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Brought to you by The 5th Innovation Forum on Intelligent Computing VOLUME 390 | ISSUE 6768 | 2 OCT 2025 Editorial Editorial UN politics won’t deliver an ambitious plastics treaty By Peter Dauvergne, Jen Iris Allan Read more News In Depth  |  Paleoanthropology Dutch government agrees to return Java Man, thousands of other fossils to Indonesia By Martin Enserink Indonesian scientists celebrate repatriation of fossil collection from the colonial era Read more In Depth  |  Influenza Canada’s Supreme Court will decide fate of ostrich flock hit by bird flu By Jon Cohen Farmers and supporters—including RFK Jr. and Dr. Oz—urge government to spare birds, citing research potential Read more In Depth  |  Neuroscience Ambitious collaboration will map primate brains—including ours—in unprecedented detail By Richard Stone 25-year plan will tap brain-mapping prowess in China and two dozen other countries Read more In Depth  |  Environment AI map reveals vast scope of ‘ghost forests’ along east coast of U.S. By James Dinneen Machine learning method counts nearly 12 million dead trees, many likely killed by rising seas Read more In Depth  |  Biomedicine In a first, a gene therapy seems to slow Huntington disease By Jocelyn Kaiser Small study suggests uniQure drug could be first successful treatment for devastating brain disorder Read more In Depth  |  Anthropology New museum bolsters China’s controversial claim to Pacific languages By Marcel Hobma Nationalist narrative holds that Austronesian language and culture originated in China, not Taiwan Read more Feature Pharma’s hot zone By Robert F. Service A new generation of radiotherapies promises a more targeted attack on cancer Read more Commentary Expert Voices The paradox of AI accelerationism and the promise of public interest AI By Chinasa T. Okolo Read more Perspective  |  Plant Science Getting to the root of the pattern By Ekaterina Kozaeva, Jennifer A. N. Brophy Root barriers and metabolite leakage shape microbial colonization of plants Read more Perspective  |  Neuroscience Hidden networks in the brain By Dimitri Budinger, Michael T. Heneka Dendritic nanotubes extend brain connectivity beyond synapses Read more Perspective  |  Batteries Battery charging goes quantum By Robert E. Warburton Lithium-ion batteries charge through coupled classical and quantum-mechanical processes Read more Perspective  |  Oceanography Upwelling that lasted millions of years By Yair Rosenthal, Anya V. Hess Sedimentary records hint at how the equatorial Pacific may evolve in a future warm climate Read more Policy Forum  |  Wildfire Wildfire management at a crossroads: Mitigation and prevention or response and recovery? By Robert Gray, Robin Gregory, et al. As direct and indirect costs of fires continue to grow, so too might motivation to invest more heavily in mitigation Read more Books et al.  |  Medicine On prosthetics, printed organs, and pig hearts By Christopher Kemp A veteran science writer returns with a whirlwind tour of body modification and repair Read more Books et al.  |  Science Lives A computer scientist’s technological gamble By Jonathan Wai The inventor of the World Wide Web reflects on his life-altering creation Read more Letter  |  NextGen Voices National assessments in verse By Rida Ismail, Ana Brenda Guzovsky, et al. Read more Research Research Highlights In Science Journals By Jesse Smith, Corinne Simonti, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Yevgeniya Nusinovich, L. Bryan Ray, et al. Editors’ selections from the current scientific literature Read more Research Article  |  BATTERIES Lithium-ion intercalation by coupled ion-electron transfer By Yirui Zhang, Dimitrios Fraggedakis, et al. Read more Research Article  |  MOLECULAR BIOLOGY ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes By Camille Moore, Emily Wong, et al. Read more Research Article  |  MOLECULAR BIOLOGY A comprehensive genetic catalog of human double-strand break repair By Ernesto López de Alba, Israel Salguero, et al. Read more Research Article  |  NEUROSCIENCE Intercellular communication in the brain through a dendritic nanotubular network By Minhyeok Chang, Sarah Krüssel, et al. Read more Research Article  |  PALEOCEANOGRAPHY Persistent eastern equatorial Pacific Ocean upwelling since the warm Pliocene By Patrick A. Rafter, Jesse R. Farmer, et al. Read more Research Article  |  SIGNAL TRANSDUCTION GCN1 couples GCN2 to ribosomal state to initiate amino acid response pathway signaling By Changqian Zhou, Miao Zhang, et al. Read more Research Article  |  PLANT SCIENCE Localized glutamine leakage drives the spatial structure of root microbial colonization By Huei-Hsuan Tsai, Yuanjie Tang, et al. Read more Research Article  |  ANCIENT DNA Columbian mammoth mitogenomes from Mexico uncover the species’ complex evolutionary history By Eduardo Arrieta-Donato, Ángeles Tavares-Guzmán, et al. Read more Research Article  |  WILDFIRES Climate-linked escalation of societally disastrous wildfires By Calum X. Cunningham, John T. Abatzoglou, et al. Read more Research Article  |  EVOLUTION Ancient alleles drive contemporary climate adaptation in an alpine plant By Simone Fior, Hirzi Luqman, et al. Read more Research Article  |  FISH EVOLUTION Marine origins and freshwater radiations of the otophysan fishes By Juan Liu, Donald B. Brinkman, et al. Read more Research Article  |  VOLCANOLOGY A clearer view of the current phase of unrest at Campi Flegrei caldera By Xing Tan, Anna Tramelli, et al. Read more Research Article  |  QUANTUM OPTICS A high-resolution molecular spin-photon interface at telecommunication wavelengths By Leah R. Weiss, Grant T. Smith, et al. Read more Research Article  |  BIOSECURITY Strengthening nucleic acid biosecurity screening against generative protein design tools By Bruce J. Wittmann, Tessa Alexanian, et al. Read more Research Article  |  PLASTIC UPCYCLING Integrated low-temperature PVC and polyolefin upgrading By Wei Zhang, Boda Yang, et al. Read more Research Article  |  NANOMATERIALS Two-dimensional diboron trioxide crystal composed by boroxol groups By T. Zio, M Dirindin, et al. 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