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Brought to you by Science Webinars VOLUME 389 | ISSUE 6767 | 25 SEP 2025 Editorial Editorial The EPA’s shaken foundation By H. Christopher Frey Read more News In Depth  |  Climate Change Buried salt is abetting Arctic thaw By Tim Appenzeller Ancient layers of saline permafrost are melting below zero, deepening lakes and weakening coasts Read more In Depth  |  Artificial Intelligence Researchers customize AI tools at global ‘hackathon’ By Zack Savitsky Large language models are tweaked and tuned to accelerate research in materials science and chemistry Read more In Depth  |  Scientific Community Science’s grim mood colors lighthearted Ig Nobel prizes By Hannah Richter Some winning researchers decline to attend celebration, citing politics and visa restrictions Read more In Depth  |  Artificial Intelligence Ethicists flirt with AI for reviewing human research By Celina Zhao Large language models could help reduce backlog of study proposals, but critics are wary of entrusting ethics to machines Read more In Depth  |  Biomedicine Autism initiative embraces little-tested vitamin as a treatment By Gretchen Vogel FDA to approve leucovorin despite questions about whom it might help Read more In Depth  |  Nuclear Physics The cosmic time machine on Long Island winds down By Adrian Cho The Relativistic Heavy Ion Collider re-created the Big Bang. The torch now passes to Europe Read more Feature NSF held captive By Jeffrey Mervis Trump directives have undermined a 75-year history of independence and threaten the agency’s vaunted track record for excellence Read more Commentary Perspective  |  Ecology Gardening strategies of termite farmers By Aryel C. Goes, Rachelle M. M. Adams Termites use microbe-infused soil to protect a fungal symbiont Read more Perspective  |  Hypothesis Understanding avian influenza mortality By John M. Drake Three theories could explain why the North American H5N1 epidemic has not been more deadly Read more Perspective  |  Genetics An inheritance of long life By K. Adam Bohnert Parental lysosomes modify epigenetic signaling to influence offspring life span Read more Perspective  |  Seismology Earthquakes in the blind spot By Emily E. Brodsky, Sergio Ruiz Closing offshore monitoring gaps is essential to prepare for the next large earthquake Read more Books et al.  |  Longevity The vitality of old age By Michael A. Goldman An anthropologist confronts aging myths and rejects notions of elder obsolescence Read more Books et al.  |  Political Science Why democracies die and what to do next By Rachel Beatty Riedl A political scientist offers strategies to combat democratic erosion Read more Books et al.  |  Podcast What to Expect When You're Dead: An Ancient Tour of Death and the Afterlife Read more Letter Corporate tourism threatens protected areas By Christopher J. O’Bryan, James R. Allan, et al. Read more Letter  |  Outside the Tower Op-eds connect scientists and communities By Miles J. Arnett Read more Letter Tourism puts Zanzibari reserve at a crossroads By Tim Caro, Giacomo Baldesi, et al. Read more Analysis Policy Article  |  Science Funding What if NIH had been 40% smaller? By Pierre Azoulay, Matthew Clancy, et al. Replaying history with less NIH funding shows widespread impacts on drug-linked research Read more Reviews Review  |  MEDICAL TECHNOLOGY From reactive to proactive: Continuous protein monitoring for preventive health care By Jane M. Donnelly, Ryan A. Neff, et al. Read more Research Research Highlights In Science Journals By Yury Suleymanov, Angela Hessler, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Bianca Lopez, Sarah Lemprière, et al. Editors’ selections from the current scientific literature Read more Research Article  |  PALEOCLIMATE Instability in the geological regulation of Earth’s climate By Dominik Hülse, Andy Ridgwell Read more Research Article  |  MOLECULAR BIOLOGY Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing By Changwei Shao, Yajing Hao, et al. Read more Research Article  |  SYSTEMS BIOLOGY Dual transposon sequencing profiles the genetic interaction landscape in bacteria By Justin J. Zik, Morgan N. Price, et al. Read more Research Article  |  BIOCATALYSIS Diversity-oriented photobiocatalytic synthesis via stereoselective three-component radical coupling By Chen Zhang, Jun Zhou, et al. Read more Research Article  |  CONSERVATION BIOLOGY Critical habitat thresholds for effective pollinator conservation in agricultural landscapes By Gabriella A. Bishop, David Kleijn, et al. Read more Research Article  |  ANTHROPOLOGY The phylogenetic position of the Yunxian cranium elucidates the origin of Homo longi and the Denisovans By Xiaobo Feng, Qiyu Yin, et al. Read more Research Article  |  CRITICAL MINERALS By-product recovery from US metal mines could reduce import reliance for critical minerals By Elizabeth A. Holley, Karlie M. Hadden, et al. Read more Research Article  |  QUANTUM PROCESSING Quantum learning advantage on a scalable photonic platform By Zheng-Hao Liu, Romain Brunel, et al. Read more Research Article  |  PREDATION AVOIDANCE Global selection on insect antipredator coloration By Iliana Medina, Alice Exnerová, et al. Read more Research Article  |  SEMICONDUCTORS Identification of short-range ordering motifs in semiconductors By Lilian M. Vogl, Shunda Chen, et al. Read more Research Article  |  BACTERIAL IMMUNITY Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity By Douglas R. Wassarman, Patrick Pfaff, et al. Read more Research Article  |  AGING Lysosomes signal through the epigenome to regulate longevity across generations By Qinghao Zhang, Weiwei Dang, et al. Read more Research Article  |  EARTHQUAKE DYNAMICS Fiber-imaged supershear dynamics in the 2024 Mw 7 Mendocino Fault earthquake By James Atterholt, Jeffrey J. McGuire, et al. Read more Research Article  |  NATURAL HISTORY Fungus-farming termites can protect their crop by confining weeds with fungistatic soil boluses By Aanchal Panchal, Ruchira Sen, et al. Read more Errata Erratum for the Report “Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways” by A. Weinberg et al. Read more Retraction Retraction By Phan Tan Toi, Hyun Jae Jang, et al. Read more Careers Working Life Hope, rediscovered By Easton R. White Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. 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