue Introduction to Special Issue Decoding the Brain By Yevgeniya Nusinovich A cell-by-cell look at neuropsychiatric diseases Read more Perspective  |  Decoding The Brain Mapping the brain’s gene-regulatory maze By Gaia Novarino, Christoph Bock DNA sequences are connected to genes and functions in the developing and adult brain Read more Research Article  |  PSYCHENCODE2 Single-cell multi-cohort dissection of the schizophrenia transcriptome By W. Brad Ruzicka, Shahin Mohammadi, et al. Read more Research Article  |  PSYCHENCODE2 Massively parallel characterization of regulatory elements in the developing human cortex By Chengyu Deng, Sean Whalen, et al. Read more Research Article  |  PSYCHENCODE2 Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain By Cindy Wen, Michael Margolis, et al. Read more Research Article  |  PSYCHENCODE2 A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex By Louise A. Huuki-Myers, Abby Spangler, et al. Read more Research Article  |  PSYCHENCODE2 Molecular cascades and cell typespecific signatures in ASD revealed by single-cell genomics By Brie Wamsley, Lucy Bicks, et al. Read more Research Article  |  PSYCHENCODE2 Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood By Nikolaos P. Daskalakis, Artemis Iatrou, et al. Read more Research Article  |  PSYCHENCODE2 Genetic regulation of cell type–specific chromatin accessibility shapes brain disease etiology By Biao Zeng, Jaroslav Bendl, et al. Read more Research Article  |  PSYCHENCODE2 Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms By Ashok Patowary, Pan Zhang, et al. Read more Research Article  |  PSYCHENCODE2 Single-cell genomics and regulatory networks for 388 human brains By Prashant S. Emani, Jason J. Liu, et al. Read more Editorial Editorial Pursuing a smoke-free generation By Lawrence O. Gostin Read more News In Brief News at a glance Read more In Depth  |  Academic Integrity Archaeologists accused of theft, bullying, abuse of power By Martin Enserink Couple at Leiden University broke norms for 3 decades, investigators say Read more In Depth  |  COVID-19 U.S. blocks funding for pandemic research group By Jocelyn Kaiser EcoHealth Alliance mishandled grant that helped fund virus studies in China, officials say Read more In Depth  |  Marine Science Alvin, the iconic submersible, plunges deeper than ever By Warren Cornwall After $50 million upgrade, U.S. research sub can reach 99% of the ocean floor Read more In Depth  |  Astronomy Astronomers find long-missing dwarf galaxies—too many of them By Jonathan O’Callaghan Apparent overabundance means theories of how galaxies took shape in the early universe may need adjusting Read more In Depth  |  Infectious Diseases A bird flu vaccine for cows? It’s complicated By Jon Cohen Market uncertainties, safety rules, and export worries stand in way of H5N1 shots for cattle Read more In Depth  |  Invasive Species How the German cockroach conquered the world By Darren Incorvaia DNA study implicates medieval warfare and colonial trade Read more Feature Communication breakdown By Mitch Leslie Faulty messaging between organs could make us old Read more Insights Expert Voices Medical forecasting By Eric J. Topol Read more Perspective  |  Perovskites Unlocking interfaces in photovoltaics By Yun Xiao, Xiaoyu Yang, et al. Eliminating defects at interfaces enables perovskites to approach efficiency limits Read more Perspective  |  Development Multistage maturation optimizes vision By Pascal Mamassian Late development of color vision improves object recognition Read more Perspective  |  Medicine An emerging target for male contraception By Jerrett Holdaway, Gunda I. Georg An inhibitor of a nonhormonal target is identified using a DNA-encoded chemical library Read more Perspective  |  Astronomy A struggle to reionize the Universe? By Claudia Scarlata Reservoirs of neutral hydrogen may block ionizing radiation from escaping distant galaxies Read more Perspective  |  Retrospective Diana H. Wall (1943–2024) By Jane Lubchenco, Kathleen A. Galvin Pioneering Antarctic ecologist and ambassador for soil health Read more Policy Forum  |  Artificial Intelligence Managing extreme AI risks amid rapid progress By Yoshua Bengio, Geoffrey Hinton, et al. Preparation requires technical research and development, as well as adaptive, proactive governance Read more Books et al.  |  Anthropology Fathers and their children By Robert A. Nye An anthropologist uncovers the rich history of paternal care Read more Books et al.  |  Medicine The cesarean section, in context By Tara Mulder A journalist confronts the often unseen elements that influence birthing practices Read more Letter Hope for limestone langurs’ conservation By Penglai Fan, Michael J. Lawes, et al. Read more Letter The value of field research in academia By Kasim Rafiq, Neil R. Jordan, et al. Read more Letter  |  Life in Science Women’s safety in Brazil’s forests By Marina T. Zaluar, Mariana M. Vale, et al. Read more Research Research Highlights In Science Journals By Sacha Vignieri, Marc S. Lavine, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Brad Wible, Yevgeniya Nusinovich, et al. Editors’ selections from the current scientific literature Read more Research Article  |  COMPARATIVE BEHAVIOR Crows “count” the number of self-generated vocalizations By Diana A. Liao, Katharina F. Brecht, et al. Read more Research Article  |  SOLAR CELLS Chiral-structured heterointerfaces enable durable perovskite solar cells By Tianwei Duan, Shuai You, et al. Read more Research Article  |  REPRODUCTION Reversible male contraception by targeted inhibition of serine/threonine kinase 33 By Angela F. Ku, Kiran L. Sharma, et al. Read more Research Article  |  GALAXIES Strong damped Lyman-α absorption in young star-forming galaxies at redshifts 9 to 11 By Kasper E. Heintz, Darach Watson, et al. Read more Research Article  |  SURFACE SCIENCE Synthesis and characterization of low-dimensional N-heterocyclic carbene lattices By Boyu Qie, Ziyi Wang, et al. Read more Research Article  |  ARCHAEOBOTANY Rice’s trajectory from wild to domesticated in East Asia By Jianping Zhang, Leping Jiang, et al. Read more Research Article  |  VISION Impact of early visual experience on later usage of color cues By Marin Vogelsang, Lukas Vogelsang, et al. Read more Research Article  |  BATTERIES Unrecoverable lattice rotation governs structural degradation of single-crystalline cathodes By Weiyuan Huang, Tongchao Liu, et al. Read more Research Article  |  CELL BIOLOGY Demixing is a default process for biological condensates formed via phase separation By Shihan Zhu, Zeyu Shen, et al. Read more Errata Erratum for the Research Article “Size, distribution, and vulnerability of the global soil inorganic carbon” by Y. Huang et al. Read more Errata Erratum for the Report “SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins” by L. Busino et al. Read more Careers Working Life Multiple lenses By Rachel E. Baker Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. 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