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Brought to you by The Noster & Science Microbiome Prize VOLUME 387 | ISSUE 6731 | 17 JAN 2025 Editorial Editorial Don’t pretend COVID-19 didn’t happen By Maria D. Van Kerkhove Read more News In Brief News at a glance Read more In Depth  |  Astronomy Energy megaproject threatens giant telescopes By Daniel Clery Glare from proposed green hydrogen plant could degrade views of distant universe Read more In Depth  |  Biomedicine ‘Safe harbor’ gene therapy approach may have first success By Jocelyn Kaiser An obscure gene editor was used to restore a missing liver enzyme in an infant with a devastating metabolic condition Read more In Depth  |  Infectious Diseases Why the ‘Ferrari of viruses’ is surging By Jon Cohen Antibody-dodging norovirus variant may be helping drive a rise in outbreaks Read more In Depth  |  Drug Development AI-designed miniproteins neutralize snake toxins By Christie Wilcox Scientists are turning to AI to make antivenoms cheaper, faster, and more effective Read more In Depth  |  Artificial Intelligence Chinese firm’s large language model makes a splash By Dennis Normile DeepSeek’s open-source model appears to be cheaper and faster to train and run than many others Read more In Depth  |  U.S.-China Relations University of Michigan ends joint effort in China By Richard Stone Republican lawmakers had criticized decades-old ties with Shanghai Jiao Tong University Read more Feature Dust devil By Meredith Wadman Climate change may be driving an expansion of Valley fever, a deadly fungal infection spread by airborne spores Read more Insights Expert Voices “Identity politics” is economic policy By Rohini Pande Read more Perspective  |  Ecology The growing threat of multiyear droughts By David L. Hoover, William K. Smith Understanding and monitoring ecological responses is important as droughts last longer Read more Perspective  |  Neurophysiology Navigating the complexity of touch By Paul D. Marasco Precise cortical microstimulation improves tactile experience in brain–machine interfaces Read more Perspective  |  Physiology Myostatin’s flex on the reproductive hormone axis By Tessa E. Steenwinkel, Stephanie A. Pangas A muscle hormone controls the mammalian reproductive system Read more Perspective  |  Materials Science Not-so-fragile matter By Sameh Tawfick, Ignacio Arretche A three-dimensional chain has strain-dependent solid-like and liquid-like behaviors Read more Books et al.  |  Genetics The ancestral genome’s tale By Kathrin Nägele Narratives that invoke ancient DNA must be crafted with care, argues an archaeologist Read more Books et al.  |  Science and Society Rooting out racial prejudices By Alan Goodman A data-driven portrait of racism exposes the persistent reality of racial biases Read more Letter Enact reforms to protect Bolivia’s forests from fire By Yifan He, Stasiek Czaplicki Cabezas, et al. Read more Letter Bolivian forests hold carbon storage potential By Oswaldo Maillard, Roberto Vides-Almonacid Read more Letter Forestry bill threatens the Amazon’s water cycle By Lucas Ferrante Read more Research Research Highlights In Science Journals By Sacha Vignieri, Marc S. Lavine, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Keith T. Smith, Ekeoma Uzogara, et al. Editors’ selections from the current scientific literature Read more Research Article  |  CANCER Distinct myeloid-derived suppressor cell populations in human glioblastoma By Christina Jackson, Christopher Cherry, et al. Read more Research Article  |  TISSUE IMMUNOLOGY Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis By Marko Šestan, Bruno Raposo, et al. Read more Research Article  |  AGING A panoramic view of cell population dynamics in mammalian aging By Zehao Zhang, Chloe Schaefer, et al. Read more Research Article  |  PLANT SCIENCE Evolution of interorganismal strigolactone biosynthesis in seed plants By Anqi Zhou, Annalise Kane, et al. Read more Research Article  |  POLYMERS Mechanically interlocked two-dimensional polymers By Madison I. Bardot, Cody W. Weyhrich, et al. Read more Research Article  |  ARCHITECTED MATERIALS 3D polycatenated architected materials By Wenjie Zhou, Sujeeka Nadarajah, et al. Read more Research Article  |  MEGADROUGHTS Global increase in the occurrence and impact of multiyear droughts By Liangzhi Chen, Philipp Brun, et al. Read more Research Article  |  SOLAR CELLS Nonalloyed α-phase formamidinium lead triiodide solar cells through iodine intercalation By Yu Zhang, Yanrun Chen, et al. Read more Research Article  |  FUTURE DROUGHT Drought in a warmer, CO2-rich climate restricts grassland water use and soil water mixing By Jesse Radolinski, Matevz Vremec, et al. Read more Research Article  |  ADHESIVES Stereomicrostructure-regulated biodegradable adhesives By Zhen Zhang, Ethan C. Quinn, et al. Read more Research Article  |  CLIMATE CHANGE Climate change and the cost-of-living squeeze in desert lizards By Kristoffer H. Wild, Raymond B. Huey, et al. Read more Research Article  |  ANTHROPOLOGY Australopithecus at Sterkfontein did not consume substantial mammalian meat By Tina Lüdecke, Jennifer N. Leichliter, et al. Read more Research Article  |  NEUROSTIMULATION Tactile edges and motion via patterned microstimulation of the human somatosensory cortex By Giacomo Valle, Ali H. Alamri, et al. Read more Research Article  |  NEUROSCIENCE Reconstitution of synaptic junctions orchestrated by teneurin-latrophilin complexes By Xuchen Zhang, Xudong Chen, et al. Read more Research Article  |  REPRODUCTION Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis By Luisina Ongaro, Xiang Zhou, et al. Read more Careers Working Life Lessons from Lebanon By Peter Kfoury Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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