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Brought to you by Messe München VOLUME 391 | ISSUE 6782 | 15 JAN 2026 Editorial Editorial The High Seas Treaty, at last By Kirsten Grorud-Colvert, Jenna Sullivan-Stack Read more News In Depth  |  Infectious Diseases Scientists reject call to retest childhood vaccines By Jon Cohen “Gold standard” trials advocated by the Trump administration are unethical and unnecessary, critics say Read more In Depth  |  Genomics Cellular ‘vaults’ deployed to spy on gene activity By John Travis Enigmatic protein shells can be engineered to capture messenger RNA made by cells over the course of a week Read more In Depth  |  Ecology Low doses of insecticide speed fish aging and death By Erik Stokstad Harms of chlorpyrifos emerge in polluted lakes and laboratory aquarium tanks Read more In Depth  |  Climate Change Arctic’s ‘last ice area’ is on thin ice By Rachel Berkowitz Mission to Canada’s Queen Elizabeth Islands reveals signs of weakness in a sea ice haven Read more In Depth  |  Astronomy Ex–Google CEO funds private space telescope bigger than Hubble By Daniel Clery Schmidt Sciences invests in orbiting observatory and three ground-based instruments Read more Feature A difficult rebirth By Sofia Quaglia Scientists are ramping up an ambitious project to reverse centuries of ecological destruction on a Galápagos island Read more Commentary Expert Voices The mirage of AI deregulation By Alondra Nelson Read more Perspective  |  Paleontology Not a big baby By Andrew A. Farke Multipronged approaches resolve the debate about the Nanotyrannus fossil species Read more Perspective  |  Glaciology Uncovering Antarctica’s ice-draped landscape By Duncan A. Young The mesoscale topographical variability beneath a continent-scale ice sheet is revealed Read more Perspective  |  Metabolism Blood vessels under pressure By Mandy O. J. Grootaert, Aernout Luttun A protein in perivascular fat cells protects mice against hypertension Read more Perspective  |  Materials Science Robust perovskite nanocrystal emitters By Keyu Wei, Mingjian Yuan Hierarchical shells stabilize soft and labile metal halide perovskite surfaces for screen displays Read more Perspective  |  Evolution A new cell type drove human brain complexity By Antonela Bonafina, Laurent Nguyen How did the human brain acquire a vast repertoire of interneurons? Read more Policy Forum  |  Sustainable Development A theory of change approach to enhance the post-2030 sustainable development agenda By Cameron Allen, Shirin Malekpour, et al. A better approach is needed to assess potential impact and feasibility of proposals Read more Books et al.  |  Plant Science The branching legacies of America’s past By Maria Pinto Plants serve as witnesses to the country’s history in a primer that celebrates Black botanical knowledge Read more Books et al.  |  Science and Society Careful science is valuable, regardless of results By Byron Hyde Scientists should be celebrated for more than just flashy findings, argues a philosopher Read more Letter Canada’s dismantled safeguards threaten salmon By Michael H. H. Price, Adrienne Berchtold Read more Letter Misusing research to trap songbirds in Spain By Juan José Negro, Antoni Margalida, et al. Read more Letter Climate-change extremes threaten Iraq By Bassim Mohammed Hashim, Zaher Mundher Yaseen Read more Reviews Review  |  ARTIFICIAL INTELLIGENCE Transforming mental health research and care through artificial intelligence By Nils Opel, Michael Breakspear Read more Research Research Highlights In Science Journals By Christiana N. Fogg, Jake S. Yeston, et al. Highlights from the Science family of journals Read more Research Highlights In Other Journals By Keith T. Smith, Stella M. Hurtley, et al. Editors’ selections from the current scientific literature Read more Research Article  |  IMMUNOLOGY Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity By Danhui Liu, Chuanli Zhou, et al. Read more Research Article  |  IMMUNOLOGY Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation By Jieru Deng, Yuting Yan, et al. Read more Research Article  |  DEVELOPMENT Subventricular zone radial glial cells maintain inhibitory neuron production in the human brain By Longzhong Jia, Xiaohan Li, et al. Read more Research Article  |  PEROVSKITE EMITTERS A hierarchical shell locks and stabilizes perovskite nanocrystals with near-unity quantum yield By Qingsen Zeng, Yue Zhao, et al. Read more Research Article  |  CARDIOLOGY Deep-learning analysis of 3D microarchitectural remodeling in hypertrophic cardiomyopathy By Eric Q. Wei, Martin Beyer, et al. Read more Research Article  |  ORGANIC CHEMISTRY The photohydrolysis of furans By Nils Frank, Moreshwar B. Chaudhari, et al. Read more Research Article  |  PESTICIDE RISKS Chronic low-dose exposure to chlorpyrifos reduces life span in a wild fish by accelerating aging By Kai Huang, Zihan Zhang, et al. Read more Research Article  |  RADIO ASTRONOMY A sudden change and recovery in the magnetic environment around a repeating fast radio burst By Y. Li, S. B. Zhang, et al. Read more Research Article  |  PALEONTOLOGY Paleogeography modulates marine extinction risk throughout the Phanerozoic By Cooper M. Malanoski, Seth Finnegan, et al. Read more Research Article  |  QUANTUM SIMULATION Characterizing transport in a quantum gas by measuring Drude weights By Philipp Schüttelkopf, Mohammadamin Tajik, et al. Read more Research Article  |  PLATE TECTONICS Low-frequency earthquakes track the motion of a captured slab fragment By David R. Shelly, Amanda M. Thomas, et al. Read more Research Article  |  VERTEBRATE PALEONTOLOGY A diminutive tyrannosaur lived alongside Tyrannosaurus rex By Christopher T. Griffin, Jeb Bugos, et al. Read more Research Article  |  METABOLISM Ablation of Prdm16 and beige fat identity causes vascular remodeling and elevated blood pressure By Mascha Koenen, Tobias Becher, et al. Read more Research Article  |  POLAR SCIENCE Complex mesoscale landscapes beneath Antarctica mapped from space By Helen Ockenden, Robert G. Bingham, et al. Read more Careers Working Life Growing pains By Alanna Lecher Read more FIRST RELEASE Read accepted papers posted online ahead of journal publication View all First Release Sign up for ScienceAdviser Science’s free daily newsletter delivers exclusive reporting and analysis as well as the latest science news, commentary, and research. Sign up to delve deeper into what matters most in Science and science. Sign up Journals Science Science Advances Science Immunology Science Robotics Science Signaling Science Translational Medicine Useful links News Careers Commentary Podcast Webinars Prizes and Awards Help Access & Subscriptions Reprints & Permissions Contact Us Follow us

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