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Brought to you by Science & PINS Prize for Neuromodulation VOLUME 387 | ISSUE 6735 | 14 FEB 2025 Editorial Editorial Breaking the silence By H. Holden Thorp, Meagan Phelan Read more News In Brief News at a glance Read more In Depth  |  Global Health U.S. aid freeze deals ‘tectonic’ blow to research By Catherine Offord, Jon Cohen, et al. Scientists decry ethical violations as trials worldwide are paused and workers laid off Read more In Depth  |  Science Policy Judge’s ruling leaves NIH’s move to abruptly slash grants in limbo By David Malakoff Universities, states, and research groups attack plan to cut billions in “indirect cost” payments as illegal and unwise Read more In Depth  |  Astrophysics Underwater light show heralds highest energy neutrino By Daniel Clery Event promises “new energy window on the universe” Read more In Depth  |  Workforce Retirement-age scientists just keep working By Katie Langin Desire to retain professional identity keeps Ph.D.s from stepping aside, survey shows Read more In Depth  |  Science Policy Congressional Republicans take aim at recent Biden regulations By Dan Charles Climate, ocean archaeology rules could be reversed Read more Feature Face readers By Christa Lesté-Lasserre Artificial intelligence is becoming better than humans at scanning animals’ faces for signs of stress and pain. Are more complex emotions next? Read more Insights Expert Voices Drylands under pressure: Science and solutions for global stability By Ismahane Elouafi Read more Perspective  |  Water Management Where does all the water go? By Taka’aki Taira, Roland Bürgmann Seismic noise measurements map out a deep groundwater recharge system Read more Perspective  |  Evolution Constrained roads to complex brains By Giacomo Gattoni, Maria Antonietta Tosches Neural development and brain circuit evolution converged in birds and mammals Read more Perspective  |  Neuroscience Understanding the desire for dessert By Sadaf Farooqi A neural circuit in mice mediates the preference for high-sugar food after a meal Read more Perspective  |  Hydrogen Production Thrifting iridium for hydrogen By Andrew D. Pendergast, Shannon W. Boettcher Anchoring catalysts on an engineered oxide support enables stable water electrolysis Read more Policy Forum  |  Conservation Time to fix the biodiversity leak By Andrew Balmford, Thomas S. Ball, et al. The risk that locally successful nature conservation may be shifting problems elsewhere can no longer be ignored Read more Books et al.  |  Science and Society Notes from the “politics factory” By H. Charles J. Godfray A former government science adviser dissects the complex meshing of science and policy Read more Books et al.  |  Research Misconduct A scientific field, misled By Carl Elliott Fraud undermines Alzheimer’s disease research Read more Letter India’s grasslands are not “wastelands” By Sutirtha Lahiri, Sushma Reddy Read more Letter Jordan’s electric vehicle growth drives trade-offs By Hussam J. Khasawneh, Hussam Hussein Read more Letter India’s ocean exploration undermines climate goals By Ayush Mistry Read more Research Research Highlights In Science Journals By Jesse Smith, Di Jiang, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Keith T. Smith, Sacha Vignieri, et al. Editors’ selections from the current scientific literature Read more Review  |  NEUROSCIENCE Neuroevolution insights into biological neural computation By Risto Miikkulainen Read more Research Article  |  IMMUNOLOGY KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection By Eric Fagerberg, John Attanasio, et al. Read more Research Article  |  ENZYMOLOGY Conformational ensembles reveal the origins of serine protease catalysis By Siyuan Du, Rachael C. Kretsch, et al. Read more Research Article  |  BRAIN EVOLUTION Evolutionary convergence of sensory circuits in the pallium of amniotes By Eneritz Rueda-Alaña, Rodrigo Senovilla-Ganzo, et al. Read more Research Article  |  BRAIN EVOLUTION Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium By Nikolai Hecker, Niklas Kempynck, et al. Read more Research Article  |  BRAIN EVOLUTION Developmental origins and evolution of pallial cell types and structures in birds By Bastienne Zaremba, Amir Fallahshahroudi, et al. Read more Research Article  |  CANCER RNA polymerase II at histone genes predicts outcome in human cancer By Steven Henikoff, Ye Zheng, et al. Read more Research Article  |  CATALYSIS Selective chemical looping combustion of acetylene in ethylene-rich streams By Matthew Jacob, Huy Nguyen, et al. Read more Research Article  |  NEUROSCIENCE Thalamic opioids from POMC satiety neurons switch on sugar appetite By Marielle Minère, Hannah Wilhelms, et al. Read more Research Article  |  GEOPHYSICS Depth-dependent seismic sensing of groundwater recovery from the atmospheric-river storms of 2023 By Shujuan Mao, William L. Ellsworth, et al. Read more Research Article  |  MARINE CONSERVATION Elephant seals as ecosystem sentinels for the northeast Pacific Ocean twilight zone By Roxanne S. Beltran, Allison R. Payne, et al. Read more Research Article  |  CATALYSIS Thermal catalytic reforming for hydrogen production with zero CO2 emission By Mi Peng, Yuzhen Ge, et al. Read more Research Article  |  MEMBRANES Engineering grain boundaries in monolayer molybdenum disulfide for efficient water-ion separation By Jie Shen, Areej Aljarb, et al. Read more Research Article  |  HYDROLOGY Variability of flowing stream network length across the US By Jeff P. Prancevic, Hansjörg Seybold, et al. Read more Research Article  |  QUANTUM MATERIALS Good plasmons in a bad metal By Francesco L. Ruta, Yinming Shao, et al. Read more Research Article  |  ELECTROCHEMISTRY Ultrastable supported oxygen evolution electrocatalyst formed by ripening-induced embedding By Wenjuan Shi, Tonghao Shen, et al. Read more Careers Working Life Rethinking success By Salahuddin Mohammed Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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