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Brought to you by AI and Mental Health Conference 2025 VOLUME 389 | ISSUE 6761 | 14 AUG 2025 Editorial Editorial Scientists’ role in defending democracy By Gretchen Goldman, Erica Chenoweth Read more News In Depth  |  Infectious Diseases NIH weighs controversial overhaul of HIV budget By Jon Cohen Scientists worry $1 billion push for “implementation science” will harm basic research Read more In Depth  |  Medical Physics Twist on PET unlocks hidden signals By Zack Savitsky Overlooked emissions from exotic positronium atoms open unexpected window for diagnosing cancer and other diseases Read more In Depth  |  Physics Correction in Science rekindles debate over Microsoft’s quantum computing research By Adam Mann Disputes over elusive Majorana particles—the hoped-for key to robust quantum chips—continue to divide the field Read more In Depth  |  Policy Europe eyes civilian science funding for defense research By Elise Cutts Worried about regional security, the EU wants to allow major grants to fund “dual-use” projects for the first time Read more In Depth  |  Science Policy Trump moves to politicize decisions on science grants By Jeffrey Mervis Researchers say plan would enable political operatives to overrule peer reviewers Read more Feature Beyond lab animals By Sara Reardon With a boost from the Trump administration, organ chips, AI, and other technologies bid to replace animals for drug and chemical testing Read more Commentary Expert Voices Robots that share our spaces require proprioception and a sense of touch By Aude G. Billard Read more Perspective  |  Plant Science The scent of a crowd By Niklas Schandry, Claude Becker Maize plants recruit immunity-modulating soil microbes in response to high-density planting Read more Perspective  |  Physics Seeing with atoms By Bodil Holst A beam of neutral atoms penetrates a solid material to probe its properties Read more Perspective  |  Cancer The ins and outs of circulating DNA By W. H. Adrian Tsui, Y. M. Dennis Lo DNA sequestered in circulating platelets could inform early tumor diagnosis Read more Perspective  |  Immunology Setting the table for immune tolerance By Michael Silverman, Kathryn Knoop Interaction between breast milk antibodies and gut microbes shape immune responses during weaning Read more Perspective  |  Microbiology Mitochondria hoard folate to starve a parasite By Anu Suomalainen, Joni Nikkanen Metabolic immunity contributes to cells’ defenses against Toxoplasma gondii Read more Policy Forum  |  Agriculture Climate-smart biofuel policy as a pathway to decarbonize agriculture By Madhu Khanna, Bruno Basso, et al. A policy that relies on farm-specific carbon-intensity scores can promote climate-smart agricultural practices. Read more Books et al.  |  Professional Development Leading a lab, and all it entails By Jonathan Wai A chemist offers actionable leadership advice to principal investigators Read more Books et al.  |  Scientific Integrity The Sisyphean quest for scientific certainty By Sorin M. S. Krammer An epidemiologist calls for humility and triangulation to converge on truth Read more Letter Risks of ending US science-policy training By Scott Glaberman, Cynthia Wei Read more Letter Editor’s Note By H. Holden Thorp Read more Letter Addressing Southeast Asia’s plastic pollution By Tu Xayachak, Nawshad Haque, et al. Read more Letter West Philippine Sea dispute threatens sea life By Adrian A. Mabalay Read more Research Research Highlights In Science Journals By Corinne Simonti, Jake S. Yeston, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Corinne Simonti, Ekeoma Uzogara, et al. Editors’ selections from the current scientific literature Read more Research Article  |  IMMUNOLOGY Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens By Meera K. Shenoy, Diane M. Rico, et al. Read more Research Article  |  PLATELETS Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA By Lauren Murphy, Jeanne Inchauspé, et al. Read more Research Article  |  CELL BIOLOGY Mitochondria protect against an intracellular pathogen by restricting access to folate By Tânia Catarina Medeiros, Jana Ovciarikova, et al. Read more Research Article  |  OPTICAL MATERIALS Hierarchical chiral supramolecular assemblies with strong and invertible chiroptical properties By Minju Kim, Mingyue Zhang, et al. Read more Research Article  |  PLANT COMMUNICATION Linalool-triggered plant-soil feedback drives defense adaptation in dense maize plantings By Dongsheng Guo, Zilin Liu, et al. Read more Research Article  |  PROTEIN SIMULATIONS Scalable emulation of protein equilibrium ensembles with generative deep learning By Sarah Lewis, Tim Hempel, et al. Read more Research Article  |  ANCIENT PROTEINS The proteome of the late Middle Pleistocene Harbin individual By Qiaomei Fu, Fan Bai, et al. Read more Research Article  |  CARBON ALLOTROPES Solution-phase stabilization of a cyclocarbon by catenane formation By Yueze Gao, Prakhar Gupta, et al. Read more Research Article  |  METHANOGENESIS Modulation of methyl–coenzyme M reductase expression alters the isotopic composition of microbial methane By Jonathan Gropp, Markus Bill, et al. Read more Research Article  |  MANY-BODY DYNAMICS Observation of many-body dynamical localization By Yanliang Guo, Sudipta Dhar, et al. Read more Research Article  |  FUNGAL GENETICS Early germline sequestration in a basidiomycete fungus By Markus Hiltunen Thorén, Boel Olsson, et al. Read more Research Article  |  STRUCTURAL METHODS Diffraction of helium and hydrogen atoms through single-layer graphene By Carina Kanitz, Jakob Bühler, et al. Read more Research Article  |  NUCLEAR FUSION Predicting fusion ignition at the National Ignition Facility with physics-informed deep learning By Brian K. Spears, Scott Brandon, et al. Read more Research Article  |  BIOCATALYSIS Artificial farnesol epoxidase enables a concise synthesis of meroterpenoids By Jinxin Wang, Yunpeng Yin, et al. Read more Research Article  |  2D MATERIALS Strong interactions and isospin symmetry breaking in a supermoiré lattice By Yonglong Xie, Andrew T. Pierce, et al. Read more Research Article  |  BIOCATALYSIS Enantioconvergent benzylic C(sp3)‒N coupling with a copper-substituted nonheme enzyme By Xuzhong Shen, Xiahe Chen, et al. Read more Research Article  |  EVOLUTIONARY BIOLOGY Cross-species implementation of an innate courtship behavior by manipulation of the sex-determinant gene By Ryoya Tanaka, Yusuke Hara, et al. Read more Errata Erratum for the Research Article “Flux-induced topological superconductivity in full-shell nanowires” by S. Vaitiekėnas et al. Read more Errata Erratum for the Research Article “Improving metrology with quantum scrambling” by Z. Li et al. Read more Careers Working Life How I learned to ride By Ehsan Hamzehpoor Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. 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