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Brought to you by Science Webinars VOLUME 389 | ISSUE 6762 | 21 AUG 2025 Editorial Editorial Rewiring science diplomacy By Vaughan C. Turekian, Peter Gluckman Read more News In Depth  |  Conservation Biology As salmon in Alaska plummet, scientists suspect a parasite By Warren Cornwall Chinook in the Yukon River appear to be particularly vulnerable—and warming waters may be abetting the infection Read more In Depth  |  Human Evolution Denisovans, Neanderthals gave Indigenous Americans key mucus gene By Michael Price Genetic variant might have given the first Americans a sticky shield against new germs Read more In Depth  |  Social Science Don’t blame the algorithms for online polarization By Hannah Richter In tests with virtual social media users, echo chambers and extreme voices always emerged Read more In Depth  |  Biology New antibiotics from the third branch of life? By Robert F. Service Archaea appear to wield a host of bacteria-killing compounds Read more In Depth  |  Astrophysics Astronomers set biggest traps ever for messengers from cosmic accelerators By Daniel Clery Vast arrays of radio antennas could trace neutrinos back to supernovae and black holes Read more In Depth  |  Animal Research Faced with ‘impossible’ workload, USDA struggles to oversee lab animal welfare By David Grimm Shrinking staff and other handicaps threaten enforcement of the Animal Welfare Act Read more Feature Probing the pain By Meredith Wadman Katie Burns is helping uncover the role of the immune system in endometriosis—while managing her own disease Read more Commentary Expert Voices Disability and AI: Much more than assistive technologies By Jackie Leach Scully Read more Perspective  |  Neuroscience A shared circuit might link depression and anxiety By Michael T. Treadway Loss of motivation and heightened sensitivity to threat are driven by a network of overlapping brain regions Read more Perspective  |  Bioinspired Robots Ripple bug robots demonstrate interfacial intelligence By Cameron A. Aubin Insect and robot appendages are autonomously controlled by the air-water interface Read more Perspective  |  Physics Outshining molecular disorder with light By Minjung Son Experiments quantify an important criterion for polariton-mediated energy transport Read more Perspective  |  Cell Biology A protein tunnel helps stressed lysosomes swell By Jennifer Lippincott-Schwartz The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand Read more Policy Forum  |  Biobanking Disrupting the biospecimen “treasure trove”: Practice, precedent, and future directions By Leslie E. Wolf, Samantha Kench, et al. Decentralized biobanking can reconnect individuals to their specimens, democratizing data ownership Read more Books et al.  |  Biology Mutualism—here, there, and everywhere By Dale Jamieson A biologist finds wisdom in nature’s reciprocal partnerships Read more Books et al.  |  Paleoanthropology Discovering Denisova By Brenna R. Hassett A pair of authors invite readers to get to know the elusive archaic human Read more Letter Pakistan’s reptiles need protection By Muhammad Ishfaq Read more Letter Yarmouk Treaty could ease Jordan’s water crisis By Hussam Hussein Read more Letter Brazilian policy weakens shark conservation By Gustavo F. de Carvalho-Souza, José Truda Palazzo Read more Reviews Review  |  DRUG DEVELOPMENT Load and lock: An emerging class of therapeutics that influence macromolecular dissociation By Raymond J. Deshaies, Patrick Ryan Potts Read more Research Research Highlights In Science Journals By Sacha Vignieri, Jelena Stajic, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Madeleine Seale, Stella M. Hurtley, et al. Editors’ selections from the current scientific literature Read more Research Article  |  ARCHAIC HOMININS The MUC19 gene: An evolutionary history of recurrent introgression and natural selection By Fernando A. Villanea, David Peede, et al. Read more Research Article  |  SINGLE-CELL ANALYSIS Stereo-cell: Spatial enhanced-resolution single-cell sequencing with high-density DNA nanoball-patterned arrays By Sha Liao, Xiaoxi Zhou, et al. Read more Research Article  |  EVOLUTION Recent evolution of the developing human intestine affects metabolic and barrier functions By Qianhui Yu, Umut Kilik, et al. Read more Research Article  |  BACTERIAL IMMUNITY Disassembly activates Retron-Septu for antiphage defense By Chen Wang, Anthony D. Rish, et al. Read more Research Article  |  CELL BIOLOGY LYVAC/PDZD8 is a lysosomal vacuolator By Haoxiang Yang, Jinrui Xun, et al. Read more Research Article  |  QUANTUM SIMULATION Universal coarsening in a homogeneous two-dimensional Bose gas By Martin Gazo, Andrey Karailiev, et al. Read more Research Article  |  PHOTONICS Ultracompact on-chip spectral shaping using pixelated nano-opto-electro-mechanical gratings By Weixin Liu, Siyu Xu, et al. Read more Research Article  |  BIOMIMICRY Ultrafast elastocapillary fans control agile maneuvering in ripple bugs and robots By Victor M. Ortega-Jimenez, Dongjin Kim, et al. Read more Research Article  |  LIGHT POLLUTION Light pollution prolongs avian activity By Brent S. Pease, Neil A. Gilbert Read more Research Article  |  QUANTUM MATTER The quantum metric of electrons with spin-momentum locking By Giacomo Sala, Maria Teresa Mercaldo, et al. Read more Research Article  |  GEOGRAPHY Increasing global human exposure to wildland fires despite declining burned area By Seyd Teymoor Seydi, John T. Abatzoglou, et al. Read more Research Article  |  SPINTRONICS Electrical coherent driving of chiral antiferromagnet By Yutaro Takeuchi, Yuma Sato, et al. Read more Research Article  |  CONSERVATION GENETICS Fitness benefits of genetic rescue despite chromosomal differences in an endangered pocket mouse By Aryn P. Wilder, Debra M. Shier, et al. Read more Research Article  |  NEUROSCIENCE Dysfunction in primate dorsolateral prefrontal area 46 affects motivation and anxiety By Christian M. Wood, Rana Banai Tizkar, et al. Read more Research Article  |  CHEMICAL PHYSICS Overcoming energy disorder for cavity-enabled energy transfer in vibrational polaritons By Guoxin Yin, Tianlin Liu, et al. Read more Careers Working Life Authorship, erased By Hari Ram C. R. 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