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Brought to you by The Noster & Science Microbiome Prize VOLUME 387 | ISSUE 6730 | 10 JAN 2025 Editorial Editorial Optimism for a global plastics treaty By Stephen Fletcher, Tegan Evans Read more News In Brief News at a glance Read more In Depth  |  Biomedicine Fish could personalize cancer treatments By Mitch Leslie The first clinical trial of zebrafish embryos acting as cancer “avatars” will start soon Read more In Depth  |  Community ‘Good boring’: How Bluesky is shaping scientists’ discourse By Kai Kupferschmidt The fast-growing platform may be more equitable than X, but gives scientists a smaller stage Read more In Depth  |  Mycology Dogs sniff out truffles—in the name of science By Christie Wilcox Their keen noses are helping researchers uncover the diversity of the Pacific Northwest’s underground fungi Read more In Depth  |  Reproducibility NIH sets out to double check biomedical studies By Jocelyn Kaiser But so far, few investigators seem interested in having their work repeated Read more In Depth  |  Neuroscience How a neurotransmitter drives brainwashing during sleep By Mitch Leslie Pulsating blood vessels push fluid into and out of the brains of slumbering mice Read more Feature Losing ground By Warren Cornwall Starved of sediment and losing protective reeds, the Mississippi River’s sprawling delta could soon vanish Read more Feature A river with a mind of its own By Warren Cornwall Read more Insights Expert Voices Grazing can reduce wildfire risk amid climate change By Valério D. Pillar, Gerhard E. Overbeck Read more Perspective  |  Carbon Capture Built to remove carbon By Christopher Bataille Building materials could facilitate long-term removal of atmospheric carbon dioxide Read more Perspective  |  Biomechanics A long-ignored skeletal tissue filled with oil By Viviana Hermosilla Aguayo, Licia Selleri Lipid-rich cartilage points to nonmetabolic functions of lipid vacuoles in mammals Read more Perspective  |  Cancer Ena-bile-ing liver cancer growth By Wolfram Goessling Bile acids differentially affect immune cell responses to liver cancer Read more Perspective  |  Neurophysiology Stress drives a switch in sex preference By Bitna Joo, Kay M. Tye Distinct brain circuits control sex preferences in mice Read more Policy Forum  |  Energy Policy Impacts of EPA’s finalized power plant greenhouse gas standards By John Bistline, Aaron Bergman, et al. Emissions reductions may be met with relatively small costs Read more Books et al.  |  Science and Society The many misuses of the rape kit By Deborah Blum Haphazardly applied, frequently lost, and often ignored, the vital forensic tool also has a troubling past Read more Books et al.  |  Psychology Failure to replicate By Elizabeth Lunbeck A historian confronts the complicated origins and uncertain future of priming research Read more Letter Green building materials undercut EU plastic goals By Anna Cipriani, Federico Lugli, et al. Read more Letter  |  Outside the Tower Teaming up to save Argentine Chaco forests By Matias Mastrangelo, Micaela Camino Read more Research Research Highlights In Science Journals By Jesse Smith, Marc S. Lavine, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Corinne Simonti, L. Bryan Ray, et al. Editors’ selections from the current scientific literature Read more Research Article  |  EVOLUTION Local genetic adaptation to habitat in wild chimpanzees By Harrison J. Ostridge, Claudia Fontsere, et al. Read more Research Article  |  NANOSCOPIC IMAGING Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy By Arindam Ghosh, Mara Meub, et al. Read more Research Article  |  NEUROSCIENCE Sexually dimorphic dopaminergic circuits determine sex preference By Anqi Wei, Anran Zhao, et al. Read more Research Article  |  CELL BIOLOGY Superstable lipid vacuoles endow cartilage with its shape and biomechanics By Raul Ramos, Kim T. Pham, et al. Read more Research Article  |  EVOLUTIONARY BIOLOGY Parallel gene expansions drive rapid dietary adaptation in herbivorous woodrats By Dylan M. Klure, Robert Greenhalgh, et al. Read more Research Article  |  TOPOLOGICAL PHYSICS Photonic axion insulator By Gui-Geng Liu, Subhaskar Mandal, et al. Read more Research Article  |  EVOLUTION Dietary breadth in kangaroos facilitated resilience to Quaternary climatic variations By Samuel D. Arman, Grant A. Gully, et al. Read more Research Article  |  TROPICAL FORESTS Tropical forest clearance impacts biodiversity and function, whereas logging changes structure By Charles J. Marsh, Edgar C. Turner, et al. Read more Research Article  |  CARBON SEQUESTRATION Building materials could store more than 16 billion tonnes of CO2 annually By Elisabeth Van Roijen, Sabbie A. Miller, et al. Read more Research Article  |  CRYOSPHERE Linear-viscous flow of temperate ice By Collin M. Schohn, Neal R. Iverson, et al. Read more Research Article  |  SOLAR CELLS Wafer-scale monolayer MoS2 film integration for stable, efficient perovskite solar cells By Huachao Zai, Pengfei Yang, et al. Read more Research Article  |  CANCER Bile acid synthesis impedes tumor-specific T cell responses during liver cancer By Siva Karthik Varanasi, Dan Chen, et al. Read more Research Article  |  THERMOELECTRICS Quadruple-band synglisis enables high thermoelectric efficiency in earth-abundant tin sulfide crystals By Shan Liu, Shulin Bai, et al. Read more Research Article  |  MEMBRANES Fluorine-rich poly(arylene amine) membranes for the separation of liquid aliphatic compounds By Yi Ren, Hui Ma, et al. Read more Research Article  |  NEUROSCIENCE Neuroethology of natural actions in freely moving monkeys By Francesca Lanzarini, Monica Maranesi, et al. Read more Retraction Retraction By Alexandre Orthwein, Amélie Fradet-Turcotte, et al. Read more Careers Working Life Finding my true strength By Lan Nguyen Chaplin Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. 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