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Brought to you by New England Biolabs VOLUME 384 | ISSUE 6701 | 14 JUN 2024 Editorial Editorial Scientists in exile By Gary E. Machlis, Franklin A. Carrero-Martinez Read more News In Brief News at a glance Read more In Depth  |  Mental Health Psychedelics field looks ahead after FDA advisers’ rejection By Kai Kupferschmidt Reeling from negative vote on MDMA-assisted PTSD therapy, researchers seek lessons for future studies Read more In Depth  |  Space Medicine Astronauts face health risks—even on short trips in space By Ramin Skibba New studies include health data collected from space tourists on first privately funded orbital mission Read more In Depth  |  Archaeology Sacrificed Maya boys tied to myth of ‘Hero Twins’ By Andrew Curry Ancient DNA shows continuity between living and ancient Maya communities Read more In Depth  |  Astronomy Hubble telescope down to last gyroscopes, limiting science By Michael Greshko Despite failing hardware, NASA has no plans to pursue a servicing mission to the aging, iconic instrument Read more In Depth  |  Scientific Integrity New probe finds misconduct by star botanist By Charles Piller Steven Newmaster had been cleared, but fresh inquiry concludes he likely made up data Read more In Depth  |  Biomedicine New Alzheimer’s drug clears FDA advisory vote despite unknowns By Jennifer Couzin-Frankel Pivotal trial of Eli Lilly’s donanemab leaves questions about how to prescribe it and minimize risks Read more In Depth  |  Philanthropy Winners of prestigious Sackler prize call for name change By Jop de Vrieze Biophysics prize from Tel Aviv University bears the family’s name despite its role in opioid epidemic Read more Feature Signs of science By Dimitri Selibas CyberTracker, software developed in collaboration with Indigenous trackers, is enabling almost anyone to collect complex biodiversity data Read more Insights Expert Voices Digitalization paving the ways for sustainable chemistry: switching on more green lights By Vânia Zuin Zeidler Read more Perspective  |  Toxicology Canine sentinels and our shared exposome By Courtney Sexton, Audrey Ruple Dogs are distinctly positioned to be indicators of human health and well-being Read more Perspective  |  Biogeochemistry Speciation patterns of zinc in ocean particles By Gregory Cutter Different particulate zinc forms ultimately affect marine biological productivity Read more Perspective  |  Medicine Remedy hope for polycystic ovary syndrome By Elisabet Stener-Victorin Antimalarial suppresses ovarian androgen synthesis to relieve polycystic ovary syndrome Read more Perspective  |  Medicine Gene editing flows to the lungs By Mattijs Bulcaen, Marianne S. Carlon Intravenous targeting of airway basal cells for cystic fibrosis gene therapy overcomes lung barriers Read more Policy Forum  |  Environmental Economics A market for 30x30 in the ocean By Juan Carlos Villasenor-Derbez, Christopher Costello, et al. Marine protections could benefit from trade in obligations Read more Books et al.  |  Neuroscience Face value By Christopher Kemp With candor and humor, a journalist offers an intimate portrait of faceblindness Read more Books et al.  |  Physics Rethinking quantum orthodoxy By Paul Halpern A physicist makes the case for a deterministic alternative to quantum mechanics Read more Letter Threats posed by water transfer in Iran By Alireza Mohammadi, Ali Azareh, et al. Read more Letter Rare earth element mining threatens Malaysia’s biodiversity By Xiangbo Yin, Lee Ping Ang, et al. Read more Letter  |  Past as Prologue A neuroscientist’s duty to Black ancestors By Chandler Wright Read more Research Research Highlights In Science Journals By Bianca Lopez, Phil Szuromi, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Corinne N. Simonti, Caroline Ash, et al. Editors’ selections from the current scientific literature Read more Research Article  |  BICCN Integrated platform for multiscale molecular imaging and phenotyping of the human brain By Juhyuk Park, Ji Wang, et al. Read more Research Article  |  LIVER REGENERATION Metabolic inflexibility promotes mitochondrial health during liver regeneration By Xun Wang, Cameron J. Menezes, et al. Read more Research Article  |  ENDOCRINOLOGY Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction By Yang Liu, Jing-jing Jiang, et al. Read more Research Article  |  MICROBIAL ECOLOGY A phage tail–like bacteriocin suppresses competitors in metapopulations of pathogenic bacteria By Talia Backman, Sergio M. Latorre, et al. Read more Research Article  |  STREAM ECOLOGY Human activities shape global patterns of decomposition rates in rivers By S. D. Tiegs, K. A. Capps, et al. Read more Research Article  |  GENE EDITING In vivo editing of lung stem cells for durable gene correction in mice By Yehui Sun, Sumanta Chatterjee, et al. Read more Research Article  |  TEXTILES Spectrally engineered textile for radiative cooling against urban heat islands By Ronghui Wu, Chenxi Sui, et al. Read more Research Article  |  THERMODYNAMICS Melting entropy of crystals determined by electron-beam–induced configurational disordering By Dongxin Liu, Jiarui Fu, et al. Read more Research Article  |  GENE THERAPY An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery By Qin Huang, Ken Y. Chan, et al. Read more Research Article  |  SOLAR CELLS Two-dimensional perovskite templates for durable, efficient formamidinium perovskite solar cells By Siraj Sidhik, Isaac Metcalf, et al. Read more Research Article  |  OCEAN CHEMISTRY Biogenic-to-lithogenic handoff of particulate Zn affects the Zn cycle in the Southern Ocean By J. Duan, R. Cloete, et al. Read more Research Article  |  PLANT SCIENCE YABBY and diverged KNOX1 genes shape nodes and internodes in the stem By Katsutoshi Tsuda, Akiteru Maeno, et al. Read more Research Article  |  STRUCTURAL BIOLOGY Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I By Daniel N. Grba, John J. Wright, et al. Read more Research Article  |  WATER Probing structural superlubricity of two-dimensional water transport with atomic resolution By Da Wu, Zhengpu Zhao, et al. Read more Research Article  |  MEDICINAL CHEMISTRY Highly pure DNA-encoded chemical libraries by dual-linker solid-phase synthesis By Michelle Keller, Dimitar Petrov, et al. Read more Careers Working Life A family’s sacrifice By Abdullah M. Abudayyeh Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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