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Brought to you by Science & PINS Prize for Neuromodulation VOLUME 387 | ISSUE 6732 | 24 JAN 2025 Editorial Editorial Citizen of science By Alan I. Leshner, H. Holden Thorp Read more News In Brief News at a glance Read more In Depth  |  Energy Private fusion firms put bold claims to the test By Daniel Clery Amid skepticism, companies bet that speed and innovation can realize fusion’s promise Read more In Depth  |  Infectious Diseases Mpox drug wins approval in Japan—but it doesn’t work By Jon Cohen Europe previously approved tecovirimat for mpox, based on animal data; the U.S. has stockpiled it for smallpox Read more In Depth  |  Global Health ‘Cataclysmic:’ Experts decry U.S. departure from WHO By Gretchen Vogel Trump’s decision to leave would be a financial blow to the agency and “isolate” the U.S. from health intelligence Read more In Depth  |  Biomedicine Misreported meals skew nutrition research data By Catherine Offord Survey-based studies linking diet patterns to health may be fatally flawed, paper suggests Read more In Depth  |  Science Policy Canadian science girds for shift By Brian Owens Conservative Party expected to win elections later this year Read more Feature The parting of water By Robert F. Service Green hydrogen is key to decarbonizing the world. But the costly, finicky devices that make it need dramatic improvement Read more Insights Perspective  |  Evolution Adaptations in surprising places By Kimberly A. Rosvall Testosterone is controlled while it circulates in the bloodstream Read more Perspective  |  Cell Biology Decoding lysosome communication By Soni Savai Pullamsetti, Rajkumar Savai Lysosome interaction with other organelles may be linked to pulmonary hypertension Read more Perspective  |  Optics Chirality à la carte By Carl P. Romao, Dominik M. Juraschek Light drives a fast switching between achiral and chiral states in a crystal Read more Perspective  |  Neuroscience Expanding the brain’s terrain for reward By Sten Grillner A previously unknown region in the brainstem controls dopamine activity Read more Policy Forum  |  Diversity Behaviorally designed training leads to more diverse hiring By Cansın Arslan, Edward H. Chang, et al. A field experiment provides a promising proof of concept Read more Books et al.  |  Human Anatomy In search of the female form By Tara Mulder Bodies have long resisted easy categorization Read more Books et al.  |  Science and Society Scientists as advocates By Jonathan Wai A sociologist rejects the notion that science is inherently apolitical, urging scholars to join the public square Read more Letter Spatial resolution for forest carbon maps By Laura Duncanson, Neha Hunka, et al. Read more Letter Tanzania’s effective trophy hunting laws By Julius Keyyu, Robert Fyumagwa, et al. Read more Letter A path to US Tribal energy sovereignty By Shane Seibel, Richard Luarkie, et al. Read more Research Research Highlights In Science Journals By Ian S. Osborne, Bianca Lopez, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Sacha Vignieri, Sarah H. Ross, et al. Editors’ selections from the current scientific literature Read more Research Article  |  VASCULAR BIOLOGY Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension By Lloyd D. Harvey, Mona Alotaibi, et al. Read more Research Article  |  OCEAN CARBON Antarctic krill vertical migrations modulate seasonal carbon export By A. J. R. Smith, S. Wotherspoon, et al. Read more Research Article  |  MICROBIOLOGY Highly multiplexed spatial transcriptomics in bacteria By Ari Sarfatis, Yuanyou Wang, et al. Read more Research Article  |  NEUROSCIENCE Identification of the subventricular tegmental nucleus as brainstem reward center By Krisztián Zichó, Boldizsár Zsolt Balog, et al. Read more Research Article  |  DIRECTED EVOLUTION Rapid in silico directed evolution by a protein language model with EVOLVEpro By Kaiyi Jiang, Zhaoqing Yan, et al. Read more Research Article  |  SOLAR CELLS Mechanically robust and stretchable organic solar cells plasticized by small-molecule acceptors By Zhenye Wang, Di Zhang, et al. Read more Research Article  |  ZEOLITES Atomic locations and adsorbate interactions of Al single and pair sites in H-ZSM-5 zeolite By Guangchao Li, Christopher Foo, et al. Read more Research Article  |  REPRODUCTION Systematic identification of Y-chromosome gene functions in mouse spermatogenesis By Jeremie Subrini, Wazeer Varsally, et al. Read more Research Article  |  METALLURGY Ductilization of 2.6-GPa alloys via short-range ordered interfaces and supranano precipitates By Yong-Qiang Yan, Wen-Hao Cha, et al. Read more Research Article  |  MATING SYSTEMS A single gene orchestrates androgen variation underlying male mating morphs in ruffs By Jasmine L. Loveland, Alex Zemella, et al. Read more Research Article  |  IMMUNOLOGY Affinity maturation of antibody responses is mediated by differential plasma cell proliferation By Andrew J. MacLean, Lachlan P. Deimel, et al. Read more Research Article  |  BIODIVERSITY Variable impacts of land-based climate mitigation on habitat area for vertebrate diversity By Jeffrey R. Smith, Evelyn M. Beaury, et al. Read more Research Article  |  MOLECULAR BIOLOGY Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin By Alexander Carver, Tai-Yuan Yu, et al. Read more Research Article  |  NONLINEAR PHONONICS Photo-induced chirality in a nonchiral crystal By Z. Zeng, M. Först, et al. Read more Errata Erratum for the Research Article “A chiral hydrogen atom abstraction catalyst for the enantioselective epimerization of meso-diols” by A. S. K. Lahdenperä et al. Read more Expression of Concern Editorial Expression of Concern By H. Holden Thorp Read more Careers Working Life A bite of expertise By Luke Childress Read more Association Affairs Association Affairs AAAS 2025 Annual Meeting Program Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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