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Brought to you by Eppendorf & Science Prize for Neurobiology Now accepting entries for the US$ 25,000 Eppendorf & Science Prize for Neurobiology Deadline: June 15, 2025 Visit www.eppendorf.com/prize VOLUME 388 | ISSUE 6744 | 18 APR 2025 Editorial Editorial When state support for science fails By Antonio Lazcano Read more News In Brief News at a glance Read more In Depth  |  Trump Administration NIH bars Chinese scientists, others from databases By Richard Stone Trump administration escalates efforts to keep sensitive data from foreign adversaries Read more In Depth  |  Trump Administration NASA, NOAA face major climate science cuts By Paul Voosen National Climate Assessment is at risk, as are scores of other research programs Read more In Depth  |  Plant Biology Scientists identify structure that controls seed size By Erik Stokstad An overlooked “gate” governs nutrient transport to seeds and might one day boost agricultural harvests Read more In Depth  |  Evolution Cat domestication tied to ancient Egyptian cult By David Grimm Mass sacrifice of wildcats may have given rise to pet felines Read more In Depth  |  Higher Education After grant cuts, universities offer faculty a lifeline By Jeffrey Mervis “Bridge” programs are seen as temporary help but no substitute for sustained federal funding Read more In Depth  |  Biomedicine Companies seek second GLP-1 revolution—in pill form By Rachel Brazil Smaller, easier to make drug compounds could treat obesity and diabetes with fewer side effects Read more In Depth  |  Energy Research Lawsuit challenges DOE indirect costs cut By Jeffrey Mervis Judge blocked NIH from making a similar move Read more Feature Risky moves By Mitch Leslie Can blocking “jumping genes” treat diseases and aging? Read more Insights Expert Voices Designing and using robots for environmental sustainability By Aude G. Billard Read more Perspective  |  Geoscience Catching a glimpse of ancient Mars By Janice L. Bishop, Melissa D. Lane Exposed minerals hint at the evolution of geochemical conditions on early Mars Read more Perspective  |  Microbiology How bacteria subvert plant immunity By Frank C. Schroeder To prevent their detection, bacteria inhibit plant enzymes with a small molecule Read more Perspective  |  Neuroscience Dendritic arbors structure memories By Ayelén I. Groisman, Johannes J. Letzkus Synapses on different dendritic domains store distinct types of information Read more Perspective  |  Batteries Cracking the failure of lithium batteries By Jagjit Nanda, Sergiy Kalnaus Prolonged operation accumulates damage that is similar to fatigue in an electrode Read more Policy Forum  |  Sustainable Development Developing countries locked out of low-carbon technology trade By Praveena Bandara, Rebecca Ray, et al. More than 90% of all low-carbon technology trade is between high-income countries and China Read more Books et al.  |  Technology What we owe the present By Àlex Gómez-Marín A physicist issues an urgent call to deflate the world-shaping power of tech billionaires Read more Books et al.  |  Neuroscience Widening the autism spotlight By Meng-Chuan Lai Underrepresentation of girls and women in studies warps our understanding of the condition, argues a neuroscientist Read more Letter Disposal of anesthetics threatens ecosystems By Xin Liu, Ruolin Hou, et al. Read more Letter Prevent coastal seawater intrusion in China By Chao Liu, Ping Li, et al. Read more Letter Overcoming roadblocks to a global plastic pact By Farooq Shah, Wei Wu Read more Research Research Highlights In Science Journals By Bianca Lopez, Jake S. Yeston, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Keith T. Smith, Bianca Lopez, et al. Editors’ selections from the current scientific literature Read more Research Article  |  DEVELOPMENT Casz1 is required for both inner hair cell fate stabilization and outer hair cell survival By Yuwei Sun, Minhui Ren, et al. Read more Research Article  |  EVOLUTION Adaptation repeatedly uses complex structural genomic variation By Zachariah Gompert, Jeffrey L. Feder, et al. Read more Research Article  |  TISSUE IMAGING Deep-tissue transcriptomics and subcellular imaging at high spatial resolution By Valentina Gandin, Jun Kim, et al. Read more Research Article  |  STRUCTURAL BIOLOGY Structural basis for nucleolin recognition of MYC promoter G-quadruplex By Luying Chen, Jonathan Dickerhoff, et al. Read more Research Article  |  PLANT GENETICS The genetic architecture of cell type–specific cis regulation in maize By Alexandre P. Marand, Luguang Jiang, et al. Read more Research Article  |  ENZYME DESIGN Computational design of serine hydrolases By Anna Lauko, Samuel J. Pellock, et al. Read more Research Article  |  2D MATERIALS Perfect Coulomb drag in a dipolar excitonic insulator By Phuong X. Nguyen, Liguo Ma, et al. Read more Research Article  |  2D MATERIALS Perfect Coulomb drag and exciton transport in an excitonic insulator By Ruishi Qi, Andrew Y. Joe, et al. Read more Research Article  |  ORGANIC CHEMISTRY Asymmetric amination of alkyl radicals with two minimally different alkyl substituents By Yu-Feng Zhang, Biao Wang, et al. Read more Research Article  |  MARS GEOLOGY Carbonates identified by the Curiosity rover indicate a carbon cycle operated on ancient Mars By Benjamin M. Tutolo, Elisabeth M. Hausrath, et al. Read more Research Article  |  PLANT SCIENCE Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology By Nattapong Sanguankiattichai, Balakumaran Chandrasekar, et al. Read more Research Article  |  STRUCTURAL BIOLOGY Structure of human PINK1 at a mitochondrial TOM-VDAC array By Sylvie Callegari, Nicholas S. Kirk, et al. Read more Research Article  |  BATTERIES Fatigue of Li metal anode in solid-state batteries By Tengrui Wang, Bo Chen, et al. Read more Research Article  |  ENVIRONMENTAL SCIENCE Global soil pollution by toxic metals threatens agriculture and human health By Deyi Hou, Xiyue Jia, et al. Read more Research Article  |  NEUROSCIENCE Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learning By William J. Wright, Nathan G. Hedrick, et al. Read more Careers Working Life Not a ‘DEI hire’ By Troy Christopher Dildine Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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