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Brought to you by Science Webinars VOLUME 390 | ISSUE 6774 | 13 NOV 2025 Editorial Editorial Avoiding the climate “ambition trap” By Navroz K. Dubash Read more News In Depth  |  Marine Science Australia’s toxic algal bloom has a surprise culprit By Erik Stokstad A relatively unknown species is producing a notorious neurotoxin, devastating sea life Read more In Depth  |  Environment Sand mining threatens one of Asia’s largest lakes By Dennis Normile Cambodia’s Tonlé Sap supports important fisheries and wildlife Read more In Depth  |  Science Funding Texas dementia researchers cheer $3 billion initiative By Jennie Erin Smith Voters approve new effort modeled after the state’s long-running cancer research institute Read more In Depth  |  U.S. Policy Sweeping ban on Chinese collaborations proposed By Jeffrey Mervis Researchers speak out against proposal that would bar most ties Read more In Depth  |  Scientific Community James Watson: A flawed titan of science By Jon Cohen Science historian Nathaniel Comfort reflects on the “most famous scientist of the 20th century, and the most infamous of the 21st” Read more In Depth  |  Biomedicine Idea that gut microbes contribute to autism draws fire By Cathleen O’Grady Amid growing investments in the field, a new paper argues it rests on shaky foundations Read more Feature The pandemic next time By Jon Cohen How President Donald Trump’s administration has undermined efforts to develop vaccines and drugs for the next viral scourge Read more Commentary Expert Voices After science By James Evans, Eamon Duede Read more Perspective  |  Anthropology Dog domestication, from the fierce to the feisty By Melanie Fillios Quantitative analysis of canid skulls points to an earlier origin of dog diversity Read more Perspective  |  Evolution Sponging away phylogenomic incongruence By Peter O. Mulhair, Anthony K. Redmond Genes with strong and consistent signals favor sponges as humans’ most distant animal relatives Read more Perspective  |  Batteries A balancing act of ions By Mingliang Liu, Ali Coskun Tailoring ion movements at the electrode-electrolyte interface enables a fast-charging lithium-ion battery Read more Perspective  |  Synthetic Biology Programmable DNA insertion in native gut bacteria By Amandine Maire, David Bikard A gene-editing approach enables modification of bacteria within the mouse gut Read more Policy Forum  |  Environmental Regulation Include a mixture allocation factor to improve EU chemical risk management By Thomas Backhaus, Martin Scholze, et al. Revision of the REACH chemical regulation should enable more realistic understanding and management Read more Books et al.  |  Neuroscience Meditations on memory By Gisella Vetere A neuroscientist presents an intimate portrait of engram research Read more Books et al.  |  Science Lives Francis Crick’s life and legacy By Adrian Woolfson A new biography offers a definitive account of the DNA decoder Read more Letter Align wildfire prevention with conservation By Miguel Ángel Gómez-Serrano Read more Letter Water aid requires global groundwater safety By Yaqiang Wei Read more Letter Urban impact of rare earth elements By Jin Ma, Fengchang Wu Read more Research Research Highlights In Science Journals By Marc Lavine, Keith T. Smith, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By L. Bryan Ray, Ekeoma Uzogara, et al. Editors’ selections from the current scientific literature Read more Research Article  |  NEUROIMMUNOLOGY Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration By Yulin Li, Zhiguo Li, et al. Read more Research Article  |  CARDIOLOGY Flexible nanoelectronics reveal arrhythmogenesis in transplanted human cardiomyocytes By Junya Aoyama, Ren Liu, et al. Read more Research Article  |  SYNTHETIC BIOLOGY Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases By Diego Rivera Gelsinger, Carlotta Ronda, et al. Read more Research Article  |  PLANT BIOTECHNOLOGY Engineered geminivirus replicons enable rapid in planta directed evolution By Haocheng Zhu, Xu Qin, et al. Read more Research Article  |  REPRODUCTION PIEZO channels link mechanical forces to uterine contractions in parturition By Yunxiao Zhang, Sejal A. Kini, et al. Read more Research Article  |  PLANT EPIGENETICS Transposable elements are vectors of recurrent transgenerational epigenetic inheritance By Pierre Baduel, Louna De Oliveira, et al. Read more Research Article  |  CANCER IMMUNOLOGY Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity By Bowen Xie, Bowen Yuan, et al. Read more Research Article  |  BROWN DWARFS Observation of undepleted phosphine in the atmosphere of a low-temperature brown dwarf By Adam J. Burgasser, Eileen C. Gonzales, et al. Read more Research Article  |  SIGNAL TRANSDUCTION Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2 By Joseph E. Klebba, Nilotpal Roy, et al. Read more Research Article  |  MEDICAL ROBOTICS Clinically ready magnetic microrobots for targeted therapies By Fabian C. Landers, Lukas Hertle, et al. Read more Research Article  |  OPTOELECTRONICS Layer-by-layer epitaxial growth of perovskite heterostructures with tunable band offsets By Yang Lu, Young-Kwang Jung, et al. Read more Research Article  |  PALEONTOLOGY Earliest oceanic tetrapod ecosystem reveals rapid complexification of Triassic marine communities By Aubrey J. Roberts, Maciej Rucinski, et al. Read more Research Article  |  IMMUNOLOGY Branched actin networks mediate macrophage-dependent host-microbiota homeostasis By Luiz Ricardo C. Vasconcellos, Shaina Chor Mei Huang, et al. Read more Research Article  |  DOG DOMESTICATION Genomic evidence for the Holocene codispersal of dogs and humans across Eastern Eurasia By Shao-Jie Zhang, Lachie Scarsbrook, et al. Read more Research Article  |  DOG DOMESTICATION The emergence and diversification of dog morphology By Allowen Evin, Carly Ameen, et al. Read more Research Article  |  ELECTROCHEMISTRY Electrolytes that reduce electro-osmotic drag improve fast charging of lithium-ion batteries By Chang-Xin Zhao, Zeyi Wang, et al. Read more Research Article  |  PHYLOGENETICS Integrative phylogenomics positions sponges at the root of the animal tree By Jacob L. Steenwyk, Nicole King Read more Errata Erratum for the Report “FCHo Proteins Are Nucleators of Clathrin-Mediated Endocytosis” by W. M. Henne et al. Read more Errata Erratum for the Research Article “Systematic discovery and engineering of synthetic immune receptors in plants” by B. P. M. Ngou et al. Read more Careers Working Life My family’s sacrifice sustains me By Uzoma Ajugwe Read more Essay Essay  |  Molecular Medicine The missing piece: Solving the 50-year puzzle of BMP synthesis in neurodegeneration By Uche Medoh Solving the 50-year puzzle of BMP synthesis in neurodegeneration Read more Essay  |  Cell & Molecular Biology Oncogenes out of context: Cancer genes break free from the regulatory constraints of chromosomes By King L. Hung Cancer genes break free from the regulatory constraints of chromosomes Read more Essay  |  Ecology & Environment Balancing between evolutionary rescue and extinction: The adaptive potential of reef-building corals in a warming world By Liam Lachs The adaptive potential of reef-building corals in a warming world Read more Essay  |  Genomics, Proteomics, & Systems Biology Nucleotides on the frontline: Nucleotide-centric defense systems reveal a core principle in bacterial antiviral immunity By Nitzan Tal Nucleotide-centric defense systems reveal a core principle in bacterial antiviral immunity Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. 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