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Brought to you by Science Webinars VOLUME 386 | ISSUE 6725 | 29 NOV 2024 Editorial Editorial A new vision for American science By Sudip S. Parik, Marcia K. McNutt, et al. Read more News In Brief News at a glance Read more In Depth  |  Scientific Community Researchers and scientific institutions flock to Bluesky By Kai Kupferschmidt After recent changes to Elon Musk’s X, a gradual migration in search of the “old Twitter” turns into a stampede Read more In Depth  |  Biology ‘Dark proteome’ survey reveals thousands of new human genes By Elizabeth Pennisi Database confirms that overlooked segments of the genome code for a multitude of tiny proteins Read more In Depth  |  Chemistry Mining lithium from brines goes electric By Robert F. Service Critical battery metal could be extracted more quickly than in evaporation ponds Read more In Depth  |  Infectious Diseases Children are left behind in Congo’s mpox vaccination drive By Jon Cohen Regulatory and liability issues are delaying immunization of the group most vulnerable to severe disease and death Read more In Depth  |  Research Integrity Fake papers compromise research syntheses By Holly Else “Systematic reviews” that aim to extract broad conclusions from many studies are in peril Read more Feature Eating the Earth By Joel K. Bourne The burgeoning global food trade is a lifeline for billions, but it is fragile and hard on the planet Read more Insights Expert Voices Neither climate laboratory nor knowledge vacuum: What’s at stake for the Global South in the debate around solar geoengineering research By Rose M. Mutiso Read more Perspective  |  Metamaterials Micrometer-sized robotic chameleons By Corentin Coulais, Jorik van de Groep A multifunctional metamaterial can change shape and steer light simultaneously Read more Perspective  |  Evolution Contemporary hominin locomotor diversity By William E. H. Harcourt-Smith Footprints in Kenya show that hominin bipedalism had a complex evolutionary history Read more Perspective  |  Iontronics Droplet-based microprocessors By Jean-Christophe Baret Soft devices made of nanoliter hydrogel beads use ions for computation Read more Perspective  |  Viewpoint: COVID-19 Endothelial inflammation in COVID-19 By Peter Libby Disrupted endothelial function underlies the multiorgan complications of COVID-19 Read more Policy Forum  |  Agriculture Harness agrifood value chains to help farmers be climate smart By Johan Swinnen, Loraine Ronchi, et al. Incentives and structures exist to improve farming practices Read more Books et al.  |  History of Science DNA and deli sandwiches By Luis A. Campos On the anniversary of a pivotal patent, a historian probes biotechnology’s origin story Read more Books et al.  |  Philosophy The philosopher’s intuition By Mary Ellen Hannibal A forgotten scholar sought to reconcile subjective experience with the laws of nature Read more Letter Assessment abuse in African protected areas By Reece Alberts, Francois Retief, et al. Read more Letter Mpox prevention in low-income countries By Xin Yu Yang, Gong Jie Zhang, et al. Read more Research Research Highlights In Science Journals By Yevgeniya Nusinovich, Ekeoma Uzogara, et al. Highlights from the Science family of journals Read more Research Highlights In Science Journals By Yevgeniya Nusinovich, Ekeoma Uzogara, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Bianca Lopez, Sarah H. Ross, et al. Editors’ selections from the current scientific literature Read more Review  |  OPTOELECTRONICS Optoelectronic metadevices By Son Tung Ha, Qitong Li, et al. Read more Research Article  |  DIFFERENTIATION PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance By Meryem B. Baghdadi, Ronja M. Houtekamer, et al. Read more Research Article  |  NEUROSCIENCE Tlr7 drives sex differences in age- and Alzheimer’s disease–related demyelination By Chloe Lopez-Lee, Lay Kodama, et al. Read more Research Article  |  MALARIA Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance By Madeline R. Luth, Karla P. Godinez-Macias, et al. Read more Research Article  |  MOLECULAR BIOLOGY Molecular basis of mRNA delivery to the bacterial ribosome By Michael W. Webster, Adrien Chauvier, et al. Read more Research Article  |  MISINFORMATION Misinformation exploits outrage to spread online By Killian L. McLoughlin, William J. Brady, et al. Read more Research Article  |  CELL BIOLOGY Identification of a factor that accelerates substrate release from the signal recognition particle By Huping Wang, Ramanujan S. Hegde Read more Research Article  |  ANTHROPOLOGY Footprint evidence for locomotor diversity and shared habitats among early Pleistocene hominins By Kevin G. Hatala, Neil T. Roach, et al. Read more Research Article  |  HEMOGLOBIN DISORDERS A tetramer of BCL11A is required for stable protein production and fetal hemoglobin silencing By Ge Zheng, Maolu Yin, et al. Read more Research Article  |  OCEANOGRAPHY Decadal oscillations in the ocean’s largest oxygen-deficient zone By N. N. Duprey, A. D. Foreman, et al. Read more Research Article  |  IONTRONICS Microscale droplet assembly enables biocompatible multifunctional modular iontronics By Yujia Zhang, Cheryl M. J. Tan, et al. Read more Research Article  |  MICROROBOTICS Magnetically programmed diffractive robotics By Conrad L. Smart, Tanner G. Pearson, et al. Read more Research Article  |  MEMBRANES Aromatic-aliphatic hydrocarbon separation with oriented monolayer polyhedral membrane By Hao Sun, Naixin Wang, et al. Read more Research Article  |  METABOLISM Exposure to sugar rationing in the first 1000 days of life protected against chronic disease By Tadeja Gracner, Claire Boone, et al. Read more Research Article  |  HIBERNATION Suppression of neurons in circumventricular organs enables months-long survival without water in thirteen-lined ground squirrels By Madeleine S. Junkins, Ni Y. Feng, et al. Read more Research Article  |  QUANTUM SIMULATION Realization of one-dimensional anyons with arbitrary statistical phase By Joyce Kwan, Perrin Segura, et al. Read more Careers Working Life Racing the clock By Cecilia Padilla Iglesias, Erika C. Freeman Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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