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Brought to you by Science Webinars VOLUME 384 | ISSUE 6702 | 21 JUN 2024 Editorial Editorial Reducing nuclear dangers By Matthew Bunn Read more News In Brief News at a glance Read more In Depth  |  Agricultural Science Wheat scientists unveil historic ‘gold mine’ By Erik Stokstad Genome sequencing of century-old collection could help breeders restore long-lost traits Read more In Depth  |  United Kingdom As U.K. election nears, major parties reveal their science plans By Holly Else All pledge support for research but would restrict immigration, dismaying researchers Read more In Depth  |  Scientific Integrity Settlement over China funding puts institutions on notice By Jeffrey Mervis Cleveland Clinic fined $7.6 million for alleged mismanagement of NIH grants Read more In Depth  |  Science Policy Republicans float plan to overhaul NIH By Jocelyn Kaiser Lawmakers propose reducing 27 institutes to 15 Read more In Depth  |  Infectious Diseases Wild poliovirus makes comeback in Afghanistan and Pakistan By Leslie Roberts 2024 target of ending all transmission will likely be missed Read more In Depth  |  Earth Sciences Ancient earthquake likely rerouted the Ganges By Eli Kintisch Discovery of new seismic concern stokes flooding fear for densely populated delta region Read more Feature No place like home By Daniel Clery The hunt for Earth-like planets has run into headwinds. Some astronomers are looking for signs of habitability on bigger worlds Read more Insights Expert Voices Approaching the quantum limit of contact resistance in van der Waals layered semiconductors By Young Hee Lee Read more Perspective  |  Atmospheric Chemistry Mapping urban haze By Thomas Karl Direct airborne measurements of emission fluxes reveal major sources over California Read more Perspective  |  Cell Biology Cellular senescence in normal physiology By João Pedro de Magalhães Long associated with aging, senescent cells can promote health and have physiological roles Read more Perspective  |  Cancer An unexpected corridor to brain metastasis By Lea Monteran, Neta Erez Breast cancer cells migrate from the bone marrow to the leptomeninges Read more Perspective  |  Cancer JAKing up immunity By Massimo Gadina, John J. O’Shea Janus kinase (JAK) inhibitors improve antitumor responses Read more Perspective  |  Retrospective Daniel C. Dennett (1942—2024) By Rafael Yuste, Michael Levin Philosopher and science advocate Read more Policy Forum  |  Artificial Intelligence GPTs are GPTs: Labor market impact potential of LLMs By Tyna Eloundou, Sam Manning, et al. Research is needed to estimate how jobs may be affected Read more Books et al.  |  Review Roundup Ten must-read science histories By Tiago Saraiva, Emily Pawley, et al. Read more Letter Sustainable development in global border regions By Yi Cheng, Zhenci Xu, et al. Read more Letter Sex-based differences affect conservation By Elena Gissi, R. Terry Bowyer, et al. Read more Letter Plastic foam pollution from Chinese fisheries By Hui Wang, Peng Liu, et al. Read more Research Research Highlights In Science Journals By Marc S. Lavine, Sacha Vignieri, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Ekeoma E. Uzogawa, L. Bryan Ray, et al. Editors’ selections from the current scientific literature Read more Research Article  |  CLINICAL TRIALS JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma By Jaroslav Zak, Isaraphorn Pratumchai, et al. Read more Research Article  |  CLINICAL TRIALS Combined JAK inhibition and PD-1 immunotherapy for non–small cell lung cancer patients By Divij Mathew, Melina E. Marmarelis, et al. Read more Research Article  |  CANCER Breast cancer exploits neural signaling pathways for bone-to-meninges metastasis By Andrew E. Whiteley, Danhui Ma, et al. Read more Research Article  |  DRUG DISCOVERY AlphaFold2 structures guide prospective ligand discovery By Jiankun Lyu, Nicholas Kapolka, et al. Read more Research Article  |  NANOMATERIALS Carbon nanotube fibers with dynamic strength up to 14 GPa By Xinshi Zhang, Xudong Lei, et al. Read more Research Article  |  AIR POLLUTION Temperature-dependent emissions dominate aerosol and ozone formation in Los Angeles By Eva Y. Pfannerstill, Caleb Arata, et al. Read more Research Article  |  ADAPTIVE SOCIALITY Ecological disturbance alters the adaptive benefits of social ties By C. Testard, C. Shergold, et al. Read more Research Article  |  CARBON CYCLING Bomb radiocarbon evidence for strong global carbon uptake and turnover in terrestrial vegetation By Heather D. Graven, Hamish Warren, et al. Read more Research Article  |  QUANTUM OPTICS Topological Hong-Ou-Mandel interference By Max Ehrhardt, Christoph Dittel, et al. Read more Research Article  |  FLUID DYNAMICS Selective directional liquid transport on shoot surfaces of Crassula muscosa By Ling Yang, Wei Li, et al. Read more Research Article  |  PHOTOSYNTHESIS Cryo–electron microscopy reveals hydrogen positions and water networks in photosystem II By Rana Hussein, André Graça, et al. Read more Research Article  |  FREQUENCY COMBS Observation of topological frequency combs By Christopher J. Flower, Mahmoud Jalali Mehrabad, et al. Read more Research Article  |  NEUROSCIENCE Top-down brain circuits for operant bradycardia By Airi Yoshimoto, Shota Morikawa, et al. Read more Research Article  |  SPINTRONICS Spin torque–driven electron paramagnetic resonance of a single spin in a pentacene molecule By Stepan Kovarik, Richard Schlitz, et al. Read more Research Article  |  ELECTROCHEMISTRY Water-hydroxide trapping in cobalt tungstate for proton exchange membrane water electrolysis By Ranit Ram, Lu Xia, et al. Read more Errata Erratum for the Perspective “Phylogeny of Methylomes” by A. Jeltsch Read more Careers Working Life Science and fiction By Carlo G. Quintanilla Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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