May 2025
Volume 41Issue 5p359-450, e1-e2
Transposable elements (TEs) can "jump" through the genome, much
like monkeys move through a forest. But various host defense mechanisms actively
counteract their transposition. In this issue, Yuka Iwasaki, Keisuke Shoji, Shinichi
Nakagawa, Tomoichiro Miyoshi, and Yukihide Tomari discuss these host defense
mechanisms and explore the dynamic coevolution of TEs and host defenses in animals.
They highlight how these defense mechanisms not only safeguard host genomes but
also drive genetic innovation, constantly reshaping genome architecture and function.
Illustration by Hiroko Uchida....Show more
Transposable elements (TEs) can "jump" through the genome, much
like monkeys move through a forest. But various host defense mechanisms actively
counteract their transposition. In this issue, Yuka Iwasaki, Keisuke Shoji, Shinichi
Nakagawa, Tomoichiro Miyoshi, and Yukihide Tomari discuss these host defense
mechanisms and explore the dynamic coevolution of TEs and host defenses in animals.
They highlight how these defense mechanisms not only safeguard host genomes but
also drive genetic innovation, constantly reshaping genome architecture and function.
Illustration by Hiroko Uchida.