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Brought to you by How Robots Will Facilitate Scientific Discovery VOLUME 386 | ISSUE 6728 | 20 DEC 2024 Editorial Editorial Tolerance on trial By H. Holden Thorp Read more News In Brief News at a glance Read more In Depth  |  Science Policy Climate scientists gird for Trump administration By Paul Voosen Trump agents have vowed to squash research and fire adversaries Read more In Depth  |  Research Integrity AI-generated commentaries flood journals, distort metrics By Frederik Joelving Shoddy commentaries are a quick and dirty route to higher impact numbers Read more In Depth  |  Mental Health Can psychedelics improve well-being in autism? By Rachel Nuwer A brace of new studies probes benefits and risks for an understudied group Read more In Depth  |  Science Policy Dismay greets possible ban on Chinese drones By Celina Zhao U.S. scientists studying forests, whales, and more largely rely on devices made in China Read more In Depth  |  Astronomy Mysterious radio pulses traced to dance of stellar dwarfs By Daniel Clery Languorous cosmic beats could be generated by magnetic forces between orbiting stars Read more Feature Congo’s mpox crisis By Jon Cohen For the second time in 2 years, a long-overlooked virus poses a global threat. Can it be contained? Read more Insights Expert Voices The struggles and joys of being an Indigenous researcher in the academy By Tahu Kukutai Read more Expert Voices Experiments outside the lab come with new responsibilities By Jack Stilgoe Read more Perspective  |  Plant Immunity A common immune response node in diverse plants By Jeffery L. Dangl, Jonathan D. G. Jones Small molecules activate a defense mechanism shared by all flowering plants Read more Perspective  |  Immunology Platform influencers—host RNA control of antiviral immunity By Sonja M. Best, Adam Hage Cellular RNAs directly regulate the activity of an antiviral immune signaling complex Read more Perspective  |  Chiral Materials Thermal radiation with a twist By Sathwik Bharadwaj, Zubin Jacob Carbon nanotube filaments with a twisted geometry emit spinning heat waves at high temperatures Read more Perspective  |  Neuroscience Aged neurons don’t register energy need By Deniz Bingul, Scott F. Owen Neuronal activity and mitochondrial gene expression become decoupled in aged mice Read more Policy Forum  |  Biosecurity Confronting risks of mirror life By Katarzyna P. Adamala, Deepa Agashe, et al. Broad discussion is needed to chart a path forward Read more Books et al.  |  Public Health Return of the phage By Tara C. Smith The pros and cons of alternative antimicrobial therapies are worth considering in an age of antibiotic resistance Read more Books et al.  |  Science Lives Becoming Roger Penrose By Graham Farmelo A journalist paints a complex and rewarding portrait of the mathematical physicist Read more Letter FDA should consider drug-therapy regimens By Eero Castrén, Claus Normann Read more Letter Conflict drives mpox epidemic in eastern DRC By Misaki Wayengera Read more Letter Red tape strangles viral surveillance programs By Al Ozonoff, Annie Elong Ngono, et al. Read more Research Research Highlights In Science Journals By Ian S. Osborne, Keith T. Smith, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Sacha Vignieri, Jake S. Yeston, et al. Editors’ selections from the current scientific literature Read more Research Article  |  INNATE IMMUNITY Cellular RNA interacts with MAVS to promote antiviral signaling By Nandan S. Gokhale, Russell K. Sam, et al. Read more Research Article  |  PALEOBIOLOGY Quantifying the global biodiversity of Proterozoic eukaryotes By Qing Tang, Wentao Zheng, et al. Read more Research Article  |  AGING Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice By Wenwen Li, Jiarui Li, et al. Read more Research Article  |  PLANT SCIENCE A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids By Adam Jozwiak, Sayantan Panda, et al. Read more Research Article  |  PLANT SCIENCE A scaffold protein manages the biosynthesis of steroidal defense metabolites in plants By Marianna Boccia, Danny Kessler, et al. Read more Research Article  |  GEOMICROBIOLOGY Hydrogenotrophic methanogens overwrite isotope signals of subsurface methane By Daisuke Mayumi, Hideyuki Tamaki, et al. Read more Research Article  |  MOIRÉ PHYSICS Hydrodynamic moiré superlattice By Guoqiang Xu, Xue Zhou, et al. Read more Research Article  |  OPTOMECHANICS Quantum collective motion of macroscopic mechanical oscillators By Mahdi Chegnizadeh, Marco Scigliuzzo, et al. Read more Research Article  |  IMMUNOLOGY Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses By Vamsee Mallajosyula, Saborni Chakraborty, et al. Read more Research Article  |  LUNAR GEOLOGY A sample of the Moon’s far side retrieved by Chang’e-6 contains 2.83-billion-year-old basalt By Zexian Cui, Qing Yang, et al. Read more Research Article  |  CHIRAL MATERIALS Bright, circularly polarized black-body radiation from twisted nanocarbon filaments By Jun Lu, Hong Ju Jung, et al. Read more Research Article  |  PLANT IMMUNITY A canonical protein complex controls immune homeostasis and multipathogen resistance By Yue Wu, Weiying Xu, et al. Read more Research Article  |  PLANT IMMUNITY Activation of a helper NLR by plant and bacterial TIR immune signaling By Hua Yu, Weiying Xu, et al. Read more Research Article  |  ORGANIC CHEMISTRY Biocatalytic C–H oxidation meets radical cross-coupling: Simplifying complex piperidine synthesis By Jiayan He, Kenta Yokoi, et al. Read more Research Article  |  MOLECULAR BIOLOGY Noncanonical role of ALAS1 as a heme-independent inhibitor of small RNA–mediated silencing By Seungjae Lee, Sangmi Lee, et al. Read more Careers Working Life A step back, not a setback By Monisha Madhumita Read more Association Affairs Association Affairs 2024 AAAS Kavli Science Journalism Award Winners Named By Earl Lane, Emily Hughes Seven awards went to international journalists and two to international/US collborations Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. 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