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Current Issue of Nature

Volume 607 Issue 7918, 14 July 2022
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Volume 607 Issue 7918, 14 July 2022

Canine connection

Although the domestic dog can trace its origins to the grey wolf (Canis lupus), exactly when, where and how domestication happened has remained a source of debate. In this week’s issue, Anders Bergström, Pontus Skoglund and their colleagues, take a step towards resolving this question. The researchers analysed the genomes of 72 ancient wolves from across Europe, Siberia and North America, and spanning the past 100,000 years. They found that dogs are most closely related to ancient wolves from eastern Eurasia but that dogs in the Near East and Africa derive up to half their ancestry from a distinct population related to modern southwest Eurasian wolves. Although none of the genomes analysed was a direct match for either dog ancestry, the researchers say that it has narrowed down where next to look for the ancestors of domestic dogs.

Cover image: Mark Carwardine/Nature Picture Library

This Week

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News in Focus

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  • News & Views

    • In regions of the globe at middle and high latitudes, glacial periods have waxed and waned for hundreds of millennia. Glacier-derived sediment in a Peruvian lake suggests that tropical glaciers have moved to a similar beat.

      • Aaron E. Putnam
      News & Views
    • A combination of functional imaging and gene-expression profiling in brain tissue has been used to unravel the properties of 35 subtypes of neuron in mice, revealing a gene-expression axis that governs each subtype’s activity.

      • Hongkui Zeng
      • Saskia E. J. de Vries
      News & Views
    • Lung samples housed in medical archives have yielded three genomes for the influenza A virus that caused the 1918 global pandemic. The sequences reveal mutations that might have triggered the pandemic’s devastating second wave.

      • Martha I. Nelson
      • Elodie Ghedin
      News & Views
    • Self-assembling ‘crystals’ of starfish embryos exhibit a curious behaviour termed odd elasticity, which seemingly violates Newton’s laws of classical mechanics. This discovery poses questions for physicists and biologists alike.

      • Jack Binysh
      • Anton Souslov
      News & Views
    • The discovery that gut viruses can be transmitted from mouse pups to their mothers in saliva during breastfeeding reveals previously unrecognized sites of viral replication and means of viral transmission.

      • Elizabeth A. Kennedy
      • Megan T. Baldridge
      News & Views
  • Reviews

  • Articles

    • Analysis of the pulse profile of a fast radio burst showed sub-second periodicity, providing evidence for a neutron-star origin of the event and favouring emission arising from the magnetosphere.

      • Bridget C. Andersen
      • Kevin Bandura
      • Andrew Zwaniga
    • Individually addressable ‘T centre’ photon-spin qubits are integrated in silicon photonic structures and their spin-dependent telecommunications-band optical transitions characterized, creating opportunities to construct silicon-integrated, telecommunications-band quantum information networks.

      • Daniel B. Higginbottom
      • Alexander T. K. Kurkjian
      • Stephanie Simmons
    • Control loops generically produce braids of eigenfrequencies, and these braids form a non-Abelian group that reflects the non-trivial geometry of the space of degeneracies; these features are demonstrated experimentally using a cavity optomechanical system.

      • Yogesh S. S. Patil
      • Judith Höller
      • Jack G. E. Harris
    • The phase diagram of the unconventional superconductor Sr2RuO4 in both normal and superconducting states is mapped out using high-precision measurements of the elastocaloric effect, showing similarities to other unconventional superconductors as well as unique features.

      • You-Sheng Li
      • Markus Garst
      • Andrew P. Mackenzie
      Article Open Access
    • Experiments show that swimming starfish embryos spontaneously assemble into large chiral crystals that exhibit self-sustained chiral oscillations and unconventional deformation responses characteristic of odd elastic materials.

      • Tzer Han Tan
      • Alexander Mietke
      • Nikta Fakhri
    • Analysis of a continuous and independently dated record of glaciation in the tropical Andes spanning 700,000 years shows that Andean glaciation follows patterns of global ice volume change, with a periodicity of approximately 100,000 years.

      • D. T. Rodbell
      • R. G. Hatfield
      • S. Pierdominici
      Article Open Access
    • Suppression of salicylic acid production in Arabidopsis thaliana at high temperature is caused by decreased recruitment of GUANYLATE BINDING PROTEIN-LIKE 3 defence-associated condensates on promoter sites of master immune regulatory genes.

      • Jong Hum Kim
      • Christian Danve M. Castroverde
      • Sheng Yang He
      Article Open Access
    • Enteric viruses replicate in salivary glands, can be propagated in salivary gland-derived spheroids and cell lines, and are released into saliva, which is a new transmission route having implications for therapeutics, diagnostics and sanitation measures.  

      • S. Ghosh
      • M. Kumar
      • N. Altan-Bonnet
    • A study quantifying the neutralization of severe acute respiratory syndrome coronavirus 2 variants in individuals infected with Omicron/BA.1 shows that vaccinated individuals previously infected with Omicron have enhanced protection against reinfection with current variants, \including Omicron/BA.2, while Omicron/BA.1 infected unvaccinated individuals have limited protection.

      • Khadija Khan
      • Farina Karim
      • Alex Sigal
      Article Open Access
    • Synthetic chimeric orthogonal IL-2 receptors that incorporate the intracellular domain of receptors for other γ-chain cytokines such as IL-9 can reroute orthogonal signalling and alter the phenotype of T cells to improve anti-tumour responses.

      • Anusha Kalbasi
      • Mikko Siurala
      • K. Christopher Garcia
    • The core cell cycle is largely driven by increasing total CDK activity together with minor differences in the substrate specificity of the CDKs initiating DNA replication and mitosis.

      • Souradeep Basu
      • Jessica Greenwood
      • Paul Nurse
      Article Open Access
    • A study demonstrates the rational de novo design of water-soluble assemblies constructed from long 310-helical peptides, and details their characterization by circular dichroism spectroscopy, analytical ultracentrifugation and X-ray crystallography.

      • Prasun Kumar
      • Neil G. Paterson
      • Derek N. Woolfson
    • Cryo-electron microscopy structures of Drosophila Dicer-2–R2D2 complexes with and without small interfering RNA reveal how the RNA is presented to Argonaute in the correct orientation for viral gene silencing.

      • Sonomi Yamaguchi
      • Masahiro Naganuma
      • Osamu Nureki
      Article Open Access
    • Structures of the Dcr-2–Loqs-PD complex while it is processing a double-stranded RNA (dsRNA) substrate elucidate the interactions between Dcr-2 and Loqs-PD, and show that Dcr-2 undergoes substantial conformational changes during a dsRNA-processing cycle.

      • Shichen Su
      • Jia Wang
      • Jinbiao Ma
      Article Open Access
  • Matters Arising

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