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Brought to you by Science Podcasts VOLUME 389 | ISSUE 6757 | 17 JUL 2025 Editorial Editorial Science philanthropy faces a new reality By Adam Falk Read more News In Depth  |  Geochemistry Molecular fossils show how life survived Snowball Earth By Elise Cutts Overlooked rock samples from 640 million years ago record microbes clinging to life beneath frozen oceans Read more In Depth  |  Space Astronomers race to study third known interstellar interloper By Adam Mann World’s telescopes scrutinize inbound comet for clues on exoplanet formation Read more In Depth  |  Infectious Diseases NIH suspends alleged ‘gain-of-function’ studies By Jon Cohen, Jocelyn Kaiser Scientists told to stop pathogen work say agency’s criteria are mysterious and will stymie needed research Read more In Depth  |  Cosmology U.S. cancels hunt for signs of cosmic inflation By Adrian Cho Downsizing and high ratings did not save effort known as CMB-S4 Read more In Depth  |  Replication Crisis Fruit fly studies mostly defy concerns about irreproducibility By Cathleen O’Grady But large verification attempt finds some “suspicious” papers that fare much worse Read more Feature Haunted by sharks By Alexa Robles-Gil After a series of deadly shark attacks, the Indian Ocean island of Réunion became a hub of shark attack science Read more Commentary Expert Voices This is not the time to step back from diversity, equity, and inclusion By Agustín Fuentes Read more Perspective  |  Physics A new age of molecular chirality By Olga Smirnova Advanced optical approaches reshape the frontiers of chiral sensing Read more Perspective  |  Cell Biology Polyglycine proteins leave transfer RNAs unglued By Mridu Kapur, Susan L. Ackerman Disruption of transfer RNA processing may unite the pathogenesis of CGG repeat expansion disorders Read more Perspective  |  Computational Biology Disorder meets its match By Alan M. Moses, Julie D. Forman-Kay Designed protein pockets recognize intrinsically disordered protein regions Read more Perspective  |  Immunology RORing for oral tolerance By Cecilia Johansson An antigen-presenting cell subtype tames the immune response to food antigens in early life Read more Policy Forum  |  Climate Change The pursuit of 1.5°C endures as a legal and ethical imperative in a changing world By Joeri Rogelj, Lavanya Rajamani As the world nears 1.5°C of global warming, near-term emissions reductions and adequate adaptation become ever more important to ensure a safe and livable planet for present and future generations Read more Letter US disregards scientific consensus on race By Joseph L. Graves, Alan Goodman, et al. Read more Letter US should reject color-blind racial ideology By Tatiane Russo-Tait, Summer Blanco, et al. Read more Letter Combat disinformation about gender research By Arjee J. Restar, Kristi E. Gamarel, et al. Read more Research Research Highlights In Science Journals By Courtney Malo, Angela Hessler, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Sacha Vignieri, Ekeoma Uzogara, et al. Editors’ selections from the current scientific literature Read more Research Article  |  CELLULAR NEUROSCIENCE Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders By Jason Yang, Yunhan Xu, et al. Read more Research Article  |  MALARIA Vaccination to mitigate climate-driven disruptions to malaria control in Madagascar By Benjamin L. Rice, Estelle Raobson, et al. Read more Research Article  |  MOLECULAR BIOLOGY Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning By Upneet Kaur, Hao Wu, et al. Read more Research Article  |  PROTEIN DESIGN Design of intrinsically disordered region binding proteins By Kejia Wu, Hanlun Jiang, et al. Read more Research Article  |  PLANT SCIENCE Redox-regulated Aux/IAA multimerization modulates auxin responses By Dipan Roy, Poonam Mehra, et al. Read more Research Article  |  EARTHQUAKE ALERTS Global earthquake detection and warning using Android phones By Richard M. Allen, Alexei Barski, et al. Read more Research Article  |  NEUROIMMUNOLOGY Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense By Rocky M. Barilla, Clara Berard, et al. Read more Research Article  |  IMMUNOLOGY A wave of Thetis cells imparts tolerance to food antigens early in life By Vanja Cabric, Yollanda Franco Parisotto, et al. Read more Research Article  |  ORGANIC CHEMISTRY Skeletal editing of pyrrolidines by nitrogen-atom insertion By Jinghao Li, Pengcheng Tang, et al. Read more Research Article  |  NEUROSCIENCE Midline assembloids reveal regulators of human axon guidance By Massimo M. Onesto, Neal D. Amin, et al. Read more Research Article  |  MATERIALS SCIENCE Dome-celled aerogels with ultrahigh-temperature superelasticity over 2273 K By Kai Pang, Yuxing Xia, et al. Read more Research Article  |  ORGANIC CHEMISTRY Bridging the pyridine-pyridazine synthesis gap by skeletal editing By Mikus Puriņš, Hikaru Nakahara, et al. Read more Research Article  |  ELECTRONIC MATERIALS Two-dimensional indium selenide wafers for integrated electronics By Biao Qin, Jianfeng Jiang, et al. Read more Research Article  |  MICROBIOTA Controlled colonization of the human gut with a genetically engineered microbial therapeutic By Weston R. Whitaker, Zachary N. Russ, et al. Read more Research Article  |  MOLECULAR BIOLOGY ASB7 is a negative regulator of H3K9me3 homeostasis By Liwen Zhou, Zhenxuan Chen, et al. Read more Errata Erratum for the Research Article “Sunlight drives the abiotic formation of nitrous oxide in fresh and marine waters” by E. Leon-Palmero et al. Read more Careers Working Life Stigma did not kill my dream By Juan Carlos Cambronero-Heinrichs Read more Essay Essay  |  Artificial Intelligence AI to rewire life’s interactome: Structural foundation models help to elucidate and reprogram molecular biology By Zhuoran Qiao Structural foundation models help to elucidate and reprogram molecular biology Read more Essay  |  Artificial Intelligence Unraveling the emergent chorus of the mind: Machine learning reveals how a hidden neural code orchestrates diverse emotion states By Aditya Nair Machine learning reveals how a hidden neural code orchestrates diverse emotion states Read more Essay  |  Artificial Intelligence Mapping the global coastal ocean with AI: Artificial neural networks can help better constrain the global carbon cycle in shallow seas By Alizée Roobaert Artificial neural networks can help better constrain the global carbon cycle in shallow seas Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. 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