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VOLUME 385 | ISSUE 6706 | 19 JUL 2024 Editorial Editorial Go/no-go for a Mars samples return By David Southwood Read more News In Brief News at a glance Read more In Depth  |  Human Evolution Oldest human genome comes from a Denisovan By Ann Gibbons 200,000-year-old DNA shows our now-extinct cousins mated with Neanderthals Read more In Depth  |  Planetary Science Vulnerable transistors threaten $5 billion Europa Clipper probe By Paul Voosen NASA investigates flaws in radiation-hardened electronics Read more In Depth  |  Science Museums California Academy of Sciences reeling from new budget cuts By Erik Stokstad Science division gets hit hard to close major funding gap Read more In Depth  |  Oceanography Cruise set to restore critical Indian Ocean mooring array By Vaishnavi Chandrashekar Mostly inoperable since 2020, sensors are key to monsoon forecasts and understanding global climate patterns Read more In Depth  |  Glaciology Scientists at odds over wild plans to slow melting glaciers By Hannah Richter Call to study glacial geoengineering stirs up “civil war” among polar scientists Read more In Depth  |  Global Health High bar for famine declaration delays food aid By Leslie Roberts Lack of humanitarian action during early stages of acute food insecurity takes a heavy toll Read more In Depth  |  Paleoclimate Medieval wine tasting records fill in gaps about Europe’s climate By Paul Voosen Sweetness data help chart temperatures back to the 1400s Read more In Depth  |  Marine Science Bering Strait hit by unprecedented algal bloom By Megan Gannon The toxic organisms, which cause paralytic shellfish poisoning, are moving northward with climate change Read more Feature Making fusion pay By Adrian Cho To fund its vision of generating power from fusion, SHINE Technologies aims first to revolutionize medical isotope production Read more Insights Expert Voices We need better and more PopSci by scientists By Agustín Fuentes Read more Perspective  |  Human Genetics Genomic diversity improves disease discovery for all By Alice Williamson, Segun Fatumo Genomic data from different populations will improve understanding of complex diseases Read more Perspective  |  Chemistry From “forever chemicals” to fluorine-free alternatives By Mohamed Ateia, Martin Scheringer Identifying alternatives to PFAS requires weighing trade-offs and uncertainties Read more Perspective  |  Medicine The benefits of GLP-1 drugs beyond obesity By Daniel J. Drucker Glucagon-like peptide–1–based medicines have weight loss–independent actions Read more Perspective  |  Ecology A hard fruit to swallow By Anna L. Hargreaves, Jake M. Alexander Foraging niches become more specialized toward bird range limits Read more Policy Forum  |  Global Health Artemisinin-resistant malaria in Africa demands urgent action By Mehul Dhorda, Akira Kaneko, et al. Investment in community health workers is essential Read more Books et al.  |  Science Lives Element of surprise By H. Holden Thorp A lively musical shines a stylized spotlight on Marie Curie’s extraordinary life Read more Books et al.  |  Archaeology When civilizations collapse By Thomas E. Levy An archaeologist probes ancient insights on how to cope when things fall apart Read more Letter Stop elephant hunting in Tanzania borderlands By Joyce Poole, Andrew Dobson, et al. Read more Letter Dengue’s economic impact in Brazil By Rodrigo L. Vancini, Marilia S. Andrade, et al. Read more Letter Obesity in Bangladesh: Study food near schools By Md Karimuzzaman Read more Research Research Highlights In Science Journals By Brent Grocholski, Phil Szuromi, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Brad Wible, Sacha Vignieri, et al. Editors’ selections from the current scientific literature Read more Review  |  MICROBIOTA Host control of the microbiome: Mechanisms, evolution, and disease By Jacob Wilde, Emma Slack, et al. Read more Research Article  |  HUMAN GENOMICS Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program By Anurag Verma, Jennifer E. Huffman, et al. Read more Research Article  |  CHEMICAL BIOLOGY Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells By Zhi Lin, Kaitlin Schaefer, et al. Read more Research Article  |  MOLECULAR BIOLOGY The human mitochondrial mRNA structurome reveals mechanisms of gene expression By J. Conor Moran, Amir Brivanlou, et al. Read more Research Article  |  CELL BIOLOGY Live chromosome identifying and tracking reveals size-based spatial pathway of meiotic errors in oocytes By Osamu Takenouchi, Yogo Sakakibara, et al. Read more Research Article  |  PROTEIN DESIGN Binding and sensing diverse small molecules using shape-complementary pseudocycles By Linna An, Meerit Said, et al. Read more Research Article  |  PROTEIN DESIGN Sculpting conducting nanopore size and shape through de novo protein design By Samuel Berhanu, Sagardip Majumder, et al. Read more Research Article  |  PLANT SCIENCE Periodic cytokinin responses in Lotus japonicus rhizobium infection and nodule development By Takashi Soyano, Akira Akamatsu, et al. Read more Research Article  |  CATALYSIS Defective TiOx overlayers catalyze propane dehydrogenation promoted by base metals By Sai Chen, Yiyi Xu, et al. Read more Research Article  |  DIELECTRICS Dynamics of high-speed electrical tree growth in electron-irradiated polymethyl methacrylate By Kathryn M. Sturge, Noah Hoppis, et al. Read more Research Article  |  ORGANIC CHEMISTRY Ph3PCN2: A stable reagent for carbon-atom transfer By Taichi Koike, Jhen-Kuei Yu, et al. Read more Research Article  |  SPIN GENERATION Two-dimensional chiral perovskites with large spin Hall angle and collinear spin Hall conductivity By Ibrahim Abdelwahab, Dushyant Kumar, et al. Read more Research Article  |  ORGANIC CHEMISTRY Synthesis of a stable crystalline nitrene By Marvin Janssen, Thomas Frederichs, et al. Read more Research Article  |  ICE SHEETS Ice sheet–free West Antarctica during peak early Oligocene glaciation By J. P. Klages, C.-D. Hillenbrand, et al. Read more Research Article  |  INORGANIC CHEMISTRY Synthesis and reactivity of an N-heterocyclic carbene–stabilized diazoborane By Chonghe Zhang, Christopher C. Cummins, et al. Read more Research Article  |  BIOGEOGRAPHY Birds optimize fruit size consumed near their geographic range limits By Lucas P. Martins, Daniel B. Stouffer, et al. Read more Errata Erratum for the Research Article “The lysosomal Rag-Ragulator complex licenses RIPK1– and caspase-8–mediated pyroptosis by Yersinia” by Z. Zheng et al. Read more Careers Working Life My weekly reset By Paul Hibbing Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. 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